Question 1

Regarding the CELL-DYN Sapphire,which parameter is determined by the impedance principle?

Accepted Answer

A) Hemoglobin 
B) Nucleated erythrocyte count 
C) Platelet count 
D) Total leukocyte count 
A) Hemoglobin 
B) Nucleated erythrocyte count 
C) Platelet count 
D) Total leukocyte count

Question 2

The Sysmex XE-2100 instrument printout reports a middle fluorescent ratio of 7.0 and a high fluorescent ratio of 1.3.What is the immature reticulocyte fraction?

Accepted Answer

A) 9.1 
B) 91.7 
C) 8.3 
D) 5.7 
A) 9.1 
B) 91.7 
C) 8.3 
D) 5.7

Question 3

Which of the following is a reported parameter for the ADVIA 120 but not for the 	LH 750 instrument?

Accepted Answer

A) RDW-CV 
B) Retic% 
C) CHCM 
D) MCVr 
A) RDW-CV 
B) Retic% 
C) CHCM 
D) MCVr

Question 4

Which parameter does the Coulter LH 750 instrument derive from a histogram?

Accepted Answer

A) Platelet count 
B) MCH 
C) Leukocyte count 
D) Hct 
A) Platelet count 
B) MCH 
C) Leukocyte count 
D) Hct

Question 5

Which instrument does not use fluorescence intensity in its determination of reticulocytes?

Accepted Answer

A) LH 750 
B) XE-2100 
C) ADVIA 120 
D) CELL-DYN Sapphire 
A) LH 750 
B) XE-2100 
C) ADVIA 120 
D) CELL-DYN Sapphire

Question 6

What is the principle of impedance?
 Name at least two instruments that employ this method for blood cell counting.

Accepted Answer

Impedance relies on the principle of inc

Question 7

Which of the following instruments uses both electromechanical and optical density as a means of clot detection?

Accepted Answer

A) STArt 4 Coagulation system 
B) BBL Fibrosystem 
C) Trinity Biotech Coag-A-Mate XM 
D) AMAX Destiny Plus 
A) STArt 4 Coagulation system 
B) BBL Fibrosystem 
C) Trinity Biotech Coag-A-Mate XM 
D) AMAX Destiny Plus

Question 8

What cellular characteristic is evaluated by radio frequency?

Accepted Answer

A) Size 
B) Density 
C) Shape 
D) Complexity 
A) Size 
B) Density 
C) Shape 
D) Complexity

Question 9

Which analyzer measures platelets in the same channel as reticulocytes?

Accepted Answer

A) Coulter Gen-S 
B) Sysmex XE-2100 
C) Advia 2120 
D) Trinity Biotech AMAX Destiny Plus 
A) Coulter Gen-S 
B) Sysmex XE-2100 
C) Advia 2120 
D) Trinity Biotech AMAX Destiny Plus

Question 10

Which parameter does the Sysmex XE-2100 instrument determine by using light-scattering and fluorescence intensity characteristics?

Accepted Answer

A) Platelet count 
B) Erythrocyte count 
C) Absolute basophil count 
D) Absolute lymphocyte count 
A) Platelet count 
B) Erythrocyte count 
C) Absolute basophil count 
D) Absolute lymphocyte count

Question 11

D-dimers are measured by which method on the Trinity Biotech AMAX Destiny Plus?

Accepted Answer

A) Electromechanical 
B) Optical density 
C) Chromogenic 
D) Immunologic 
A) Electromechanical 
B) Optical density 
C) Chromogenic 
D) Immunologic

Question 12

Which analyzer does not use cyanide-free detection of hemoglobin?

Accepted Answer

A) Advia 120 
B) Advia 2120 
C) Abbott Cell-Dyn Sapphire 
D) Sysmex XE-2100 
A) Advia 120 
B) Advia 2120 
C) Abbott Cell-Dyn Sapphire 
D) Sysmex XE-2100

Question 13

When using the CELL-DYN Sapphire to perform CBCs,a laboratory professional can choose to run the ImmunoPlt assay if:

Accepted Answer

A) Leukocyte count is decreased. 
B) Erythrocyte fragments are detected. 
C) Nucleated erythrocytes are observed. 
D) Erythrocyte count is increased. 
A) Leukocyte count is decreased. 
B) Erythrocyte fragments are detected. 
C) Nucleated erythrocytes are observed. 
D) Erythrocyte count is increased.

