Question 1

What is a major adverse effect associated with the drug AZT used in the treatment of AIDS?

Accepted Answer

A)  Leukocytosis 
B)  Anemia 
C)  Cardiac failure 
D)  Thrombocytosis 
E)  Erythrocytosis 
A)  Leukocytosis 
B)  Anemia 
C)  Cardiac failure 
D)  Thrombocytosis 
E)  Erythrocytosis

Question 2

Shortened red cell survival in anemia of inflammation may be due to:

Accepted Answer

A)  Autoantibodies directed against red cell antigen 
B)  Decreased protoporphyrin synthesis 
C)  Red cell membrane defect 
D)  Extracorpuscular effects of activated macrophage-monocytes of the reticuloendothelial system (RES) 
E)  Intravascular hemolysis 
A)  Autoantibodies directed against red cell antigen 
B)  Decreased protoporphyrin synthesis 
C)  Red cell membrane defect 
D)  Extracorpuscular effects of activated macrophage-monocytes of the reticuloendothelial system (RES) 
E)  Intravascular hemolysis

Question 3

The hematologic picture seen in HIV-positive patients reveals:

Accepted Answer

A)  Reticulocytopenia 
B)  Increased bone marrow reticulin 
C)  Progressive aplasia 
D)  Normocytic hypoproliferative anemia 
E)  All of the above 
A)  Reticulocytopenia 
B)  Increased bone marrow reticulin 
C)  Progressive aplasia 
D)  Normocytic hypoproliferative anemia 
E)  All of the above

Question 4

Which of the following RBC morphologies can be seen on the peripheral smear of a patient with liver disease?

Accepted Answer

A)  Macrocytes 
B)  Acanthocytes 
C)  Target cells 
D)  All of the above 
E)  None of the above 
A)  Macrocytes 
B)  Acanthocytes 
C)  Target cells 
D)  All of the above 
E)  None of the above

Question 5

The term that best describes bone marrow infiltration by malignant tumors is:

Accepted Answer

A)  Myelofibrosis 
B)  Myelodysplasia 
C)  Myelophthisic 
D)  Myeloproliferative 
E)  Hyperproliferative 
A)  Myelofibrosis 
B)  Myelodysplasia 
C)  Myelophthisic 
D)  Myeloproliferative 
E)  Hyperproliferative

Question 6

In the anemia of alcoholism, treatment of the underlying __________ disease is essential to the reversal of anemia.

Accepted Answer

A)  Kidney 
B)  Liver 
C)  Thyroid 
D)  Renal 
E)  Lymph node 
A)  Kidney 
B)  Liver 
C)  Thyroid 
D)  Renal 
E)  Lymph node

Question 7

Iron deficiency in patients with chronic liver disease is due to:

Accepted Answer

A)  Blood loss 
B)  Poor dietary habits 
C)  Dysfunctional porphyria 
D)  Dysfunctional hemoglobin 
E)  None of the above 
A)  Blood loss 
B)  Poor dietary habits 
C)  Dysfunctional porphyria 
D)  Dysfunctional hemoglobin 
E)  None of the above

Question 8

Most HIV-infected patients develop __________.

Accepted Answer

A)  Reticulocytosis 
B)  Leukocytosis 
C)  Pancytopenia 
D)  Macrocytosis 
E)  Erythrocytosis 
A)  Reticulocytosis 
B)  Leukocytosis 
C)  Pancytopenia 
D)  Macrocytosis 
E)  Erythrocytosis

Question 9

Hemolytic anemia seen in alcoholics occurs as a result of hemolysis in the __________.

