Chat with AIExam 5: Development of the Brain
The particular fate of an undifferentiated cell depends partially upon which factor?
(39) 
VerifiedB
In neurogenesis, cells that give rise to neurons divide in via mitosis, which takes place within the _______ zone inside the neural tube.
(43) VerifiedD
Citing experimental evidence, describe how the synaptic targets of developing neurons regulate cell death.
(33) 
Answered by Examlex AI CopilotDuring development, neurons form connections with specific target cells through synapses. Experimental evidence has shown that the synaptic targets of developing neurons play a crucial role in regulating cell death. One study conducted by Lu and colleagues (2009) demonstrated that the presence of appropriate synaptic targets can promote the survival of developing neurons, while the absence of such targets can lead to increased cell death.
Furthermore, research by Park and Poo (2013) revealed that the activity of synaptic targets, such as the release of neurotrophic factors, can directly influence the survival and death of developing neurons. Specifically, the activation of neurotrophic factor receptors on developing neurons by synaptic targets has been shown to promote cell survival by inhibiting apoptotic pathways.
Overall, experimental evidence suggests that the synaptic targets of developing neurons play a critical role in regulating cell death through the promotion of cell survival signals and the inhibition of apoptotic pathways. This highlights the importance of proper synaptic connectivity in the development and maintenance of neuronal populations.
What are the structural changes seen in the brain of a patient with Alzheimer's disease?
(32) In the human cerebral cortex, the pruning of dendrites and axon terminals occurs last in _______ cortex.
(29) Which brain areas are affected by light deprivation of one eye during the critical period? What is the effect on cortical neurons?
(32) Which of the following can postpone the appearance of Alzheimer's disease?
(38) Explain how methylation of genes in the brains of rodents can be affected by experience.
(37) The importance of loss of synapses during development is demonstrated in people with _______, a condition in which the normal elimination of synapses after birth does not occur, leading to intellectual disability.
(34) In human embryonic development, the crests of the neural groove come together to form the
(43) At the cellular level, certain regions of the brains of individuals with Alzheimer's show strange patches termed _______ plaques.
(29) People affected by Fragile X syndrome have a chromosome that is prone to breaking because the DNA at one site is
(41) The mitotic division of nonneural cells to produce neurons is called
(37) What are neurotrophic factors? Describe the role they play in neural connections to target structures.
(39) In human embryonic development, the beginning of the brain is evident in the anterior portion of the neural tube by day
(44) The physical characteristics that make up an individual and constantly change throughout out life are called the individual's
(40) Describe the process of synaptic rearrangement in the developing brain.
(40) In people with Alzheimer's disease, amyloid plaques are found in the _______, cortex, and associated limbic system sites.
(28) Adult neurogenesis especially affects a region of a brain that would help a person
(30) The use of _______, which has an affinity for beta-amyloid, means a formal diagnosis of Alzheimer's can now occur prior to death.
(26) 
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