Exam 4: Protein Structure

Protein secondary structures such as $\alpha$ -helices and $\beta$ -sheets are stabilized mainly by

Draw the reaction by which a protein disulfide bond forms.

Which statement about amino acids is true?

The amino acid with the most hydrophobic side chain is

All of the following are types of protein secondary structure EXCEPT

Describe generally how a gain-of-function protein folding disease can lead to cell death.

Shown is the titration curve for the amino acid aspartic acid. Draw the predominant protonation state of aspartic acid found at point A in the curve.

Would a nonsense mutation in a gene encoding a protein be expected to result in a gain-of-function or a loss-of-function protein folding disease?

How many possible unique triplet codons could there be in a genome?

Which represents the correct arrangement of bonding in a peptide bond?

List the levels of protein structure and give a brief description of each.

Which of the following statements about the chamber-type chaperone protein GroEL-GroES is correct?

The dipole moment associated with a peptide bond proceeds from which amide?

The protein fold known as the Rossman fold is found in proteins that commonly bind

Which statement about the $\alpha$ -helix is true?

Which amino acid side chain from the list below is the most polar?

Which gives rise to a favorable enthalpic ( $\Delta$ S) driving force for protein folding?

What is the approximate net charge of the molecule shown below at pH 7?

Cells deal with misfolded proteins by

How many possible protein primary structures are there for a tripeptide given the 20 amino acids?