Question 1

When native chromatin is digested with micrococcal nuclease,what significant result occurs?

Accepted Answer

DNA fragments of approximately 200 base pairs in length are formed.

Question 2

How does a polytene chromosome differ from a typical eukaryotic chromosome?

Accepted Answer

Polytene chromosomes are found in a variety of tissues in the larvae of some flies and several species of protozoans and plants.A polytene chromosome contains banding patterns and is large because of repeated replications of DNA without nuclear division.

Question 3

In E.coli,the genetic material is composed of ________.

Accepted Answer

A)  circular, double-stranded DNA 
B)  linear, double-stranded DNA 
C)  RNA and protein 
D)  circular, double-stranded RNA 
E)  polypeptide chains 
A)  circular, double-stranded DNA 
B)  linear, double-stranded DNA 
C)  RNA and protein 
D)  circular, double-stranded RNA 
E)  polypeptide chains A

Question 4

Briefly describe the makeup of VNTRs (variable number tandem repeats).

Accepted Answer

VNTRs are repeating DNA sequences of abo

Question 5

In contrast with euchromatin,heterochromatin contains more genes and is earlier replicating.

Accepted Answer

A) True 
 B)False

Question 6

What are histones,and how are they arranged in nucleosomes?

Accepted Answer

Histones include five main cla

Question 7

Viral genomes are always linear,double-stranded DNA.

Accepted Answer

A) True 
 B)False

Question 8

Briefly state what is meant by repetitive DNA.

Accepted Answer

DNA is present in re

Question 9

Although mutations have been observed in many different genes,they have not been isolated in histones.Why does this seem reasonable? If one wanted to produce antibodies to histones,would it be an easy task? Explain your answer.

Accepted Answer

Histones represent one of the most conse

Question 10

What is meant by SINE in terms of chromosome structure? By LINE? Why are they called "repetitive"?

Accepted Answer

SINE = short interspersed elem

Question 11

What is unusual about the amino acid composition of histones? How is the function of histones related to the amino acid composition? Of which histones are nucleosomes composed?

Accepted Answer

Histones contain large amounts of positi

Question 12

In instances in the eukaryotic genome,DNA sequences represent evolutionary vestiges of duplicated copies of genes.What are such regions called and what are their characteristics?

Accepted Answer

Pseudogenes are duplicated cop

Question 13

In situ hybridization allows one to "visualize" the location of labeled RNA or DNA in a tissue or cell.

Accepted Answer

A) True 
 B)False

Question 14

What similarities do bacterial chromosomes have with eukaryotic chromosomes?

Accepted Answer

Both have double-stranded DNA

Question 15

Chromosomal regions that represent evolutionary vestiges of duplicated copies of genes that have underdone sufficient mutations to render them untranscribable are called ________.

Accepted Answer

The answer of Chromosomal regions that represent evolutionary vestiges of...

Question 16

What are minisatellites and microsatellites?

Accepted Answer

Both are highly repe

Question 17

Compare and contrast the chromosome structure of viruses,bacteria,and eukaryotes.

Accepted Answer

The amount of DNA per structure (virus p

Question 18

Each human contains an identical set of VNTRs.

Accepted Answer

A) True 
 B)False

Question 19

Approximately how much of the mammalian genome is composed of repetitive DNA?

Accepted Answer

About 5% to 10% of a

Question 20

The E.coli chromosome is circular and double-stranded DNA.

Accepted Answer

A) True 
 B)False

Exam 12: DNA Organization in Chromosomes

When native chromatin is digested with micrococcal nuclease,what significant result occurs?

How does a polytene chromosome differ from a typical eukaryotic chromosome?

In E.coli,the genetic material is composed of ________.

Briefly describe the makeup of VNTRs (variable number tandem repeats).

In contrast with euchromatin,heterochromatin contains more genes and is earlier replicating.

What are histones,and how are they arranged in nucleosomes?

Viral genomes are always linear,double-stranded DNA.

Briefly state what is meant by repetitive DNA.

Although mutations have been observed in many different genes,they have not been isolated in histones.Why does this seem reasonable? If one wanted to produce antibodies to histones,would it be an easy task? Explain your answer.

What is meant by SINE in terms of chromosome structure? By LINE? Why are they called "repetitive"?

What is unusual about the amino acid composition of histones? How is the function of histones related to the amino acid composition? Of which histones are nucleosomes composed?

In instances in the eukaryotic genome,DNA sequences represent evolutionary vestiges of duplicated copies of genes.What are such regions called and what are their characteristics?

In situ hybridization allows one to "visualize" the location of labeled RNA or DNA in a tissue or cell.

What similarities do bacterial chromosomes have with eukaryotic chromosomes?

Chromosomal regions that represent evolutionary vestiges of duplicated copies of genes that have underdone sufficient mutations to render them untranscribable are called ________.

What are minisatellites and microsatellites?

Compare and contrast the chromosome structure of viruses,bacteria,and eukaryotes.

Each human contains an identical set of VNTRs.

Approximately how much of the mammalian genome is composed of repetitive DNA?

The E.coli chromosome is circular and double-stranded DNA.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Genetics

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Extranuclear Inheritance

DNA Structure and Analysis

DNA Replication and Recombination

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,dna Repair,and Transposition

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression in Eukaryotes

Developmental Genetics

Cancer and Regulation of the Cell Cycle

Recombinant DNA Technology

Genomics, bioinformatics, and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Neurogenetics

Population and Evolutionary Genetics

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