Question 1

The TATA box is similar to the _______ in E. coli.

Accepted Answer

A)  -35 promoter sequence 
B)  -10 promoter sequence 
C)  +1 transcription start site 
D)  None of the above 
A)  -35 promoter sequence 
B)  -10 promoter sequence 
C)  +1 transcription start site 
D)  None of the above B

Question 2

What role do the modified bases in the tRNA molecule play?

Accepted Answer

It is believed that some of these modified bases play a role in protein synthesis by altering the base-pairing properties of the tRNA molecule.

Question 3

RNA polymerase differs from DNA polymerase in that it

Accepted Answer

A)  synthesizes new strands of RNA in a 3ʹ to 5ʹ direction. 
B)  is a monomeric protein. 
C)  can synthesize a complementary strand without the two strands of DNA being separated. 
D)  does not require a primer to initiate synthesis of RNA. 
A)  synthesizes new strands of RNA in a 3ʹ to 5ʹ direction. 
B)  is a monomeric protein. 
C)  can synthesize a complementary strand without the two strands of DNA being separated. 
D)  does not require a primer to initiate synthesis of RNA. D

Question 4

A yeast mutant shows decreased expression of the 5.8S rRNA, the 5S rRNA, and protein-encoding mRNAs. If only one gene is mutated, which of the following genes is most likely affected?

Accepted Answer

A)  TATA-binding protein (TBP) 
B)  Upstream binding factor (UBF) 
C)  RNA polymerase III 
D)  TFIIB 
A)  TATA-binding protein (TBP) 
B)  Upstream binding factor (UBF) 
C)  RNA polymerase III 
D)  TFIIB

Question 5

The RNA components of the spliceosome are five different

Accepted Answer

A)  small cytoplasmic RNAs. 
B)  small nuclear RNAs. 
C)  microRNAs. 
D)  siRNAs. 
A)  small cytoplasmic RNAs. 
B)  small nuclear RNAs. 
C)  microRNAs. 
D)  siRNAs.

Question 6

According to the central dogma of molecular biology, transcription of genetic information occurs via

Accepted Answer

A)  DNA-dependent DNA synthesis. 
B)  DNA-dependent RNA synthesis. 
C)  RNA-dependent DNA synthesis. 
D)  RNA-dependent protein synthesis. 
A)  DNA-dependent DNA synthesis. 
B)  DNA-dependent RNA synthesis. 
C)  RNA-dependent DNA synthesis. 
D)  RNA-dependent protein synthesis.

Question 7

Why is dystrophin absent in Duchenne muscular dystrophy?

Accepted Answer

This is due to mutations in th

Question 8

Which is not part of the spliceosome?

Accepted Answer

A)  U1 
B)  U2 
C)  U3 
D)  U5 
A)  U1 
B)  U2 
C)  U3 
D)  U5

Question 9

When Tetrahymena 28S rRNA is incubated in the absence of proteins, it undergoes _______.

Accepted Answer

The answer of When Tetrahymena 28S rRNA is incubated in...

Question 10

Fertilization stimulates

Accepted Answer

A)  addition of 7-methylguanosine caps to pre-mRNAs. 
B)  the lengthening of poly-A sequences to stored mRNAs in eggs. 
C)  removal of introns from pre-mRNAs. 
D)  the degradation of early developmental mRNAs. 
A)  addition of 7-methylguanosine caps to pre-mRNAs. 
B)  the lengthening of poly-A sequences to stored mRNAs in eggs. 
C)  removal of introns from pre-mRNAs. 
D)  the degradation of early developmental mRNAs.

Question 11

Cytoplasmic degradation of most eukaryotic mRNA is initiated by shortening of their _______.

Accepted Answer

The answer of Cytoplasmic degradation of most eukaryotic mRNA is...

Question 12

The form of apolipoprotein B (Apo-B) produced by the intestine is shorter than the Apo-B produced by the liver. The intestine produces a smaller protein by

Accepted Answer

A)  proteolytic cleavage of the forming polypeptide chain. 
B)  a base alteration that changes a codon for glutamine to a termination codon. 
C)  shortening the mRNA from the 3' end after translation. 
D)  including fewer exons in the mRNA by alternative splicing. 
A)  proteolytic cleavage of the forming polypeptide chain. 
B)  a base alteration that changes a codon for glutamine to a termination codon. 
C)  shortening the mRNA from the 3' end after translation. 
D)  including fewer exons in the mRNA by alternative splicing.

Question 13

Messenger RNAs have varying half-lives in the cytoplasm, and those differences are usually due to differences in the sequences near the 3ʹ end of the mRNA.

