Question 1

What motor protein generates the force to cause axoneme bending?

Accepted Answer

Outer arm axonemal dynein gene

Question 2

At MTOCs,microtubule nucleation is facilitated by:

Accepted Answer

A) centrioles. 
B) γ-tubulin. 
C) GDP-tubulin dimers. 
D) basal bodies. 
A) centrioles. 
B) γ-tubulin. 
C) GDP-tubulin dimers. 
D) basal bodies.

Question 3

The EB1 protein has several functions.Which of the following is/are true regarding EB1?

Accepted Answer

A) It promotes microtubule growth by enhancing polymerization at the (+)end. 
B) Other microtubule plus-end tracking proteins use EB1 to "hitchhike" onto the growing microtubule. 
C) It can bind further back from the blunt end of microtubules. 
D) all of the above 
A) It promotes microtubule growth by enhancing polymerization at the (+)end. 
B) Other microtubule plus-end tracking proteins use EB1 to "hitchhike" onto the growing microtubule. 
C) It can bind further back from the blunt end of microtubules. 
D) all of the above

Question 4

Microtubule assembly requires:

Accepted Answer

A) microtubule-associated proteins. 
B) incubation at 4°C. 
C) ATP. 
D) a tubulin concentration in excess of the Cc. 
A) microtubule-associated proteins. 
B) incubation at 4°C. 
C) ATP. 
D) a tubulin concentration in excess of the Cc.

Question 5

Capture of microtubule (+)ends by chromosomes occurs during:

Accepted Answer

A) metaphase. 
B) prometaphase. 
C) anaphase. 
D) telophase. 
A) metaphase. 
B) prometaphase. 
C) anaphase. 
D) telophase.

Question 6

In studies of wound healing,it was noticed that when the cells at the edge are induced to polarize and move to fill the wound,the Golgi complex moves to the front of the nucleus toward the cell front.What is the purpose of this reorientation and how is it accomplished?

Accepted Answer

Cdc42 activation at the front of the cel

Question 7

Kinetochores assemble at the:

Accepted Answer

A) centrosome. 
B) spindle pole. 
C) telomere. 
D) centromere. 
A) centrosome. 
B) spindle pole. 
C) telomere. 
D) centromere.

Question 8

During late anaphase and telophase,the microfilament-based contractile ring facilitates pinching the cell into two,but the ring must first be positioned equidistant between the two spindle poles before this occurs.Describe the mechanism whereby signals from the spindle direct the positioning of the contractile ring.

Accepted Answer

The chromosome passenger complex (CPC)is

Question 9

Which of the following occurs during anaphase A?

Accepted Answer

A) The spindle elongates. 
B) Kinetochores remain attached to shortening kinetochore microtubules. 
C) Chromosomes move to the spindle equator. 
D) The spindle poles move closer together. 
A) The spindle elongates. 
B) Kinetochores remain attached to shortening kinetochore microtubules. 
C) Chromosomes move to the spindle equator. 
D) The spindle poles move closer together.

Question 10

Which of the following is true regarding the transport of cargo by cytoplasmic dynein?

Accepted Answer

A) Dynactin is the protein that links dynein to microtubules. 
B) Transport is toward the (+)end of the microtubules. 
C) GTP binds to the head region of dynein. 
D) LIS1 associates with the head region of dynein to facilitate transport. 
A) Dynactin is the protein that links dynein to microtubules. 
B) Transport is toward the (+)end of the microtubules. 
C) GTP binds to the head region of dynein. 
D) LIS1 associates with the head region of dynein to facilitate transport.

Question 11

In most cells,where do all microtubules originate?

Accepted Answer

In most cells,microtubules ori

Question 12

What is the role of the basal body in generating axoneme structure?

Accepted Answer

The basal body is a bundle of nine tripl

Question 13

What function do kinetochore-bound motor proteins perform during anaphase A?

Accepted Answer

During anaphase A,kinetochore-

Question 14

In cells,the γ-tubulin ring complex is found:

Accepted Answer

A) in the hollow core of the microtubule. 
B) at the microtubule (−)end. 
C) at the microtubule (+)end. 
D) along the outer wall of the microtubule. 
A) in the hollow core of the microtubule. 
B) at the microtubule (−)end. 
C) at the microtubule (+)end. 
D) along the outer wall of the microtubule.

