Question 1

What event takes place during interphase?

Accepted Answer

A)  Centromeres divide. 
B)  Metabolic processes, such as DNA replication, are carried out by the cell. 
C)  Spindle fibers start forming. 
D)  Centrioles begin to appear. 
A)  Centromeres divide. 
B)  Metabolic processes, such as DNA replication, are carried out by the cell. 
C)  Spindle fibers start forming. 
D)  Centrioles begin to appear. B

Question 2

In which of the following cell types do G1 and G2 not take place?

Accepted Answer

A)  Early embryonic cells 
B)  Budding yeast cells 
C)  Typical proliferating human cells 
D)  Skin fibroblasts 
A)  Early embryonic cells 
B)  Budding yeast cells 
C)  Typical proliferating human cells 
D)  Skin fibroblasts A

Question 3

Identify the four different molecular mechanisms by which the activity of cyclin-dependent kinases is regulated after they are synthesized.

Accepted Answer

(1) Association of a Cdk with its partner cyclin; (2) phosphorylation of an activating threonine; (3) phosphorylation and dephosphorylation of inhibiting tyrosine and threonine residues; and (4) binding of Cdk inhibitors.

Question 4

In yeast, START triggers the progression from G1 to S. Which of the following are involved in regulating START?

Accepted Answer

A)  Nutrients 
B)  Mating factors 
C)  Cell size 
D)  All of the above 
A)  Nutrients 
B)  Mating factors 
C)  Cell size 
D)  All of the above

Question 5

Why is Rb, a product of the retinoblastoma gene, now termed a member of a family of proteins designated tumor suppressor genes?

Accepted Answer

Normally, Rb exists in an underphosphory

Question 6

Two sea urchin proteins were named cyclin A and B because, during the embryonic cell cycle, they were periodically

Accepted Answer

A)  activated and inactivated by phosphorylation and dephosphorylation. 
B)  synthesized and degraded. 
C)  bound and released by another protein. 
D)  ubiquitylated and nonubiquitylated. 
A)  activated and inactivated by phosphorylation and dephosphorylation. 
B)  synthesized and degraded. 
C)  bound and released by another protein. 
D)  ubiquitylated and nonubiquitylated.

Question 7

The progression from metaphase to anaphase results from

Accepted Answer

A)  phosphorylation mediated by Polo-like kinase. 
B)  ubiquitin-mediated proteolysis of key regulatory proteins. 
C)  phosphorylation mediated by Cdk2. 
D)  activation by Wee1. 
A)  phosphorylation mediated by Polo-like kinase. 
B)  ubiquitin-mediated proteolysis of key regulatory proteins. 
C)  phosphorylation mediated by Cdk2. 
D)  activation by Wee1.

Question 8

Which of the following is not one of the phases of mitosis?

Accepted Answer

A)  Prophase 
B)  S phase 
C)  Metaphase 
D)  Anaphase 
A)  Prophase 
B)  S phase 
C)  Metaphase 
D)  Anaphase

Question 9

Transcription ceases as chromosome condensation occurs.

Accepted Answer

A) True 
 B)False

Question 10

Rb is a tumor suppressor protein that acts by inhibiting phosphorylation of Cdk.

Accepted Answer

A) True 
 B)False

Question 11

The spindle assembly checkpoint monitors the alignment of chromosomes on the _______.

Accepted Answer

The answer of The spindle assembly checkpoint monitors the alignment...

Question 12

The eukaryotic cell cycle is composed of four phases in the following order:

Accepted Answer

A)  G1; S; G2; M. 
B)  G1; G2; S; M. 
C)  G1; M; G2; S. 
D)  S; G1; G2; M. 
A)  G1; S; G2; M. 
B)  G1; G2; S; M. 
C)  G1; M; G2; S. 
D)  S; G1; G2; M.

Question 13

Injection of MPF into frog oocytes induces them to enter _______.

Accepted Answer

The answer of Injection of MPF into frog oocytes induces...

Question 14

Chromosomes are attached to spindle microtubules by

Accepted Answer

A)  centromeres. 
B)  kinetochores. 
C)  centrioles. 
D)  centrosomes. 
A)  centromeres. 
B)  kinetochores. 
C)  centrioles. 
D)  centrosomes.

Question 15

Briefly describe how Hunt and colleagues identified cyclins and why they named them "cyclins"?

Accepted Answer

Hunt et al. knew that upon fertilization

Question 16

The DNA region to which proteins bind to form the kinetochore and spindle fibers attach for segregation of the chromosomes is called the

Accepted Answer

A)  chiasma. 
B)  centromere. 
C)  synaptonemal complex. 
D)  origin. 
A)  chiasma. 
B)  centromere. 
C)  synaptonemal complex. 
D)  origin.

