Exam 12: Drugs, Microbes, Host--The Elements of Chemotherapy

The development of successful antiviral drugs has been relatively easy because viral structure is so different from the structure of eukaryotic cells.

Which is the best guide for selecting an effective antibiotic?

Drugs that are hepatotoxic cause damage to a patient's kidneys.

All of the following pertain to cephalosporins except

Drug susceptibility testing

The drug used against intestinal anaerobic bacteria, that can also alter normal flora causing antibiotic-associated colitis is

Antibiotics are derived from all the following except

Which of these drugs is used to treat cases of tuberculosis?

Species of Bacillus produce bacitracin and the polymyxins.

The macrolide, __________, is a useful substitute for dealing with penicillin-resistant Streptococci.

Which antimicrobic does not interfere with protein synthesis?

There are fewer antifungal, antiprotozoan, and antihelminth drugs compared to antibacterial drugs because these organisms

Janice has just had hip replacement surgery and her physician has prescribed antibiotics and directed her to take them every time she has a dental appointment.This is an example of antibiotic

All of the following could be reasons why antimicrobic treatment fails except

The drug used for several protozoan infections is

Resistance factor plasmids are transferred to other bacterial cells during transformation, transduction, and conjugation.

Acyclovir is used to treat

All of the following pertain to fluoroquinolones except

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Discuss the problems with development of antifungal, antiprotozoan, antihelminth, and antiviral drugs compared to the antibacterial drugs.Discuss at least 3 different modes of action that have been developed for these drugs.