Exam 20: Immunity to Tumors

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For each description in questions , choose the tumor antigen or gene (A-J) that is the best match. -A patient presenting with jaundice and a recent 11-kg (20 lb) weight loss who has a history of hepatitis B infection will most likely have elevated levels of this glycoprotein

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A

Matching For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs. -Cancer testis antigens

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For each description in questions , choose the tumor antigen or gene (A-J) that is the best match. -A mucin that is often elevated in ovarian carcinoma

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C

For each of the descriptions in questions , select the tumor immunotherapy strategy (A-J) that is best match. -Therapy that targets an antigen that is not essential to the malignant phenotype of the tumor; antigen-loss variants can emerge during therapy

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For each of the descriptions in questions , select the tumor immunotherapy strategy (A-J) that is best match. -Component of adoptive cellular immunotherapy used with IL-2 and/or chemotherapeutic drugs

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Matching For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs. -Carcinoembryonic antigen (CEA)

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Matching For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs. -Prostate-specific antigen

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Matching For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs. -E6 antigen

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A 17-year-old girl from southern China has had a sore throat and fever for 1 week. On physical examination, generalized lymphadenopathy is noted. A rapid strep test for streptococcal infection is negative and a CBC shows 20% atypical lymphocytes. A Monospot test for the presence of heterophile antibodies is positive. This illness is associated with eventual development of which of the following malignancies?

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For each description in questions , choose the tumor antigen or gene (A-J) that is the best match. -Differentiation antigen for B cells

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For each of the descriptions in questions , select the tumor immunotherapy strategy (A-J) that is best match. -Tumor cells transfected with the gene encoding this protein have been used as a vaccine that promotes dendritic cell presentation of tumor antigens

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For each description in questions , choose the tumor antigen or gene (A-J) that is the best match. -Mutations in both allelic copies of this gene are required for malignant transformation

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Matching For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs. -Ras

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For each description in questions , choose the tumor antigen or gene (A-J) that is the best match. -A protein that is expressed only in immunologically privileged tissue

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