Accepted Answer

A) True 
 B)False

Question 14

Unstable mRNAs with very short half-lives are frequently _______ proteins.

Accepted Answer

The answer of Unstable mRNAs with very short half-lives are...

Question 15

Approximately what percentage of the bases in tRNAs are altered to produce a variety of modified nucleotides within the tRNA molecule?

Accepted Answer

A)  2% 
B)  10% 
C)  50% 
D)  90% 
A)  2% 
B)  10% 
C)  50% 
D)  90%

Question 16

tRNA genes are transcribed by RNA polymerase III.

Accepted Answer

A) True 
 B)False

Question 17

What two types of molecules make up snoRNPs?

Accepted Answer

RNA (snoRN

Question 18

Tissue-specific RNA editing can occur.

Accepted Answer

A) True 
 B)False

Question 19

The sigma ($\sigma$) subunit of bacterial RNA polymerase remains associated for the addition of _______ during transcription.

Accepted Answer

A)  the first ten nucleotides 
B)  the first half of the nucleotides 
C)  all of the nucleotides 
D)  the last ten nucleotides 
A)  the first ten nucleotides 
B)  the first half of the nucleotides 
C)  all of the nucleotides 
D)  the last ten nucleotides

Question 20

Explain both the closed- and open-promoter complex that is formed during the initiation of transcription in E. coli.

Accepted Answer

RNA polymerase initially binds nonspecif

The TATA box is similar to the _______ in E. coli.

What role do the modified bases in the tRNA molecule play?

RNA polymerase differs from DNA polymerase in that it

A yeast mutant shows decreased expression of the 5.8S rRNA, the 5S rRNA, and protein-encoding mRNAs. If only one gene is mutated, which of the following genes is most likely affected?

The RNA components of the spliceosome are five different

According to the central dogma of molecular biology, transcription of genetic information occurs via

Why is dystrophin absent in Duchenne muscular dystrophy?

Which is not part of the spliceosome?

When Tetrahymena 28S rRNA is incubated in the absence of proteins, it undergoes _______.

Fertilization stimulates

Cytoplasmic degradation of most eukaryotic mRNA is initiated by shortening of their _______.

The form of apolipoprotein B (Apo-B) produced by the intestine is shorter than the Apo-B produced by the liver. The intestine produces a smaller protein by

Messenger RNAs have varying half-lives in the cytoplasm, and those differences are usually due to differences in the sequences near the 3ʹ end of the mRNA.

Unstable mRNAs with very short half-lives are frequently _______ proteins.

Approximately what percentage of the bases in tRNAs are altered to produce a variety of modified nucleotides within the tRNA molecule?

tRNA genes are transcribed by RNA polymerase III.

What two types of molecules make up snoRNPs?

Tissue-specific RNA editing can occur.

The sigma ( $\sigma$ ) subunit of bacterial RNA polymerase remains associated for the addition of _______ during transcription.

Explain both the closed- and open-promoter complex that is formed during the initiation of transcription in E. coli.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 8: RNA Synthesis and Processing

The TATA box is similar to the _______ in E. coli.

What role do the modified bases in the tRNA molecule play?

RNA polymerase differs from DNA polymerase in that it

A yeast mutant shows decreased expression of the 5.8S rRNA, the 5S rRNA, and protein-encoding mRNAs. If only one gene is mutated, which of the following genes is most likely affected?

The RNA components of the spliceosome are five different

According to the central dogma of molecular biology, transcription of genetic information occurs via

Why is dystrophin absent in Duchenne muscular dystrophy?

Which is not part of the spliceosome?

When Tetrahymena 28S rRNA is incubated in the absence of proteins, it undergoes _______.

Fertilization stimulates

Cytoplasmic degradation of most eukaryotic mRNA is initiated by shortening of their _______.

The form of apolipoprotein B (Apo-B) produced by the intestine is shorter than the Apo-B produced by the liver. The intestine produces a smaller protein by

Messenger RNAs have varying half-lives in the cytoplasm, and those differences are usually due to differences in the sequences near the 3ʹ end of the mRNA.

Unstable mRNAs with very short half-lives are frequently _______ proteins.

Approximately what percentage of the bases in tRNAs are altered to produce a variety of modified nucleotides within the tRNA molecule?

tRNA genes are transcribed by RNA polymerase III.

What two types of molecules make up snoRNPs?

Tissue-specific RNA editing can occur.

The sigma ( σ\sigmaσ ) subunit of bacterial RNA polymerase remains associated for the addition of _______ during transcription.

Explain both the closed- and open-promoter complex that is formed during the initiation of transcription in E. coli.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

The sigma ( $\sigma$ ) subunit of bacterial RNA polymerase remains associated for the addition of _______ during transcription.