Exam 14: Introduction to Metabolism

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Compound "K" is the ultimate product of a linear metabolic pathway consisting of ten enzymatically catalyzed reactions as shown below. Compound K is the ultimate product of a linear metabolic pathway consisting of ten enzymatically catalyzed reactions as shown below.    Complete the following description. If K inhibits activity of enzyme 5, then enzyme 5 is under ___ control.If enzyme 3 becomes activated in response to activity of protein kinase A only when compound A is present, then enzyme 3 is under ___ control.If enzyme 2 is only expressed in the presence of high concentrations of A, then enzyme 2 is under ___ control.If all of these are true, high concentrations of __ will decrease the flux through the pathway. Complete the following description. If "K" inhibits activity of enzyme "5", then enzyme "5" is under ___ control.If enzyme "3" becomes activated in response to activity of protein kinase A only when compound "A" is present, then enzyme "3" is under ___ control.If enzyme "2" is only expressed in the presence of high concentrations of "A," then enzyme "2" is under ___ control.If all of these are true, high concentrations of "__" will decrease the flux through the pathway.

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Use the table below to rank the redox centers in order of increasing ability to produce a favorable electron flow. Use the table below to rank the redox centers in order of increasing ability to produce a favorable electron flow.

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Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate \rarr Acetoacetyl-CoA + Succinate Δ\Delta G°' = -1.25 kJ/mol This reaction is

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The Keq is 0.503 at 25°C for the following reaction.What is the Δ\Delta G°' for this reaction? D-Glucose-6-phosphate \rarr D-Fructose-6-phosphate Δ\Delta G°'= ?

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Cells control or regulate the flux through metabolic pathways by means of I.allosteric control of enzymes. II.covalent modification of enzymes. III.genetic control of the concentrations of enzymes. IV.genetic expression of allosteric effectors.

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If the diagram below represents a catabolic pathway, and enzyme 1 requires NAD+, what type of reaction does enzyme 1 catalyze? If the diagram below represents a catabolic pathway, and enzyme 1 requires NAD<sup>+</sup>, what type of reaction does enzyme 1 catalyze?

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The conversion of triacylglycerides into fatty acids for the purpose of energy generation is an example of which of the following?

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Which of the numbered arrows in the figure points toward a high-energy phosphoanhydride bond? Which of the numbered arrows in the figure points toward a high-energy phosphoanhydride bond?

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Which of the following is (are)true regarding vitamins? I.They are essential organic molecules an organism is unable to synthesize. II.Some water soluble vitamins mediate electron-transfer reactions. III.In humans, the water soluble vitamins converted into organic coenzymes. IV.In humans, the fat soluble vitamins mediate group transfer reactions.

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In eukaryotes, glycolysis typically occurs in the

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I have discovered a new metabolic enzyme which utilizes NAD+ as a coenzyme.Which of the following could be true based on this information?

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Acetyl-CoA contains a ____ bond which often provides the energy required for substrate-level phosphorylation.

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A researcher is interested in determining if a long term change in the carbohydrate content of an individual's diet alters the levels of expression of carbohydrate metabolizing enzymes.Which of the following would address this question?

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______ is the most reliable systems biology approach to assess gene expression.

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Matching -Prokaryotes that are able to synthesize all of their cellular components from simple molecules such as CO2, H2O, NH3, and H2S are called ______.

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Which of the following increase the phosphate transfer potential of compound? I.electrostatic repulsion between charged groups on the reactant II.resonance stabilization of the hydrolysis products III.greater energy of solvation of the hydrolysis products IV.the presence of a enol group in the reactants

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Obligate aerobes

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Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate \rarr Acetoacetyl-CoA + Succinate Δ\Delta G°' = -1.25 kJ/mol What is the Keq for this reaction at 25°C?

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Acyl phosphates such as 1,3-bisphosphoglycerate have a ______ phosphoryl group transfer potential compared to ATP, which can be recognized by the _______ Δ\Delta G°' values for hydrolysis.

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Which compound is in the highest oxidation state?

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