Question 1

The basic structure of a nucleotide includes ________.

Accepted Answer

A)  amino acids 
B)  tryptophan and leucine 
C)  base, sugar, and phosphate 
D)  mRNA, rRNA, and tRNA 
E)  phosphorus and sulfur 
A)  amino acids 
B)  tryptophan and leucine 
C)  base, sugar, and phosphate 
D)  mRNA, rRNA, and tRNA 
E)  phosphorus and sulfur C

Question 2

Regarding the structure of DNA,the covalently arranged combination of a deoxyribose and a nitrogenous base would be called a(n)________.

Accepted Answer

A)  nucleotide 
B)  ribonucleotide 
C)  monophosphate nucleoside 
D)  oligonucleotide 
E)  nucleoside 
A)  nucleotide 
B)  ribonucleotide 
C)  monophosphate nucleoside 
D)  oligonucleotide 
E)  nucleoside E

Question 3

In 1953,Watson and Crick published a paper that described the structure of DNA.

Accepted Answer

A) True 
 B)False  True

Question 4

At what approximate wavelengths do DNA,RNA,and proteins maximally absorb light?

Accepted Answer

260 nm,260

Question 5

Considering the structure of double-stranded DNA,which kind(s)of bonds hold one complementary strand to the other?

Accepted Answer

A)  ionic 
B)  covalent 
C)  van der Waals 
D)  hydrogen 
E)  hydrophobic and hydrophilic 
A)  ionic 
B)  covalent 
C)  van der Waals 
D)  hydrogen 
E)  hydrophobic and hydrophilic

Question 6

What are the two major components of the Tobacco Mosaic Virus?

Accepted Answer

A)  RNA and DNA 
B)  DNA and protein 
C)  RNA and protein 
D)  lipids and nucleic acids 
E)  carbohydrates and nucleic acids 
A)  RNA and DNA 
B)  DNA and protein 
C)  RNA and protein 
D)  lipids and nucleic acids 
E)  carbohydrates and nucleic acids

Question 7

What is meant by the term antiparallel?

Accepted Answer

The two chains in a double-str

Question 8

Suppose that the dinucleotide in the accompanying figure was cleaved with the enzyme spleen diesterase,which breaks the covalent bond connecting the phosphate to C-5′.After such cleavage,to which nucleoside is the phosphate now attached?

Accepted Answer

The answer of Suppose that the dinucleotide in the accompanying...

Question 9

List three forms of DNA.

Accepted Answer

A-DNA,B-DN

Question 10

In ribose,the 2′ C has an OH attached to it.

Accepted Answer

A) True 
 B)False

Question 11

The classic Hershey and Chase (1952)experiment that offered evidence in support of DNA being the genetic material in bacteriophages made use of which of the following labeled component(s)?

Accepted Answer

A)  phosphorus and sulfur 
B)  nitrogen and oxygen 
C)  tritium 
D)  hydrogen 
E)  None of the answers listed are correct. 
A)  phosphorus and sulfur 
B)  nitrogen and oxygen 
C)  tritium 
D)  hydrogen 
E)  None of the answers listed are correct.

Question 12

Is the accompanying figure DNA or RNA? ________ Is the arrow closest to the 5′ or 3′ end? ________ Spleen diesterase is an enzyme that breaks the covalent bond that connects the phosphate to the 5′ carbon.Assume that the dinucleotide is digested with spleen diesterase.To which base and to which carbon on the sugar is the phosphate now attached,A or T?

Accepted Answer

A)  DNA; 3′ end; T, 5′ 
B)  RNA; 3′ end; A, 3′ 
C)  DNA; 5′ end; A, 5′ 
D)  DNA; 3′ end; A, 3′ 
E)  RNA; 3′ end; T, 3′ 
A)  DNA; 3′ end; T, 5′ 
B)  RNA; 3′ end; A, 3′ 
C)  DNA; 5′ end; A, 5′ 
D)  DNA; 3′ end; A, 3′ 
E)  RNA; 3′ end; T, 3′

Question 13

Deoxyribonuclease is an enzyme that adds 3′-hydroxyl groups to RNA.

Accepted Answer

A) True 
 B)False

Question 14

If the GC content of a DNA molecule is 60%,what are the molar percentages of the four bases ?(G,C,T,A)?

Accepted Answer

G = 30%,C

Question 15

The base content of a sample of DNA is as follows: A = 31%,G = 31%,T = 19%,C = 19%.What conclusion can be drawn from this information?

Accepted Answer

The sample

Question 16

If 15% of the nitrogenous bases in a sample of DNA from a particular organism is thymine,what percentage should be cytosine?

Accepted Answer

A)  15% 
B)  30% 
C)  35% 
D)  40% 
E)  70% 
A)  15% 
B)  30% 
C)  35% 
D)  40% 
E)  70%

Question 17

Experiments conducted in the 1920s by Frederick Griffith involving the bacterium Diplococcus pneumoniae demonstrated that a substance from one bacterial strain could genetically transform other bacterial strains.What was the name of the substance capable of such transformation,and who finally determined its identity?

Accepted Answer

deoxyribon

Question 18

Considering the Central Dogma of Molecular Genetics,what general property is ascribed to DNA?

Accepted Answer

DNA makes

Question 19

What was the Avery et al.(1944)contribution to the understanding of molecular biology?

Accepted Answer

a demonstration that

Question 20

In the 1860s,a Swiss chemist,Friedrich Miescher,isolated an acidic substance from cell nuclei.What was the name of this substance,and what was its significance?

Accepted Answer

nuclein,co

Exam 10: DNA Structure and Analysis

The basic structure of a nucleotide includes ________.

Regarding the structure of DNA,the covalently arranged combination of a deoxyribose and a nitrogenous base would be called a(n)________.

In 1953,Watson and Crick published a paper that described the structure of DNA.

At what approximate wavelengths do DNA,RNA,and proteins maximally absorb light?

Considering the structure of double-stranded DNA,which kind(s)of bonds hold one complementary strand to the other?

What are the two major components of the Tobacco Mosaic Virus?

What is meant by the term antiparallel?

Suppose that the dinucleotide in the accompanying figure was cleaved with the enzyme spleen diesterase,which breaks the covalent bond connecting the phosphate to C-5′.After such cleavage,to which nucleoside is the phosphate now attached?

List three forms of DNA.

In ribose,the 2′ C has an OH attached to it.

The classic Hershey and Chase (1952)experiment that offered evidence in support of DNA being the genetic material in bacteriophages made use of which of the following labeled component(s)?

Deoxyribonuclease is an enzyme that adds 3′-hydroxyl groups to RNA.

If the GC content of a DNA molecule is 60%,what are the molar percentages of the four bases ?(G,C,T,A)?

The base content of a sample of DNA is as follows: A = 31%,G = 31%,T = 19%,C = 19%.What conclusion can be drawn from this information?

If 15% of the nitrogenous bases in a sample of DNA from a particular organism is thymine,what percentage should be cytosine?

Considering the Central Dogma of Molecular Genetics,what general property is ascribed to DNA?

What was the Avery et al.(1944)contribution to the understanding of molecular biology?

In the 1860s,a Swiss chemist,Friedrich Miescher,isolated an acidic substance from cell nuclei.What was the name of this substance,and what was its significance?

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Genetics

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Extranuclear Inheritance

DNA Replication and Recombination

DNA Organization in Chromosomes

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,dna Repair,and Transposition

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression in Eukaryotes

Developmental Genetics

Cancer and Regulation of the Cell Cycle

Recombinant DNA Technology

Genomics, bioinformatics, and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Neurogenetics

Population and Evolutionary Genetics

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