Exam 10: Enzymes: Classification, Kinetics, and Control

An inhibitor that must be metabolized by the enzyme before it becomes covalently attached to the enzyme is called a mechanism-based inhibitor. What is another term that has been used for such an inhibitor?

The movement of a tyrosyl residue in carboxypeptidase A when its substrate binds is an example of

Which of the following is NOT an assumption in the Michaelis Menten model for enzyme kinetic behavior?

Enzymes which are in an inactive form after the removal of a cofactor or prosthetic group are termed:

In a reaction catalyzed by a dehydrogenase, it was observed that NAD⁺ was required for binding of the second substrate. The reduced form of NAD was found to be a competitive inhibitor against NAD⁺. Which of the mechanisms listed below describes the action of this enzyme?

The degree of inhibition caused by a competitive inhibitor can be decreased by

When a reaction reaches equilibrium,

Activation of zymogens is often accomplished by

All reactions are technically reversible. Why are some considered de facto irreversible?

A competitive inhibitor

Serum isoenzyme measurements are useful in diagnosis because

For an enzyme reaction that requires a coenzyme

A Ramachandran plot is useful in

All of the following effects may occur in enzyme catalysis EXCEPT which one?

The fact that an enzyme-catalyzed reaction is first order with respect to substrate at low substrate concentration but becomes zero order with respect to substrate at high substrate concentration is explained by

Each of the following statements about the Michaelis-Menten equation is correct EXCEPT which one?

The turnover number of an enzyme catalyzed reaction is:

The enzyme hexokinase, which can utilize ATP and glucose to form glucose-6-phosphate and ADP, would be classified as a(an):

In the spectrophotometric assay for lactate dehydrogenase (LDH) activity which of the following reaction components is monitored at a wavelength of nanometers?

Select the statement which most correctly describes biotin.