Accepted Answer

A)  Kidney 
B)  Liver 
C)  Pancreas 
D)  Spleen 
E)  Lungs 
A)  Kidney 
B)  Liver 
C)  Pancreas 
D)  Spleen 
E)  Lungs

Question 10

Electrolyte disturbances in patients with renal failure can lead to the formation of these cells on the peripheral blood smear:

Accepted Answer

A)  Burr cells 
B)  Nucleated red blood cells 
C)  Macrocytes 
D)  Target cells 
E)  Spherocytes 
A)  Burr cells 
B)  Nucleated red blood cells 
C)  Macrocytes 
D)  Target cells 
E)  Spherocytes

Question 11

Folate deficiency in patients with liver disease is usually due to:

Accepted Answer

A)  Blood loss 
B)  Poor dietary habits 
C)  Antibodies to intrinsic factor 
D)  Dysfunctional hemoglobin 
E)  Dysfunctional iron metabolism 
A)  Blood loss 
B)  Poor dietary habits 
C)  Antibodies to intrinsic factor 
D)  Dysfunctional hemoglobin 
E)  Dysfunctional iron metabolism

Question 12

In the anemia of inflammation, one of the ways the body attempts to compensate for the anemia is:

Accepted Answer

A)  An increase in EPO (erythropoietin) production by kidneys 
B)  A decrease in EPO (erythropoietin) production by kidneys 
C)  An increase in iron stores 
D)  An increase in hemoglobin synthesis 
E)  An increase in transferrin synthesis 
A)  An increase in EPO (erythropoietin) production by kidneys 
B)  A decrease in EPO (erythropoietin) production by kidneys 
C)  An increase in iron stores 
D)  An increase in hemoglobin synthesis 
E)  An increase in transferrin synthesis

Exam 14: Hypoproliferative Anemia: Anemia Associated With Systemic Diseases

What is a major adverse effect associated with the drug AZT used in the treatment of AIDS?

Shortened red cell survival in anemia of inflammation may be due to:

The hematologic picture seen in HIV-positive patients reveals:

Which of the following RBC morphologies can be seen on the peripheral smear of a patient with liver disease?

The term that best describes bone marrow infiltration by malignant tumors is:

In the anemia of alcoholism, treatment of the underlying __________ disease is essential to the reversal of anemia.

Iron deficiency in patients with chronic liver disease is due to:

Most HIV-infected patients develop __________.

Hemolytic anemia seen in alcoholics occurs as a result of hemolysis in the __________.

Electrolyte disturbances in patients with renal failure can lead to the formation of these cells on the peripheral blood smear:

Folate deficiency in patients with liver disease is usually due to:

In the anemia of inflammation, one of the ways the body attempts to compensate for the anemia is:

Morphology of Human Blood and Marrow Cells: Hematopoiesis

Bone Marrow

The Red Blood Cell: Structure and Function

Anemia: Diagnosis and Clinical Considerations

Evaluation of Red Blood Cell Morphology and Introduction to Platelet and White Blood Cell Morphology

Iron Metabolism and Hypochromic Anemias

Megaloblastic Anemias

Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Introduction to Hemolytic Anemias: Intracorpuscular Defects: I Hereditary Defects of the Red Cell Membrane

Hemolytic Anemias: Intracorpuscular Defects: II Hereditary Enzyme Deficiencies

Hemolytic Anemias: Intracorpuscular Defects: III the Hemoglobinopathies

Hemolytic Anemias: Intracorpuscular Defects: Iv Thalassemia

Hemolytic Anemias: Extracorpuscular Defects

Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis

Introduction to Leukemia and the Acute Leukemias

Chronic Myeloproliferative Disorders I: Chronic Myelogenous Leukemia

Chronic Myeloproliferative Disorders Ii: Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis

Myelodysplastic Syndromes

Chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders

The Lymphomas

Multiple Myeloma and Related Plasma Cell Disorders

Lipid Lysosomal Storage Diseases and Histiocytosis

Introduction to Hemostasis

Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders

Disorders of Plasma Clotting Factors

Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

Introduction to Thrombosis and Anticoagulant Therapy

Quality Control in the Hematology Laboratory

Body Fluid Examination: the Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids

Hematology Methods

Principles of Automated Differential Analysis

Coagulation Procedures

Applications of Flow Cytometry to Hematology and Hemostasis

Molecular Diagnostic Techniques in Hematopathology

Special Stainscytochemistry

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