Question 14

Which instrument utilizes contour gating to classify different leukocyte cell types?

Accepted Answer

A) ADVIA 120 
B) XE-2100 
C) LH 750 
D) CELL-DYN Sapphire 
A) ADVIA 120 
B) XE-2100 
C) LH 750 
D) CELL-DYN Sapphire

Question 15

Which of the following instruments is capable of performing electromechanical,optical density,chromogenic,and immunologic methodologies?

Accepted Answer

A) STArt 4 
B) Destiny Plus 
C) STA Compact 
D) Coag-A-Mate XM 
A) STArt 4 
B) Destiny Plus 
C) STA Compact 
D) Coag-A-Mate XM

Question 16

In the reticulocyte determination,using the Sysmex XE-2100,the fluorescent dye containing oxazine and polymethine penetrates the cell membranes and stains the blood cells.What does the oxazine bind to within the cells?

Accepted Answer

A) Residual DNA 
B) Hemoglobin 
C) Residual RNA 
D) Mitochondria 
A) Residual DNA 
B) Hemoglobin 
C) Residual RNA 
D) Mitochondria

Question 17

Compare and contrast the methods of detection for the following analyzers:
a.Sysmex XE-2100
b.Abbott Cell-Dyn Sapphire
c.Coulter LH 780
d.Advia 2120

Accepted Answer

The answer of Compare and contrast the methods of detection...

Question 18

The principle that relies on detecting resistance as cells pass through a photo-detector and is used by most of the major hematology analyzers is:

Accepted Answer

A) Spectrophotometry 
B) Impedance 
C) Radio frequency 
D) MAPSS technology 
A) Spectrophotometry 
B) Impedance 
C) Radio frequency 
D) MAPSS technology

Exam 39: Automation in Hematology

Regarding the CELL-DYN Sapphire,which parameter is determined by the impedance principle?

The Sysmex XE-2100 instrument printout reports a middle fluorescent ratio of 7.0 and a high fluorescent ratio of 1.3.What is the immature reticulocyte fraction?

Which of the following is a reported parameter for the ADVIA 120 but not for the LH 750 instrument?

Which parameter does the Coulter LH 750 instrument derive from a histogram?

Which instrument does not use fluorescence intensity in its determination of reticulocytes?

What is the principle of impedance? Name at least two instruments that employ this method for blood cell counting.

Which of the following instruments uses both electromechanical and optical density as a means of clot detection?

What cellular characteristic is evaluated by radio frequency?

Which analyzer measures platelets in the same channel as reticulocytes?

Which parameter does the Sysmex XE-2100 instrument determine by using light-scattering and fluorescence intensity characteristics?

D-dimers are measured by which method on the Trinity Biotech AMAX Destiny Plus?

Which analyzer does not use cyanide-free detection of hemoglobin?

When using the CELL-DYN Sapphire to perform CBCs,a laboratory professional can choose to run the ImmunoPlt assay if:

Which instrument utilizes contour gating to classify different leukocyte cell types?

Which of the following instruments is capable of performing electromechanical,optical density,chromogenic,and immunologic methodologies?

In the reticulocyte determination,using the Sysmex XE-2100,the fluorescent dye containing oxazine and polymethine penetrates the cell membranes and stains the blood cells.What does the oxazine bind to within the cells?

Compare and contrast the methods of detection for the following analyzers: a.Sysmex XE-2100 b.Abbott Cell-Dyn Sapphire c.Coulter LH 780 d.Advia 2120

The principle that relies on detecting resistance as cells pass through a photo-detector and is used by most of the major hematology analyzers is:

Introduction

Cellular Homeostasis

Structure and Function of Hematopoietic Organs

Hematopoiesis

The Erythrocyte

Hemoglobin

Granulocytes and Monocytes

Lymphocytes

The Platelet

The Complete Blood Count and Peripheral Blood Smear Evaluation

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopathies: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Hypoproliferative Anemias

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Precursor Lymphoid Neoplasms

Mature Lymphoid Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology Laboratory

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hemostasis: Laboratory Testing and Instrumentation

Hematology Procedures

Bone Marrow Examination

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

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