Question 1

An example of experimental biochemistry is trying an experiment and

Accepted Answer

A)  quitting after it fails to prove your hypothesis. 
B)  continuing to try with no changes to protocol. 
C)  optimizing experimental design. 
D)  successfully proving your hypothesis after the first attempt. 
A)  quitting after it fails to prove your hypothesis. 
B)  continuing to try with no changes to protocol. 
C)  optimizing experimental design. 
D)  successfully proving your hypothesis after the first attempt. C

Question 2

Even though amylose and cellulose contain the same repeating unit of glucose, they are very different in terms of function. Why?

Accepted Answer

A)  A glycosidic bond cannot be cleaved. 
B)  The orientations of the glycosidic bond are different. 
C)  ATP cannot be generated from amylose. 
D)  There is no structural difference between the polymers. 
A)  A glycosidic bond cannot be cleaved. 
B)  The orientations of the glycosidic bond are different. 
C)  ATP cannot be generated from amylose. 
D)  There is no structural difference between the polymers. B

Question 3

Proteins are a polymer of __________, whereas nucleic acids are polymers of _.

Accepted Answer

A)  nucleotides; fatty acid esters 
B)  nucleotides; amino acids 
C)  amino acids; nucleotides 
D)  sugars; nucleotides 
A)  nucleotides; fatty acid esters 
B)  nucleotides; amino acids 
C)  amino acids; nucleotides 
D)  sugars; nucleotides C

Question 4

Which of the following is an example of an ecosystem?

Accepted Answer

A)  mammals 
B)  plasma membrane 
C)  insects 
D)  forest 
A)  mammals 
B)  plasma membrane 
C)  insects 
D)  forest

Question 5

The DNA double helix is stabilized by the interactions between nucleotides because of __________ between nucleotides.

Accepted Answer

A)  hydrogen bonding 
B)  pi-pi stacking 
C)  sigma bonds 
D)  ionic interactions 
A)  hydrogen bonding 
B)  pi-pi stacking 
C)  sigma bonds 
D)  ionic interactions

Question 6

Describe how a receptor is activated and inactivated by a ligand in the figure below.

Accepted Answer

The receptor ligand is bound t

Question 7

A requirement for a covalent bond to form between two atoms is that

Accepted Answer

A)  there are unpaired electrons on each atom. 
B)  the atoms are ions. 
C)  both the atoms must be metals. 
D)  one of the atoms must be a halogen. 
A)  there are unpaired electrons on each atom. 
B)  the atoms are ions. 
C)  both the atoms must be metals. 
D)  one of the atoms must be a halogen.

Question 8

When a ligand binds to a receptor, it causes the receptor to

Accepted Answer

A)  degrade. 
B)  activate. 
C)  deactivate. 
D)  rapidly grow. 
A)  degrade. 
B)  activate. 
C)  deactivate. 
D)  rapidly grow.

Question 9

Enzymes and chromosome are found where in the bacterial cell?

Accepted Answer

A)  nucleoid 
B)  pili 
C)  cytoplasm 
D)  capsule 
A)  nucleoid 
B)  pili 
C)  cytoplasm 
D)  capsule

Question 10

Evaluate the following statement: Two amino acid sequences with high sequence conservation must have the same function in an organism.

Accepted Answer

Although two amino acid sequences with h

Question 11

What process replicates DNA to make more DNA?

Accepted Answer

A)  DNA transcription 
B)  DNA replication 
C)  DNA translation 
D)  RNA transcription 
A)  DNA transcription 
B)  DNA replication 
C)  DNA translation 
D)  RNA transcription

Question 12

The proposal that DNA is a double helix was based on what experimental evidence?

Accepted Answer

A)  NMR 
B)  IR 
C)  HPLC 
D)  x-ray crystallography 
A)  NMR 
B)  IR 
C)  HPLC 
D)  x-ray crystallography

Question 13

The figure below shows an example of which functional group?

Accepted Answer

A)  amino 
B)  hydroxyl 
C)  phosphoryl 
D)  methyl 
A)  amino 
B)  hydroxyl 
C)  phosphoryl 
D)  methyl

Question 14

Triacylglycerols are neutral molecules made of

Accepted Answer

A)  three fatty acid esters covalently linked to glycine. 
B)  three fatty acid esters covalently linked to glycerol. 
C)  two fatty acid esters covalently linked to glycine. 
D)  three acyls covalently linked to glycerol. 
A)  three fatty acid esters covalently linked to glycine. 
B)  three fatty acid esters covalently linked to glycerol. 
C)  two fatty acid esters covalently linked to glycine. 
D)  three acyls covalently linked to glycerol.

Question 15

Differentiate between germ-line cell mutations and somatic cell mutations.

Accepted Answer

Although both are mutations in DNA, if t

Question 16

Humans do not have the enzyme cellulase. Is it likely that a human could survive on a plant-only diet?

