Question 1

In the glycerol phosphate shuttle,reducing equivalents from NADH enter the electron transport system by reactions carrying electrons to ________.

Accepted Answer

A) complex III 
B) complex IV 
C) malate 
D) complex I 
A) complex III 
B) complex IV 
C) malate 
D) complex I A

Question 2

Electron flow to oxidize electron carriers does not occur in anaerobic organisms.

Accepted Answer

A) True 
 B)False  False

Question 3

The formation of ATP from ADP and Pi in the mitochondrial matrix requires both symport and antiport transporters.

Accepted Answer

A) True 
 B)False  True

Question 4

At one time the uncoupler 2,4-dinitrophenol was used as a weight reducing drug.Its side-effects,including death,resulted in its discontinued use.How could this drug cause weight loss?

Accepted Answer

A) The uncoupler allows the oxidation of fats from adipose tissue without the production of ATP.This allows the oxidation to proceed continuously and use up the fats. 
B) The uncoupler causes ATP to be produced at a much higher rate than normal and this causes weight loss. 
C) The uncoupler inhibits the transport of pyruvate into the matrix of the mitochondria.Fats are then degraded to glycerol and subsequently to pyruvate to provide the necessary energy,thereby depleting fat stores. 
D) The uncoupler is an allosteric activator of ATP synthase.This increases the rate of translocation of H+ and the oxidation of fuels,including fats. 
A) The uncoupler allows the oxidation of fats from adipose tissue without the production of ATP.This allows the oxidation to proceed continuously and use up the fats. 
B) The uncoupler causes ATP to be produced at a much higher rate than normal and this causes weight loss. 
C) The uncoupler inhibits the transport of pyruvate into the matrix of the mitochondria.Fats are then degraded to glycerol and subsequently to pyruvate to provide the necessary energy,thereby depleting fat stores. 
D) The uncoupler is an allosteric activator of ATP synthase.This increases the rate of translocation of H+ and the oxidation of fuels,including fats.

Question 5

Which complex in the electron transport chain carries electrons from cytochrome c to molecular oxygen,reducing it to water?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 6

Oxidative phosphorylation requires all of the items listed below except

Accepted Answer

A) ATP synthase in the correct position in the membrane. 
B) enzyme complexes embedded in a membrane. 
C) the flow of electrons from NADH and QH2 in the membrane. 
D) a matrix more positively charged than the intermembrane space. 
E) a terminal electron acceptor which is O2 in mitochondria. 
A) ATP synthase in the correct position in the membrane. 
B) enzyme complexes embedded in a membrane. 
C) the flow of electrons from NADH and QH2 in the membrane. 
D) a matrix more positively charged than the intermembrane space. 
E) a terminal electron acceptor which is O2 in mitochondria.

Question 7

During the Q-cycle ________ molecule(s)of QH² is(are)oxidized and ________ molecule(s)of Q is(are)produced.

Accepted Answer

A) 1;1 
B) 1;2 
C) 2;1 
D) 2;2 
A) 1;1 
B) 1;2 
C) 2;1 
D) 2;2

Question 8

Rotation of the ________ subunit of ATP synthase causes conformational changes in the catalytic sites that produce ATP.

Accepted Answer

A) alpha 
B) beta 
C) gamma 
D) F0 
A) alpha 
B) beta 
C) gamma 
D) F0

Question 9

Complex II in the electron transport chain supplies electrons as ________ to the rest of the chain (complexes III and IV).

Accepted Answer

A)  FADH₂ 
B) Fe-S 
C) succinate 
D) QH2 
A)  FADH₂ 
B) Fe-S 
C) succinate 
D) QH2

Question 10

Which is not a component of complex II?

Accepted Answer

A) Fe-S clusters. 
B) FAD. 
C) Heme. 
D) Cytochrome b. 
E) All of the above are components of complex II. 
A) Fe-S clusters. 
B) FAD. 
C) Heme. 
D) Cytochrome b. 
E) All of the above are components of complex II.

Question 11

E.coli can use electron carriers to grow aerobically or anaerobically.

Accepted Answer

A) True 
 B)False

Question 12

The ________ is between the inner and outer membranes of the mitochondria.

Accepted Answer

A) matrix 
B) intermembrane space 
C) intracellular fluid 
D) ATP synthase complex 
A) matrix 
B) intermembrane space 
C) intracellular fluid 
D) ATP synthase complex

Question 13

How many protons are translocated across the inner mitochondrial membrane by complex IV for every pair of electrons passing through the electron transport chain?

