Exam 25: Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

The antibody present in the patient's serum in posttransfusion purpura is directed against the platelet antigen __________.

Heparin induced thrombocytopenia is caused by:

The laboratory tests used in the diagnosis of vWD include all of the following except:

The average platelet count ranges from __________ of whole blood.

Which qualitative congenital platelet disorder is characterized by a prolonged bleeding time; unusually large platelets; and decrease in platelet surface glycoprotein Ib, glycoprotein V, and glycoprotein IX resulting in decreased platelet adhesion?

Endothelial cells and __________ are known to synthesize vWF.

Decreased platelet production may be associated with congenital or acquired disorders that affect the bone marrow, resulting in __________.

A deficiency of ___________________ results in gray platelet syndrome:

Which purpose would a splenectomy serve in treatment of acute ITP?

How is May-Hegglin anomaly distinguished from Bernard-Soulier syndrome?

All of the following are clinical features of TTP except:

The prolonged bleeding time and abnormal platelet adhesion seen in vWD is due to the lack of __________.

Laboratory findings in TTP include all of the following except:

vWD is characterized by:

All of the following are established criteria for the diagnosis of Bernard-Soulier syndrome except:

What is the treatment of choice to convert the hemostatic defect in uremia?

The congenital disorders of platelet function include defects in all of the following except:

In patients with alcoholic cirrhosis, thrombocytopenia and platelet abnormalities may result from the direct toxic effect of alcohol on bone marrow __________, leading to an ineffective thrombopoiesis.

The etiology of Glanzmann's thrombasthenia results from the inability of __________ to bind to platelet surface membranes, which would normally result in aggregation.

__________ results from immunization of the mother by fetal platelet antigen and placental transfer of maternal antibody.