Accepted Answer

A)  No, not enough ATP would be produced to generate energy. 
B)  No, not enough DNA would be produced to generate energy. 
C)  Yes, cellulase is not necessary to break down plant material. 
D)  Yes, ATP is not necessary to maintain life. 
A)  No, not enough ATP would be produced to generate energy. 
B)  No, not enough DNA would be produced to generate energy. 
C)  Yes, cellulase is not necessary to break down plant material. 
D)  Yes, ATP is not necessary to maintain life.

Question 17

Why are fewer polypeptide sequences encountered biologically than are theoretically possible?

Accepted Answer

A)  There is no way to make all the theoretical possibilities. 
B)  The phosphodiester linkages don't allow for all the possibilities. 
C)  Not all have useful structural and functional properties. 
D)  Not all of the possibilities can be broken down. 
A)  There is no way to make all the theoretical possibilities. 
B)  The phosphodiester linkages don't allow for all the possibilities. 
C)  Not all have useful structural and functional properties. 
D)  Not all of the possibilities can be broken down.

Question 18

The amino acid sequence of a protein determines its structure. Which of the following statements is true?

Accepted Answer

A)  Two proteins with similar amino acid sequence should have similar structures. 
B)  Two proteins with different amino acid sequences will have identical structures. 
C)  Two proteins with similar amino acid sequences will always have the same function in a cell. 
D)  It is impossible to determine how proteins will fold based on the amino acid sequence alone. 
A)  Two proteins with similar amino acid sequence should have similar structures. 
B)  Two proteins with different amino acid sequences will have identical structures. 
C)  Two proteins with similar amino acid sequences will always have the same function in a cell. 
D)  It is impossible to determine how proteins will fold based on the amino acid sequence alone.

Question 19

Vitamin B2 is a metabolite. Lack of vitamin B2 can lead to blurred vision and a swollen tongue. Vitamin B2 has such a strong effect on health because metabolites

Accepted Answer

A)  are the catalysts that drive biochemical reactions necessary for life-sustaining processes. 
B)  are complex chemical reactions in cells. 
C)  process essential genetic information needed for life. 
D)  are needed for construction of microtubules. 
A)  are the catalysts that drive biochemical reactions necessary for life-sustaining processes. 
B)  are complex chemical reactions in cells. 
C)  process essential genetic information needed for life. 
D)  are needed for construction of microtubules.

Question 20

Given a DNA sequence of 3 ' -CAT-5 ' , what is the complementary sequence in mRNA?

Accepted Answer

A)  5 ' -GUA-3 ' 
B)  5 ' -AUG-3 ' 
C)  3 ' -GUA-5 ' 
D)  5 ' -GTA-3 ' 
A)  5 ' -GUA-3 ' 
B)  5 ' -AUG-3 ' 
C)  3 ' -GUA-5 ' 
D)  5 ' -GTA-3 '

Exam 1: Principles of Biochemistry

An example of experimental biochemistry is trying an experiment and

Even though amylose and cellulose contain the same repeating unit of glucose, they are very different in terms of function. Why?

Proteins are a polymer of __________, whereas nucleic acids are polymers of _.

Which of the following is an example of an ecosystem?

The DNA double helix is stabilized by the interactions between nucleotides because of __________ between nucleotides.

Describe how a receptor is activated and inactivated by a ligand in the figure below.

A requirement for a covalent bond to form between two atoms is that

When a ligand binds to a receptor, it causes the receptor to

Enzymes and chromosome are found where in the bacterial cell?

Evaluate the following statement: Two amino acid sequences with high sequence conservation must have the same function in an organism.

What process replicates DNA to make more DNA?

The proposal that DNA is a double helix was based on what experimental evidence?

The figure below shows an example of which functional group?

Triacylglycerols are neutral molecules made of

Differentiate between germ-line cell mutations and somatic cell mutations.

Humans do not have the enzyme cellulase. Is it likely that a human could survive on a plant-only diet?

Why are fewer polypeptide sequences encountered biologically than are theoretically possible?

The amino acid sequence of a protein determines its structure. Which of the following statements is true?

Vitamin B2 is a metabolite. Lack of vitamin B2 can lead to blurred vision and a swollen tongue. Vitamin B2 has such a strong effect on health because metabolites

Given a DNA sequence of 3 ' -CAT-5 ' , what is the complementary sequence in mRNA?

Physical Biochemistry: Energy Conversion, Water, and Membranes

Nucleic Acid Structure and Function

Protein Structure

Methods in Protein Biochemistry

Protein Function

Enzyme Mechanisms

Cell Signaling Systems

Glycolysis: a Paradigm of Metabolic Regulation

The Citrate Cycle

Oxidative Phosphorylation

Photosynthesis

Carbohydrate Structure and Function

Carbohydrate Metabolism

Lipid Structure and Function

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Metabolic Integration

DNA Replication, Repair, and Recombination

RNA Synthesis, Processing, and Gene Silencing

Protein Synthesis, Posttranslational Modification, and Transport

Gene Regulation

Filters

Vitamin B₂ is a metabolite. Lack of vitamin B₂ can lead to blurred vision and a swollen tongue. Vitamin B₂ has such a strong effect on health because metabolites

Given a DNA sequence of 3 ^' -CAT-5 ^' , what is the complementary sequence in mRNA?