Exam 13: Passing on Lifes Information: Dna Structure and Replication

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Watson and Crick's experiments involved isolating DNA, generating X-ray diffraction images of the DNA, and building a model of its structure.

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A key part of DNA's function is to encode information. In considering how information-rich a particular molecule might be, a question is how many different sequences are possible in a particular length of the molecule. In the case of DNA the four different nucleotides can be arranged in any order. How many different sequences are possible for a DNA strand three nucleotides long?

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The two strands of a double helix of DNA are linked by what kind of bond?

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What is the cause of Huntington disease?

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A trinucleotide repeat refers to:

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The structure of DNA allows the molecule to replicate itself.

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The building blocks of DNA are:

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The average mutation rate for DNA replication is 1 mutation for every 10 billion (10,000,000,000) nucleotides of DNA replicated. Yet DNA polymerase makes a mistake during replication at an average of 1 in 100,000 nucleotides. What does this say about DNA replication?

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Imagine that the DNA replication error rate for a strain of bacterium that has a defective repair mechanism is 1 in 10 million. If the cell's genome is 5 million nucleotide pairs, how often will the genome sustain a mutation in this strain, keeping in mind that both strands of a DNA molecule are replicated at once?

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What is the relationship between mutations and cancer?

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What is the function of DNA polymerase?

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Watson and Crick discovered:

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The structure of DNA allows the molecule to store information.

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Which type of mutation will have the most impact from an evolutionary point of view?

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Refer to the figure below, and then answer the question that follows. Refer to the figure below, and then answer the question that follows.   -A mistake is made during DNA replication, so there is incorrect base pairing in the DNA. Depending on how the replication repair mechanism fixes this problem, a point mutation may or may not result. What might the replication repair mechanism do, and would it result in a point mutation? -A mistake is made during DNA replication, so there is incorrect base pairing in the DNA. Depending on how the replication repair mechanism fixes this problem, a point mutation may or may not result. What might the replication repair mechanism do, and would it result in a point mutation?

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What is the relationship between DNA and proteins?

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What is one way that incorrect nucleotides are removed from a newly synthesized molecule of DNA?

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Which of the following is not a component of DNA nucleotides?

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Errors never occur in DNA replication because the DNA polymerases edit out mistakes.

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How is the information that specifies a protein stored in DNA?

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