Question 17

Entry into mitosis occurs because

Accepted Answer

A)  cyclin is destroyed at the beginning of mitosis. 
B)  cyclin is phosphorylated at the beginning of mitosis. 
C)  sufficient cyclin-dependent kinase is synthesized to trigger mitosis. 
D)  Cdk1/Cyclin B (MPF) get activated. 
A)  cyclin is destroyed at the beginning of mitosis. 
B)  cyclin is phosphorylated at the beginning of mitosis. 
C)  sufficient cyclin-dependent kinase is synthesized to trigger mitosis. 
D)  Cdk1/Cyclin B (MPF) get activated.

Question 18

In animal cells, Cdk2/cyclin A act to drive cells through the restriction point in G1.

Accepted Answer

A) True 
 B)False

Question 19

The G1 checkpoint in budding yeast cells is called

Accepted Answer

A)  START. 
B)  the restriction point. 
C)  the decision point. 
D)  the G1/S boundary. 
A)  START. 
B)  the restriction point. 
C)  the decision point. 
D)  the G1/S boundary.

Question 20

The degradation of cyclin B during _______ occurs after it becomes modified by the addition of ubiquitin.

Accepted Answer

The answer of The degradation of cyclin B during _______...

What event takes place during interphase?

In which of the following cell types do G₁ and G₂ not take place?

Identify the four different molecular mechanisms by which the activity of cyclin-dependent kinases is regulated after they are synthesized.

In yeast, START triggers the progression from G₁ to S. Which of the following are involved in regulating START?

Why is Rb, a product of the retinoblastoma gene, now termed a member of a family of proteins designated tumor suppressor genes?

Two sea urchin proteins were named cyclin A and B because, during the embryonic cell cycle, they were periodically

The progression from metaphase to anaphase results from

Which of the following is not one of the phases of mitosis?

Transcription ceases as chromosome condensation occurs.

Rb is a tumor suppressor protein that acts by inhibiting phosphorylation of Cdk.

The spindle assembly checkpoint monitors the alignment of chromosomes on the _______.

The eukaryotic cell cycle is composed of four phases in the following order:

Injection of MPF into frog oocytes induces them to enter _______.

Chromosomes are attached to spindle microtubules by

Briefly describe how Hunt and colleagues identified cyclins and why they named them "cyclins"?

The DNA region to which proteins bind to form the kinetochore and spindle fibers attach for segregation of the chromosomes is called the

Entry into mitosis occurs because

In animal cells, Cdk2/cyclin A act to drive cells through the restriction point in G₁.

The G₁ checkpoint in budding yeast cells is called

The degradation of cyclin B during _______ occurs after it becomes modified by the addition of ubiquitin.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

Cell Death and Cell Renewal

Cancer

Filters

Exam 18: The Cell Cycle

What event takes place during interphase?

In which of the following cell types do G1 and G2 not take place?

Identify the four different molecular mechanisms by which the activity of cyclin-dependent kinases is regulated after they are synthesized.

In yeast, START triggers the progression from G1 to S. Which of the following are involved in regulating START?

Why is Rb, a product of the retinoblastoma gene, now termed a member of a family of proteins designated tumor suppressor genes?

Two sea urchin proteins were named cyclin A and B because, during the embryonic cell cycle, they were periodically

The progression from metaphase to anaphase results from

Which of the following is not one of the phases of mitosis?

Transcription ceases as chromosome condensation occurs.

Rb is a tumor suppressor protein that acts by inhibiting phosphorylation of Cdk.

The spindle assembly checkpoint monitors the alignment of chromosomes on the _______.

The eukaryotic cell cycle is composed of four phases in the following order:

Injection of MPF into frog oocytes induces them to enter _______.

Chromosomes are attached to spindle microtubules by

Briefly describe how Hunt and colleagues identified cyclins and why they named them "cyclins"?

The DNA region to which proteins bind to form the kinetochore and spindle fibers attach for segregation of the chromosomes is called the

Entry into mitosis occurs because

In animal cells, Cdk2/cyclin A act to drive cells through the restriction point in G1.

The G1 checkpoint in budding yeast cells is called

The degradation of cyclin B during _______ occurs after it becomes modified by the addition of ubiquitin.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

Cell Death and Cell Renewal

Cancer

Filters

In which of the following cell types do G₁ and G₂ not take place?

In yeast, START triggers the progression from G₁ to S. Which of the following are involved in regulating START?

In animal cells, Cdk2/cyclin A act to drive cells through the restriction point in G₁.

The G₁ checkpoint in budding yeast cells is called