Exam 12: Gene Mutation

The parents-to-be were shocked when an ultrasound scan done in the second trimester of the pregnancy showed a fetus with obviously broken leg bones and ribs.The doctor diagnosed osteogenesis imperfecta.This is caused by a mutation in a gene that encodes

The spontaneous mutation rate for autosomal genes can be estimated using the formula: number of de novo cases/_____X.3-26-2013

A point mutation alters

Different disease phenotypes caused by mutations in the same gene are termed allelic disorders.

Estimates of spontaneous mutation rates are made using dominant disorders because

The fact that myotonic dystrophy worsens with each generation is due to

Allelic disorders may result from mutations in different parts of the same gene.

A researcher might use site-directed mutagenesis because

A source of gamma radiation is

Fragile X syndrome is caused by a(n)

A tautomer is

Which of the following disorders does not involve faulty DNA repair?

A sign that mutation occurred in a person exposed to radiation in the aftermath of the Chernobyl disaster of 1986 was

A mutation that changes the codon GAA to UAA is a _____ mutation.

The type of DNA repair that corrects errors due to oxidative damage by replacing one to five nucleotides is

Which type of mutation substitutes one amino acid for another?

Homozygotes for hemoglobin C have 3-26-2013

Acridine dyes are mutagens that

A mutation is more likely to affect a differentiated cell than a stem cell due to

Ultraviolet light damages DNA by causing