Question 15

The force for axoneme bending is derived from the:

Accepted Answer

A) sliding movement of central pair microtubules. 
B) contraction of central pair microtubules. 
C) sliding movement of outer doublet microtubules. 
D) contraction of outer doublet microtubules. 
A) sliding movement of central pair microtubules. 
B) contraction of central pair microtubules. 
C) sliding movement of outer doublet microtubules. 
D) contraction of outer doublet microtubules.

Question 16

Where are microtubules observed to be present in different polarities?

Accepted Answer

A) axons of nerve cells 
B) animal cells in interphase 
C) animal cells in mitosis 
D) dendrites of nerve cells 
A) axons of nerve cells 
B) animal cells in interphase 
C) animal cells in mitosis 
D) dendrites of nerve cells

Question 17

A microtubule protofilament is formed by the:

Accepted Answer

A) lateral association of only γ-tubulin subunits. 
B) head-to-tail association of only γ-tubulin subunits. 
C) lateral association of tubulin dimers. 
D) head-to-tail association of tubulin dimers. 
A) lateral association of only γ-tubulin subunits. 
B) head-to-tail association of only γ-tubulin subunits. 
C) lateral association of tubulin dimers. 
D) head-to-tail association of tubulin dimers.

Question 18

Why would neuronal vesicles probably contain both kinesin and cytosolic dynein?

Accepted Answer

Neuronal vesicles may contain both motor

Question 19

Which of the following is true about intermediate filaments?

Accepted Answer

A) They are named based on their location in cells between actin microfilaments and microtubules. 
B) All cells express the same class II cytoplasmic intermediate filament proteins. 
C) Staggered,antiparallel tetramers give intermediate filaments strength. 
D) Acidic and basic keratins provide dynamic paths on which organelles may travel. 
A) They are named based on their location in cells between actin microfilaments and microtubules. 
B) All cells express the same class II cytoplasmic intermediate filament proteins. 
C) Staggered,antiparallel tetramers give intermediate filaments strength. 
D) Acidic and basic keratins provide dynamic paths on which organelles may travel.

Question 20

In the mitotic spindle,astral microtubules function to:

Accepted Answer

A) connect the spindle poles. 
B) attach chromosomes to the spindle. 
C) carry out cytokinesis. 
D) anchor the spindle poles to the plasma membrane. 
A) connect the spindle poles. 
B) attach chromosomes to the spindle. 
C) carry out cytokinesis. 
D) anchor the spindle poles to the plasma membrane.

Exam 17: Cell Organization and Movement II: Microtubules and Intermediate Filaments

What motor protein generates the force to cause axoneme bending?

At MTOCs,microtubule nucleation is facilitated by:

The EB1 protein has several functions.Which of the following is/are true regarding EB1?

Microtubule assembly requires:

Capture of microtubule (+)ends by chromosomes occurs during:

In studies of wound healing,it was noticed that when the cells at the edge are induced to polarize and move to fill the wound,the Golgi complex moves to the front of the nucleus toward the cell front.What is the purpose of this reorientation and how is it accomplished?

Kinetochores assemble at the:

Which of the following occurs during anaphase A?

Which of the following is true regarding the transport of cargo by cytoplasmic dynein?

In most cells,where do all microtubules originate?

What is the role of the basal body in generating axoneme structure?

What function do kinetochore-bound motor proteins perform during anaphase A?

In cells,the γ-tubulin ring complex is found:

The force for axoneme bending is derived from the:

Where are microtubules observed to be present in different polarities?

A microtubule protofilament is formed by the:

Why would neuronal vesicles probably contain both kinesin and cytosolic dynein?

Which of the following is true about intermediate filaments?

In the mitotic spindle,astral microtubules function to:

Chemical Foundations

Molecular Genetic Techniques

Protein Structure and Function

Culturing and Visualizing Cells

Fundamental Molecular Genetic Mechanisms

Bio-membrane Structure

Genes Genomics and Chromosomes

Transcriptional Control of Gene Expression

Post-Transcriptional Gene Control

Transmembrane Transport of Ions and Small Molecules

Cellular Energetics

Moving Proteins Into Membranes and Organelles

Vesicular Traffic, Secretion, and Endocytosis

Signal Transduction and G-Protein Coupled Receptors

Signaling Pathways That Control Gene Activity

Cell Organization and Movement I: Microfilaments

Regulating the Eukaryotic Cell Cycle

Integrating Cells Into Tissues

Cell Birth, Lineage, and Death

Nerve Cells

Immunology

Cancer

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