Exam 1: The Study of Behavioral Endocrinology
Which statement is not true of hormones?
C
List three advantages and three disadvantages of using nonhuman animals in behavioral endocrinology research.
Advantages may include:
Continuity of behavior from one species to another through evolution
Simplest system with qualities of interest
More economical to develop methods on animals that may be useful for people
Ethical considerations (some manipulations are not permissible in humans)
Function of behavior often becomes clearer when viewed in a comparative manner
Places human system in perspective
Generalizations can be gained from animal models then tested in humans
Disadvantages may include:
Enormous species differences: behaviors may represent adaptations to very specific environments
Behavioral gap between animals and humans is great because of language & cultural evolution; to get the "cleanest" answers about simplest analyses, the less cognition, the better
Ethical considerations
Describe how you might use an optogenetic approach to explore a question of interest in behavioral endocrinology. What are the advantages of using such an approach relative to more classical approaches such as lesions and pharmacology? What are the disadvantages?
Optogenetics is a powerful technique that involves the use of light to control the activity of specific neurons in the brain. In the context of behavioral endocrinology, optogenetics can be used to explore the role of specific hormone-sensitive neurons in regulating behavior. For example, researchers could use optogenetics to selectively activate or inhibit neurons that respond to hormones such as oxytocin or testosterone, and then observe the effects on behavior.
One advantage of using optogenetics in behavioral endocrinology is the ability to precisely target and manipulate specific neural circuits. This allows for a more precise and specific investigation of the role of hormone-sensitive neurons in behavior, compared to more classical approaches such as lesions or pharmacology. Additionally, optogenetics allows for the temporal control of neural activity, meaning that researchers can precisely control when and for how long specific neurons are activated or inhibited, providing a level of control that is not possible with other techniques.
However, there are also some disadvantages to using optogenetics. One potential limitation is the need for specialized equipment and expertise, which can make it more challenging for some researchers to adopt this technique. Additionally, optogenetic manipulations may not fully replicate the natural patterns of neural activity that occur in response to endogenous hormone release, which could limit the generalizability of findings.
In conclusion, optogenetics offers a powerful and precise approach to exploring questions in behavioral endocrinology by allowing for the specific manipulation of hormone-sensitive neurons. While there are some limitations to consider, the advantages of optogenetics in terms of precision and temporal control make it a valuable tool for investigating the neural basis of hormone-behavior interactions.
Which of the following is true regarding the differences between neural and hormonal communication?
Hormones may affect behavior by affecting any of the following, except
Which of the following is the best evidence of hormone-behavior interactions?
One drawback of using electrolytic lesions in studies of hormones and behavior is that these lesions
SEQ CHAPTER \h \r 1Briefly describe Berthold's experiment on roosters. What was the main finding?
List two differences and one similarity between the endocrine and nervous systems.
List six common techniques used in the study of behavioral endocrinology.
What does an fMRI measure and how has it advanced the field of behavioral neuroendocrinology?
The primary difference between hormones and neurotransmitters is that
Which of the following terms does not refer to a genetically manipulated animal used in behavioral endocrinology research?
In lesion studies or studies of animals with specific genes deleted, behavioral tests study the effects of the missing brain region or the missing gene, respectively. Discuss how these conceptual shortcomings can be overcome in evaluating the results of studies using these types of procedures.
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