Question 1

T independent activation of B cells usually requires which of the following?

Accepted Answer

A)  An internal protein antigen. 
B)  Dendritic cell activation of the B cell. 
C)  A highly repetitive antigen like some polysaccharides. 
D)  Macrophage activation of the B cell. 
E)  Toll-like receptor activation of the B cell. 
A)  An internal protein antigen. 
B)  Dendritic cell activation of the B cell. 
C)  A highly repetitive antigen like some polysaccharides. 
D)  Macrophage activation of the B cell. 
E)  Toll-like receptor activation of the B cell.

Question 2

CD4⁺ T cells can be activated by binding soluble antigen.

Accepted Answer

A) True 
 B)False

Question 3

Which of these is able to bind to T cell receptors on a specific T cell?

Accepted Answer

A)  Any epitope on an antigen. 
B)  Any epitope. 
C)  Any antigen. 
D)  Only a single unique epitope on an antigen. 
E)  Any ligand. 
A)  Any epitope on an antigen. 
B)  Any epitope. 
C)  Any antigen. 
D)  Only a single unique epitope on an antigen. 
E)  Any ligand.

Question 4

CD4⁺ T cells are activated through binding to specific antigen presented by the MHC II molecules on the surface of a dendritic cell.

Accepted Answer

A) True 
 B)False

Question 5

Some B cells are able to be activated by certain antigens without the help of a T-helper cell.

Accepted Answer

A) True 
 B)False

Question 6

Dendritic cells are able to activate both naïve CD4⁺ and naïve CD8⁺ T cells.

Accepted Answer

A) True 
 B)False

Question 7

CD8⁺ T cells are activated through TCR-binding to a specific antigen presented by the MHC II molecules on the surface of a macrophage.

Accepted Answer

A) True 
 B)False

Question 8

Immunoglobulin M (IgM)has ___________ antigen binding sites.

Accepted Answer

A)  two 
B) four 
C)  six 
D)  eight 
E)  ten 
A)  two 
B) four 
C)  six 
D)  eight 
E)  ten

Question 9

Which antibody is involved in the initiation of anaphylactic or allergic reactions?

Accepted Answer

A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM 
A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM

Question 10

Every time an antigen is encountered the immune memory response increases.

Accepted Answer

A) True 
 B)False

Question 11

The spleen is an example of a secondary lymphoid tissue.

Accepted Answer

A) True 
 B)False

Question 12

Which of these is the major antibody present in serum?

Accepted Answer

A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM 
A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM

Question 13

TH1 cells function in which of these processes?

Accepted Answer

A)  The humoral immune response. 
B)  The cell-mediated immune response. 
C)  The innate immune response. 
D)  The production of antibody. 
E)  The activation of complement by antigen-antibody complex. 
A)  The humoral immune response. 
B)  The cell-mediated immune response. 
C)  The innate immune response. 
D)  The production of antibody. 
E)  The activation of complement by antigen-antibody complex.

Question 14

TH1 cells play an important role in the cell-mediated immune response.

Accepted Answer

A) True 
 B)False

Question 15

Antibodies protect the host from infections by performing all of the following activities except one.Select the activity it does NOT perform.

Accepted Answer

A)  antigen degradation 
B)  complement activation 
C)  agglutination 
D)  opsonization 
E)  ADCC killing of infected cells by NK cells 
A)  antigen degradation 
B)  complement activation 
C)  agglutination 
D)  opsonization 
E)  ADCC killing of infected cells by NK cells

Question 16

Which of these is NOT a function of dendritic cells?

Accepted Answer

A)  Activate naïve CD4⁺ T cells. 
B)  Activate naïve CD8⁺ T cells. 
C)  Function as a "professional" phagocyte. 
D)  Activate effector CD4⁺ T cells 
E)  Activate memory CD4⁺ T cells. 
A)  Activate naïve CD4⁺ T cells. 
B)  Activate naïve CD8⁺ T cells. 
C)  Function as a "professional" phagocyte. 
D)  Activate effector CD4⁺ T cells 
E)  Activate memory CD4⁺ T cells.

Question 17

What is the effector function of CD8⁺ cells?

Accepted Answer

A)  Stimulation of B-cells for antibody production. 
B)  Antibody production. 
C)  The cytotoxic killing of infected cells. 
D)  Stimulation of macrophages. 
E)  Stimulation of dendritic cells. 
A)  Stimulation of B-cells for antibody production. 
B)  Antibody production. 
C)  The cytotoxic killing of infected cells. 
D)  Stimulation of macrophages. 
E)  Stimulation of dendritic cells.

Question 18

Antigen-presenting cells infected by a virus can present processed viral antigen on their surface to T cells through these.

Accepted Answer

A)  MHC I molecules 
B)  MHC II molecules 
C)  interleukin 2 molecules 
D)  tumor necrosis factor alpha 
E)  interferon gamma 
A)  MHC I molecules 
B)  MHC II molecules 
C)  interleukin 2 molecules 
D)  tumor necrosis factor alpha 
E)  interferon gamma

Question 19

Describe how an endogenous antigen is processed and displayed on an antigen presenting cell.

Accepted Answer

Endogenous antigens are processed and di

Question 20

Which of these could be accomplished with an ELISA (enzyme-linked immunosorbent assay)?

Accepted Answer

A)  Detection of specific antibodies in serum. 
B)  Separation of B cells from T cells. 
C)  Identification of the classes of antibodies present in serum. 
D)  Identification of antigens on various pathogens. 
E)  Agglutination of red blood cells. 
A)  Detection of specific antibodies in serum. 
B)  Separation of B cells from T cells. 
C)  Identification of the classes of antibodies present in serum. 
D)  Identification of antigens on various pathogens. 
E)  Agglutination of red blood cells.

Exam 20: Adaptive Immunity

T independent activation of B cells usually requires which of the following?

CD4⁺ T cells can be activated by binding soluble antigen.

Which of these is able to bind to T cell receptors on a specific T cell?

CD4⁺ T cells are activated through binding to specific antigen presented by the MHC II molecules on the surface of a dendritic cell.

Some B cells are able to be activated by certain antigens without the help of a T-helper cell.

Dendritic cells are able to activate both naïve CD4⁺ and naïve CD8⁺ T cells.

CD8⁺ T cells are activated through TCR-binding to a specific antigen presented by the MHC II molecules on the surface of a macrophage.

Immunoglobulin M (IgM)has ___________ antigen binding sites.

Which antibody is involved in the initiation of anaphylactic or allergic reactions?

Every time an antigen is encountered the immune memory response increases.

The spleen is an example of a secondary lymphoid tissue.

Which of these is the major antibody present in serum?

TH1 cells function in which of these processes?

TH1 cells play an important role in the cell-mediated immune response.

Antibodies protect the host from infections by performing all of the following activities except one.Select the activity it does NOT perform.

Which of these is NOT a function of dendritic cells?

What is the effector function of CD8⁺ cells?

Antigen-presenting cells infected by a virus can present processed viral antigen on their surface to T cells through these.

Describe how an endogenous antigen is processed and displayed on an antigen presenting cell.

Which of these could be accomplished with an ELISA (enzyme-linked immunosorbent assay)?

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