Exam 8: Activity-Guided Neural Development

In visual system development, axons travel from the retina to their approximate correct position in the lateral geniculate nucleus by

Long-term potentiation in the hippocampus is mediated by

What evidence suggests that changes in muscles are responsible for the extent of apoptosis in motor neurons? How may neurotrophic factors mediate this process?

In addition to existing synapses simply getting stronger or weaker, what else drives Hebbian synaptic plasticity? Why must Hebbian competition require communication between inputs to a given neuron?

Subjecting neurons in the perforant pathway to tetanus stimulation strengthens activity in the dentate gyrus, indicating that

The net loss of cortical synapses during childhood is

Unlike in adult rats, muscle fibers in newborn rats

Sympathetic and parasympathetic neurons typically have _______ effects on their target organ.

In vertebrates, the right visual cortex receives information from the

The segregation of input from the two eyes in the developing lateral geniculate nucleus is driven by

AMPA receptors produce stable excitatory responses at _______ rates of stimulation, and NMDA receptors produce increased synaptic responses at _______ rates of stimulation.

A Hebbian synapse becomes _______ when it causes the _______ neuron to fire.

Which neurotransmitter does the hippocampus primarily use?

Describe the mechanism by which magnesium interacts with NMDA receptors when hippocampal afferents are stimulated at slow versus fast rates. What three changes occur after fast rate stimulation that contribute to long-term potentiation in the hippocampus?