Question 1

Which of the following terms describes the phenomenon of genes occurring in the same order on a chromosome in two different species?

Accepted Answer

A) heterochrony 
B) neoteny 
C) synteny 
D) phylogeny 
A) heterochrony 
B) neoteny 
C) synteny 
D) phylogeny

Question 2

There are five major types of histone proteins,but only four of them are considered as core histones.Which one of the following is NOT considered a core histone protein?

Accepted Answer

A) H1 
B) H2B 
C) H3 
D) H4 
A) H1 
B) H2B 
C) H3 
D) H4

Question 3

The karyotype for any particular species is characterized by

Accepted Answer

A) the number of metaphase chromosomes. 
B) the size and shape of the metaphase chromosomes. 
C) the banding pattern of the metaphase chromosomes. 
D) all of the above 
A) the number of metaphase chromosomes. 
B) the size and shape of the metaphase chromosomes. 
C) the banding pattern of the metaphase chromosomes. 
D) all of the above

Question 4

All the following statements about heterochromatin except:

Accepted Answer

A) It is a dark-staining area of a chromosome. 
B) It is usually transcriptionally active. 
C) It is often simple sequences of DNA. 
D) It is a region of condensed chromatin. 
A) It is a dark-staining area of a chromosome. 
B) It is usually transcriptionally active. 
C) It is often simple sequences of DNA. 
D) It is a region of condensed chromatin.

Question 5

In eukaryotes,tandemly repeated genes encode

Accepted Answer

A) rRNAs. 
B) cytoskeletal proteins. 
C) β-globin. 
D) all of the above 
A) rRNAs. 
B) cytoskeletal proteins. 
C) β-globin. 
D) all of the above

Question 6

In mammals,X-chromosome inactivation

Accepted Answer

A) occurs in half the diploid cells of the adult female. 
B) results from the ionization of the X-chromosome. 
C) is considered an epigenetic event. 
D) b and c 
A) occurs in half the diploid cells of the adult female. 
B) results from the ionization of the X-chromosome. 
C) is considered an epigenetic event. 
D) b and c

Question 7

The DNA and protein sequences of the α-tubulin genes in humans and in fish are similar,and because each arose due to speciation,these genes would be considered:

Accepted Answer

A) homologous. 
B) orthologous. 
C) paralogous. 
D) autologous. 
A) homologous. 
B) orthologous. 
C) paralogous. 
D) autologous.

Question 8

Describe the two major pathways for transposition of mobile elements.

Accepted Answer

Mobile elements fall into two major clas

Question 9

Which of the following classes of repetitive DNA is most abundant in the human genome?

Accepted Answer

A) simple-sequence DNA 
B) non-LTR transposons 
C) LTR transposons 
D) DNA transposons 
A) simple-sequence DNA 
B) non-LTR transposons 
C) LTR transposons 
D) DNA transposons

Question 10

What is the advantage of complex transcription units over simple transcription units?

Accepted Answer

A complex transcription unit can encode

Question 11

Which of the following organisms has the greatest amount of DNA per cell?

Accepted Answer

A) chicken 
B) fruit fly 
C) tulip 
D) human 
A) chicken 
B) fruit fly 
C) tulip 
D) human

Question 12

All the following statements about complex transcription units are true except:

Accepted Answer

A) They can have multiple poly(
A) sites. 
B) They can generate multiple mRNAs. 
C) They can generate multiple polypeptides. 
D) They are common in bacteria. 
A) They can have multiple poly(
A) sites. 
B) They can generate multiple mRNAs. 
C) They can generate multiple polypeptides. 
D) They are common in bacteria.

Question 13

Which of the following statement(s)is (are)true of a eukaryotic chromosome?

Accepted Answer

A) It is a linear structure. 
B) It consists of a single DNA molecule. 
C) It can contain greater than a billion base pairs of DNA. 
D) all of the above 
A) It is a linear structure. 
B) It consists of a single DNA molecule. 
C) It can contain greater than a billion base pairs of DNA. 
D) all of the above

Question 14

Which of the following lines of evidence is indicative of the presence of a gene in an unknown DNA sequence?

Accepted Answer

A) alignment to a partial cDNA sequence 
B) sequence similarity to genes of other organisms 
C) ORF consistent with the rules for exon and intron sequences 
D) all of the above 
A) alignment to a partial cDNA sequence 
B) sequence similarity to genes of other organisms 
C) ORF consistent with the rules for exon and intron sequences 
D) all of the above

Question 15

Drosophila is considered a model system because it is quite easy to create transgenic lines harboring a variety of different genes.As a Drosophila geneticist,which one of the following is a DNA transposon that you would exploit to create a transgenic line?