Accepted Answer

A) 0 
B) 1 
C) 2 
D) 3 
E) 4 
A) 0 
B) 1 
C) 2 
D) 3 
E) 4

Question 14

What is the pH difference (△pH)across a membrane at 310 K if the membrane potential is -0.15 V and the overall Gibb's free energy change across the membrane is -19 .0 kJ mol-1? (R = 8.315 J K-1 mol-1;F = 96,485 J V-1 mol-1)

Accepted Answer

A) 5.44 
B) 2.3 
C) 0.74 
D) 1.4 
A) 5.44 
B) 2.3 
C) 0.74 
D) 1.4

Question 15

What is the potential across a membrane if the overall Gibb's free energy change across the membrane is -19.3 kJ mol-1 and the pH difference across the membrane is 0.70 at 310K? (R = 8.315 J K-1 mol-1;F = 96,485 J V-1 mol-1)

Accepted Answer

A) -0.16 V 
B) +.16 V 
C) -0.24 V 
D) +0.24 V 
A) -0.16 V 
B) +.16 V 
C) -0.24 V 
D) +0.24 V

Question 16

Which component of ATP synthase is the site of the proton channel?

Accepted Answer

A) F0. 
B) F1. 
C) F2. 
D) B subunit. 
E) G subunit. 
A) F0. 
B) F1. 
C) F2. 
D) B subunit. 
E) G subunit.

Question 17

The source of energy to produce ATP in mitochondria is a proton gradient formed across the outer mitochondrial membrane.

Accepted Answer

A) True 
 B)False

Question 18

If an inhibitor disrupts the flow of protons from the matrix into the intermembrane space of mitochondria,no ATP will be formed.

Accepted Answer

A) True 
 B)False

Question 19

Which has the highest reduction potential?

Accepted Answer

A) NADH. 
B) Complex I. 
C) Complex II. 
D) O². 
A) NADH. 
B) Complex I. 
C) Complex II. 
D) O².

Question 20

In the respiratory electron transport chain electrons are passed from ________.

Accepted Answer

A) NADH and QH2 to O2 
B) O2 to NAD+ and Q 
C) O2 to NADH 
D) ATP to O2 
A) NADH and QH2 to O2 
B) O2 to NAD+ and Q 
C) O2 to NADH 
D) ATP to O2

Exam 14: Electron Transport and Atp Synthesis

In the glycerol phosphate shuttle,reducing equivalents from NADH enter the electron transport system by reactions carrying electrons to ________.

Electron flow to oxidize electron carriers does not occur in anaerobic organisms.

The formation of ATP from ADP and Pi in the mitochondrial matrix requires both symport and antiport transporters.

At one time the uncoupler 2,4-dinitrophenol was used as a weight reducing drug.Its side-effects,including death,resulted in its discontinued use.How could this drug cause weight loss?

Which complex in the electron transport chain carries electrons from cytochrome c to molecular oxygen,reducing it to water?

Oxidative phosphorylation requires all of the items listed below except

During the Q-cycle ________ molecule(s)of QH² is(are)oxidized and ________ molecule(s)of Q is(are)produced.

Rotation of the ________ subunit of ATP synthase causes conformational changes in the catalytic sites that produce ATP.

Complex II in the electron transport chain supplies electrons as ________ to the rest of the chain (complexes III and IV).

Which is not a component of complex II?

E.coli can use electron carriers to grow aerobically or anaerobically.

The ________ is between the inner and outer membranes of the mitochondria.

How many protons are translocated across the inner mitochondrial membrane by complex IV for every pair of electrons passing through the electron transport chain?

What is the pH difference (△pH)across a membrane at 310 K if the membrane potential is -0.15 V and the overall Gibb's free energy change across the membrane is -19 .0 kJ mol-1? (R = 8.315 J K-1 mol-1;F = 96,485 J V-1 mol-1)

What is the potential across a membrane if the overall Gibb's free energy change across the membrane is -19.3 kJ mol-1 and the pH difference across the membrane is 0.70 at 310K? (R = 8.315 J K-1 mol-1;F = 96,485 J V-1 mol-1)

Which component of ATP synthase is the site of the proton channel?

The source of energy to produce ATP in mitochondria is a proton gradient formed across the outer mitochondrial membrane.

If an inhibitor disrupts the flow of protons from the matrix into the intermembrane space of mitochondria,no ATP will be formed.

Which has the highest reduction potential?

In the respiratory electron transport chain electrons are passed from ________.

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

DNA Replication, repair, and Recombination

Transcription and RNA Processing

Protein Synthesis

Filters

During the Q-cycle molecule(s)of QH² is(are)oxidized and molecule(s)of Q is(are)produced.