Question 1

Present an overview of the research dealing with the genetics of behavior in small mammals (mice or rats)and Drosophila.

Accepted Answer

mice or rats: fear and anxiety,Huntington disease; Drosophila: geo- and phototaxis and single gene influences such as those relating to courtship and mating,learning and memory

Question 2

Individuals with Huntington disease have a point mutation in a gene coding for the p53 protein.

Accepted Answer

A) True 
 B)False  False

Question 3

How are electrical impulses propagated from neuron to neuron?

Accepted Answer

Impulses are propagated by the transport of sodium and potassium ions across the plasma membrane of the neuron.

Question 4

Briefly describe the mutant status of the HD gene.

Accepted Answer

The HD gene encodes a 350 kd protein (hu

Question 5

Fragile X syndrome is a neurological disorder that is caused by a dominantly inherited mutant allele on the X chromosome?

Accepted Answer

In fragile X syndrome there is

Question 6

What is the biochemical role of adenyl cyclase?

Accepted Answer

Adenyl cyclase converts ATP to cAMP whic

Question 7

Autism spectrum disorders are neurodevelopmental disorders that appear to be ________.

Accepted Answer

A)  caused by a single dominant gene 
B)  multifactorial and complex in nature with a genetic component 
C)  caused by several genes located on the X chromosome 
D)  caused by a low number of recessive genes located mainly on the autosomes 
E)  directly related to trinucleotide repeat increases but not decreases 
A)  caused by a single dominant gene 
B)  multifactorial and complex in nature with a genetic component 
C)  caused by several genes located on the X chromosome 
D)  caused by a low number of recessive genes located mainly on the autosomes 
E)  directly related to trinucleotide repeat increases but not decreases

Question 8

The HD gene,one of the first genes to be mapped in humans by RFLP,is located on the short arm of chromosome 4.It codes for ________.

Accepted Answer

a large pr

Question 9

A transgenic mouse model now exists for Huntington disease in humans.

Accepted Answer

A) True 
 B)False

Question 10

Mitochondrial ribosomes are responsible for determining the learning and memory development in Drosophila.

Accepted Answer

A) True 
 B)False

Question 11

Drosophila can learn and remember.

Accepted Answer

A) True 
 B)False

Question 12

Much effort has been expended to understand genetic involvement in brain function in Drosophila.Why might this research be important in understanding the functioning of the human brain?

Accepted Answer

Mammalian homologs o

Question 13

Recent research using gene expression profiles indicates that schizophrenia and autism spectrum disorders are ________.

Accepted Answer

A)  like opposite sides of the same coin 
B)  identical at the molecular level 
C)  completely unrelated 
D)  likely to be caused by the same dominant gene 
E)  likely to be caused by the same recessive gene 
A)  like opposite sides of the same coin 
B)  identical at the molecular level 
C)  completely unrelated 
D)  likely to be caused by the same dominant gene 
E)  likely to be caused by the same recessive gene

Question 14

Evidence from genome-wide association studies on schizophrenia indicates that no single gene or allele makes a significant contribution to this disorder.

Accepted Answer

A) True 
 B)False

Question 15

List at least three areas of research that deal with the genetics of behavior in humans.

Accepted Answer

Huntington

Question 16

Suggest two problems with determining the genetic basis of a behavioral trait in humans.

Accepted Answer

influence of the env

Question 17

How would the use of a large series of monozygotic and dizygotic twins enhance studies on the genetic basis of human behavior?

Accepted Answer

Monozygotic twins are genetically identi

Question 18

The symptoms of Huntington disease usually appear in the third to fifth decade of life in humans.

Accepted Answer

A) True 
 B)False

Question 19

Humans are relatively unavailable as experimental subjects in genetic investigations,yet considerable interest surrounds intelligence,language,personality,and emotional behaviors.One difficulty in studying such behaviors is the high likelihood that they ________.

Accepted Answer

A)  are strongly influenced by birth order and diet 
B)  are affected by the environment 
C)  follow non-Mendelian patterns of inheritance 
D)  follow extranuclear patterns of inheritance 
E)  have no likely genetic influence 
A)  are strongly influenced by birth order and diet 
B)  are affected by the environment 
C)  follow non-Mendelian patterns of inheritance 
D)  follow extranuclear patterns of inheritance 
E)  have no likely genetic influence

Question 20

In studies attempting to determine a genetic basis for a given behavior,if the environment is held constant,and behavioral differences directly correlate with genetic differences,a genetic basis for the behavioral state is supported.

Accepted Answer

A) True 
 B)False

Exam 24: Neurogenetics

Present an overview of the research dealing with the genetics of behavior in small mammals (mice or rats)and Drosophila.

Individuals with Huntington disease have a point mutation in a gene coding for the p53 protein.

How are electrical impulses propagated from neuron to neuron?

Briefly describe the mutant status of the HD gene.

Fragile X syndrome is a neurological disorder that is caused by a dominantly inherited mutant allele on the X chromosome?

What is the biochemical role of adenyl cyclase?

Autism spectrum disorders are neurodevelopmental disorders that appear to be ________.

The HD gene,one of the first genes to be mapped in humans by RFLP,is located on the short arm of chromosome 4.It codes for ________.

A transgenic mouse model now exists for Huntington disease in humans.

Mitochondrial ribosomes are responsible for determining the learning and memory development in Drosophila.

Drosophila can learn and remember.

Much effort has been expended to understand genetic involvement in brain function in Drosophila.Why might this research be important in understanding the functioning of the human brain?

Recent research using gene expression profiles indicates that schizophrenia and autism spectrum disorders are ________.

Evidence from genome-wide association studies on schizophrenia indicates that no single gene or allele makes a significant contribution to this disorder.

List at least three areas of research that deal with the genetics of behavior in humans.

Suggest two problems with determining the genetic basis of a behavioral trait in humans.

How would the use of a large series of monozygotic and dizygotic twins enhance studies on the genetic basis of human behavior?

The symptoms of Huntington disease usually appear in the third to fifth decade of life in humans.

Humans are relatively unavailable as experimental subjects in genetic investigations,yet considerable interest surrounds intelligence,language,personality,and emotional behaviors.One difficulty in studying such behaviors is the high likelihood that they ________.

In studies attempting to determine a genetic basis for a given behavior,if the environment is held constant,and behavioral differences directly correlate with genetic differences,a genetic basis for the behavioral state is supported.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Genetics

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Extranuclear Inheritance

DNA Structure and Analysis

DNA Replication and Recombination

DNA Organization in Chromosomes

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,dna Repair,and Transposition

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression in Eukaryotes

Developmental Genetics

Cancer and Regulation of the Cell Cycle

Recombinant DNA Technology

Genomics, bioinformatics, and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Population and Evolutionary Genetics

Filters