Accepted Answer

A) copia element 
B) N element 
C) P element 
D) Ty element 
A) copia element 
B) N element 
C) P element 
D) Ty element

Question 16

What is the underlying mechanism behind why gene mutations that lead to Huntington's disease act as dominant mutations?

Accepted Answer

The mutations that lead to Huntington's

Question 17

DNA that is transcriptionally active

Accepted Answer

A) is more susceptible to DNase I digestion. 
B) is tightly packed into a solenoid arrangement. 
C) contains nonacetylated histones. 
D) is more condensed than nontranscribed DNA. 
A) is more susceptible to DNase I digestion. 
B) is tightly packed into a solenoid arrangement. 
C) contains nonacetylated histones. 
D) is more condensed than nontranscribed DNA.

Question 18

Chromosome painting involves

Accepted Answer

A) staining chromosomes with Giemsa reagent. 
B) hybridizing fluorescent probes to chromosomes. 
C) hybridizing radioactive probes to chromosomes. 
D) a and b 
A) staining chromosomes with Giemsa reagent. 
B) hybridizing fluorescent probes to chromosomes. 
C) hybridizing radioactive probes to chromosomes. 
D) a and b

Question 19

Blood samples were retrieved from a crime scene,and three suspects were arrested on suspicion of committing the crime.Which of the following techniques could be used to identify the suspect(s)responsible for crime?

Accepted Answer

A) DNA fingerprinting 
B) polymerase chain reaction 
C) in situ hybridization 
D) DNA fingerprinting and polymerase chain reaction 
A) DNA fingerprinting 
B) polymerase chain reaction 
C) in situ hybridization 
D) DNA fingerprinting and polymerase chain reaction

Question 20

Describe the general organization of protein coding genes in the yeast and human genomes.

Accepted Answer

In yeast,the protein coding regions are

Exam 7: Genes Genomics and Chromosomes

Which of the following terms describes the phenomenon of genes occurring in the same order on a chromosome in two different species?

There are five major types of histone proteins,but only four of them are considered as core histones.Which one of the following is NOT considered a core histone protein?

The karyotype for any particular species is characterized by

All the following statements about heterochromatin except:

In eukaryotes,tandemly repeated genes encode

In mammals,X-chromosome inactivation

The DNA and protein sequences of the α-tubulin genes in humans and in fish are similar,and because each arose due to speciation,these genes would be considered:

Describe the two major pathways for transposition of mobile elements.

Which of the following classes of repetitive DNA is most abundant in the human genome?

What is the advantage of complex transcription units over simple transcription units?

Which of the following organisms has the greatest amount of DNA per cell?

All the following statements about complex transcription units are true except:

Which of the following statement(s)is (are)true of a eukaryotic chromosome?

Which of the following lines of evidence is indicative of the presence of a gene in an unknown DNA sequence?

Drosophila is considered a model system because it is quite easy to create transgenic lines harboring a variety of different genes.As a Drosophila geneticist,which one of the following is a DNA transposon that you would exploit to create a transgenic line?

What is the underlying mechanism behind why gene mutations that lead to Huntington's disease act as dominant mutations?

DNA that is transcriptionally active

Chromosome painting involves

Blood samples were retrieved from a crime scene,and three suspects were arrested on suspicion of committing the crime.Which of the following techniques could be used to identify the suspect(s)responsible for crime?

Describe the general organization of protein coding genes in the yeast and human genomes.

Chemical Foundations

Molecular Genetic Techniques

Protein Structure and Function

Culturing and Visualizing Cells

Fundamental Molecular Genetic Mechanisms

Bio-membrane Structure

Transcriptional Control of Gene Expression

Post-Transcriptional Gene Control

Transmembrane Transport of Ions and Small Molecules

Cellular Energetics

Moving Proteins Into Membranes and Organelles

Vesicular Traffic, Secretion, and Endocytosis

Signal Transduction and G-Protein Coupled Receptors

Signaling Pathways That Control Gene Activity

Cell Organization and Movement I: Microfilaments

Cell Organization and Movement II: Microtubules and Intermediate Filaments

Regulating the Eukaryotic Cell Cycle

Integrating Cells Into Tissues

Cell Birth, Lineage, and Death

Nerve Cells

Immunology

Cancer

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