Exam 21: Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

What disease state correlates highly with the presence of cytoplasmic vacuoles in freshly drawn blood?

A disorder characterized by a defect in glucocerebrosidase that results in a macrophage with cytoplasm appearing wrinkled or striated is:

Name a type of condition that might cause the following alterations in morphology. a.Toxic granulation b.Vacuolization c.Morulae d.Eosinophilia

A patient has an elevated WBC count with many circulating leukocyte precursors and a normal RBC count.Which of the following assays provides information that can best be used to diagnose this patient?

A neutrophilia that results from a redistribution of neutrophils from the marginating pool into the circulating pool is called:

A 45-year-old female who returned from a trip abroad had nausea and diarrhea,and then later,muscle aches,fever,and chills.She was admitted to a local hospital and was diagnosed with the parasitic disease,trichinosis.Which of the following is most consistent with this disease?

Which of the following characteristics is associated with the neutrophilia that accompanies bacterial infection?

A patient presents with splenomegaly and bone pain.Laboratory findings reveal large macrophages with small eccentric nuclei and cytoplasm with a wrinkled appearance.Further testing shows leukopenia,thrombocytopenia,and anemia.What is the probable cause?

A 78-year-old female receiving chemotherapy for breast cancer had a CBC performed after her last treatment.Her absolute neutrophil count was 1.0 × 10⁹/L.What information can be concluded from this?

An adult patient's blood sample was collected in an EDTA blood collection tube for a CBC.The automated WBC count was 2.1 × 10⁹/L.Upon microscopic examination of the cells,the laboratory professional noted that the neutrophils adhered to the erythrocytes.What corrective action should be taken in this situation?

A patient presents with a leukocyte count of 120 × 10⁹/L and splenomegaly.The blood smear reveals a shift to the left with promyelocytes and blasts.The platelets are increased,and the LAP is decreased.Which condition is associated with these results?

List three laboratory results that can distinguish a leukemoid reaction from CML.

A neutrophil contains many giant gray-green peroxidase-positive bodies and giant lysosomes.Which of the following anomalies is associated with these findings?

Which of the following anomalies is morphologically similar to toxic granulation and is often seen in patients who have poor mucopolysaccharide degradation?

A benign condition has the following characteristics: WBC count of 45 × 10⁹/L with a left shift and normal RBC count.What is this condition?