Exam 11: Single-Gene Inheritance and Meiosis Rock for a Cause

A man who is a carrier for cystic fibrosis and for the TGFB1 modifier gene has a child with a woman who is also a carrier for cystic fibrosis but has two copies of the recessive allele for the TGFB1 modifier.What percentage of their children will have cystic fibrosis AND express the recessive modifier? Show your Punnett square.

Explain how males inherit more DNA from their mothers than from their fathers.

A carrier is someone who

Would a change in the nucleotide sequence of DNA change the structure of a protein?

Explain how someone's parents are healthy despite carrying a copy of a defective CF-associated gene?

All of the following are true of alleles,EXCEPT

How is the sequence of amino acids in a protein determined?

Sister chromatids are held together at the

Explain how a child inherits exactly half of his or her chromosomes from each parent.

Explain the role of a modifier gene.

What is a phenotype?

How can someone get two different alleles of the same gene?

Meiosis differs from mitosis in all of the following ways,EXCEPT

Albinism is a recessively inherited condition.What is the probability that a child will be born with albinism if the child's mother is albino,the child's father has normal pigmentation,and the child's paternal grandmother was albino? Use a Punnett square to show your work and use the letters "A" and "a" to designate dominant and recessive alleles,respectively.

Explain the terms dominant and recessive.Use the concepts of phenotype and genotype in your explanation.

A phenotypically normal woman marries a man with Wilson disease,a autosomal recessive disorder.They have a son who has Wilson disease.If you need two copies of the recessive allele to be affected and the mother doesn't have the disease,how did the son get it?

Name at least three ways in which meiosis differs from mitosis.

Two normal individuals have a child who has cystic fibrosis,an autosomal recessive disease.How did this happen?

Define the term genotype.