Exam 13: The Citric Acid Cycle

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What are the fewest number of turns of the citric acid cycle needed before carbon radioactive in both carbons of the acetyl group in acetyl Co A are incorporated into all 4 carbons in every molecule of oxaloacetate produced?

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C

Which of the following is not a fate of a citric acid cycle intermediate?

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D

Pyruvate translocase is specific for transporting pyruvate across the inner mitochondrial membrane.

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True

Each of the following catalyzed reactions of the citric acid cycle appears to be regulated except

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Which cofactor is not used by the pyruvate dehydrogenase complex?

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The carbon atoms that enter the citric acid cycle via acetyl CoA are the same ones released as carbon dioxide during one round of the citric acid cycle.

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Why were muscle cells and extracts the best choice for Krebs,Johnson and Szent-Györgyi to elucidate the cyclic nature of the citric acid cycle?

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Which carbon atom(s)of pyruvate is(are)first converted to carbon dioxide by pyruvate dehydrogenase complex?

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The citric acid cycle oxidizes pyruvate,and some of the pathway intermediates are starting materials for many biosynthetic pathways.This means that the citric acid cycle is ________.

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Aqueous channels in cell membranes that small molecules such as pyruvate can pass through are formed by transmembrane proteins called

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Which of the following allosterically activates mammalian isocitrate dehydrogenase?

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A metabolic pathway that is both catabolic and anabolic is ________.An example of such a pathway is ________.

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Most bacteria do not have a complete citric acid cycle.

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What is the role of mitochondrial PEPCK?

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The pyruvate dehydrogenase complex is larger than a ribosome.In bacteria these complexes are located in the cytosol while they are found in ________ of eukaryotes

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The net effect of the eight steps of the citric acid cycle is to

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Please match the following reactions to their respective energy yielding products. Please note that a product may be used once,more than once,or not at all as an answer. -Succinate dehydrogenase complex

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Which of the following inhibit(s)pyruvate dehydrogenase kinase?

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NAD-dependent malate dehydrogenase

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In aerobic prokaryotes,the succinate dehydrogenase complex is embedded in the inner mitochondrial membrane.

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