Question 1

The Claisen condensation produces which of these?

Accepted Answer

A)  An $\infty$-keto ester 
B)  A $\beta$-keto ester 
C)  A $\beta$-hydroxy ester 
D)  A $\beta$-hydroxyaldehyde 
E)  A $\beta$-diketone 
A)  An $\infty$-keto ester 
B)  A $\beta$-keto ester 
C)  A $\beta$-hydroxy ester 
D)  A $\beta$-hydroxyaldehyde 
E)  A $\beta$-diketone

Question 2

What product(s)result from the Claisen condensation carried out with an equimolar mixture of ethyl acetate and ethyl propanoate?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  All of these 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  All of these

Question 3

Suggest a reasonable mechanism for the following reaction.

Accepted Answer

The answer of Suggest a reasonable mechanism for the following...

Question 4

What starting compound(s)would you use in an aldol reaction to prepare as the major product:

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 5

-Consider the synthesis above in answering this question.What is compound A?

Accepted Answer

A)  Butanone 
B)  Butanal 
C)  Propanal 
D)  1-Butanol 
E)  2-Methylpropanal 
A)  Butanone 
B)  Butanal 
C)  Propanal 
D)  1-Butanol 
E)  2-Methylpropanal

Question 6

Which compound could be prepared using a Michael reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 7

Suggest a reasonable synthetic strategy to carry out the following transformation.

Accepted Answer

The answer of Suggest a reasonable synthetic strategy to carry...

Question 8

If butanal is added slowly to an aqueous solution of sodium hydroxide and 2,2-dimethylpropanal at 25 $\degree$C,the principal product is which of these?

Accepted Answer

A) 
  
B) 
  
C) 
  
D) 
  
E) 
  
A) 
  
B) 
  
C) 
  
D) 
  
E)

Question 9

What starting compound(s)would you use in an aldol reaction to prepare

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 10

What is the product of the Dieckmann condensation of this diester,

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  I and II 
E)  I,II,and III 
A)  I 
B)  II 
C)  III 
D)  I and II 
E)  I,II,and III

Question 11

What is the final product of the following reaction sequence? Give structural details of all significant intermediates.

Accepted Answer

The answer of What is the final product of the...

Question 12

The reaction of diethyl hexanedioate with sodium ethoxide would give as the product:

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 13

The aldol condensation product formed from 3-pentanone in the presence of base has the IUPAC name:

Accepted Answer

A)  5-Ethyl-4-methyl-4-hepten-3-one 
B)  5-Ethyl-4-methyl-5-hepten-3-one 
C)  4-Methyl-4-nonen-3,7-dione 
D)  3-Ethyl-4-methyl-3-hepten-5-one 
E)  3-Ethyl-4-methyl-2-hepten-5-one 
A)  5-Ethyl-4-methyl-4-hepten-3-one 
B)  5-Ethyl-4-methyl-5-hepten-3-one 
C)  4-Methyl-4-nonen-3,7-dione 
D)  3-Ethyl-4-methyl-3-hepten-5-one 
E)  3-Ethyl-4-methyl-2-hepten-5-one

Question 14

What is the final product of the following reaction sequence? Give structural
details of all significant intermediates.

Accepted Answer

The answer of What is the final product of the...

Question 15

What would be the major product of the following reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 16

Which of these compounds can react with 4-methylpentanal to afford good yields of the crossed aldol product?

Accepted Answer

A)  3-(4-Nitrophenyl)propanal 
B)  2-Ethyl-2-methylheptanal 
C)  2-(4-Nitrophenyl)propanal 
D)  3-(4-Nitrophenyl)-2-butanone 
E)  None of the above compounds will give good yields of the crossed aldol product with 4-methylhexanal. 
A)  3-(4-Nitrophenyl)propanal 
B)  2-Ethyl-2-methylheptanal 
C)  2-(4-Nitrophenyl)propanal 
D)  3-(4-Nitrophenyl)-2-butanone 
E)  None of the above compounds will give good yields of the crossed aldol product with 4-methylhexanal.

Question 17

What would be the final product of the following reaction sequence?

Accepted Answer

A)  C6H5CH2CH2CH2CH3 
B) 
  
C) 
  
D) 
  
E) 
  
A)  C6H5CH2CH2CH2CH3 
B) 
  
C) 
  
D) 
  
E)

Question 18

Which reagents would be used in a Mannich reaction to synthesize

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 19

What is the expected product from the following reaction sequence?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 20

In the aldol cyclization reaction of the following compound,predict the major product formed and explain your choice.

Accepted Answer

Of the two possible products f

Exam 19: Synthesis and Reactions of Beta-Dicarbonyl Compounds: More Chemistry of Enolate Ions

The Claisen condensation produces which of these?

What product(s)result from the Claisen condensation carried out with an equimolar mixture of ethyl acetate and ethyl propanoate?

Suggest a reasonable mechanism for the following reaction.

What starting compound(s)would you use in an aldol reaction to prepare as the major product:

-Consider the synthesis above in answering this question.What is compound A?

Which compound could be prepared using a Michael reaction?

Suggest a reasonable synthetic strategy to carry out the following transformation.

If butanal is added slowly to an aqueous solution of sodium hydroxide and 2,2-dimethylpropanal at 25 °\degree° C,the principal product is which of these?

What starting compound(s)would you use in an aldol reaction to prepare

What is the product of the Dieckmann condensation of this diester,

What is the final product of the following reaction sequence? Give structural details of all significant intermediates.

The reaction of diethyl hexanedioate with sodium ethoxide would give as the product:

The aldol condensation product formed from 3-pentanone in the presence of base has the IUPAC name:

What is the final product of the following reaction sequence? Give structural details of all significant intermediates.

What would be the major product of the following reaction?

Which of these compounds can react with 4-methylpentanal to afford good yields of the crossed aldol product?

What would be the final product of the following reaction sequence?

Which reagents would be used in a Mannich reaction to synthesize

What is the expected product from the following reaction sequence?

In the aldol cyclization reaction of the following compound,predict the major product formed and explain your choice.

Carbon Compounds and Chemical Bonds

Representative Carbon Compounds: Functional Groups, Intermolecular Forces, and Infrared Ir Spectroscopy

An Introduction to Organic Reactions: Acids and Bases

Alkanes: Nomenclature, Conformational Analysis, and an Introduction to Synthesis

Stereochemistry: Chiral Molecules

Ionic Reactions - Nucleophilic Substitution and Elimination Reactions of Alkyl Halides

Alkenes and Alkynes I: Properties and Synthesis, Elimination Reactions of Alkyl Halides

Alkenes and Alkynes Ii: Addition Reactions

Nuclear Magnetic Resonance and Mass Spectrometry: Tools for Structure Determination

Radical Reactions

Alcohols and Ethers

Alcohols From Carbonyl Compounds Oxidation-Reduction and Organometallic Compounds

Conjugated Unsaturated Systems

Aromatic Compounds

Reactions of Aromatic Compounds

Aldehydes and Ketones I Nucleophilic Addition to the Carbonyl Group

Aldehydes and Ketones Ii Aldol Reactions

Carboxylic Acids and Their Derivatives Nucleophilic Addition - Elimination at the Acyl Carbon

Amines

Phenols and Aryl Halides: Nucleophilic Aromatic Substitution

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids and Protein Synthesis

Filters

If butanal is added slowly to an aqueous solution of sodium hydroxide and 2,2-dimethylpropanal at 25 $\degree$ C,the principal product is which of these?