Question 1

Which of the following statements about tumor suppressor genes is FALSE?

Accepted Answer

A) Gene amplification of a tumor suppressor gene is less dangerous than gene amplification of a proto-oncogene. 
B) Cells with one functional copy of a tumor suppressor gene will usually proliferate faster than normal cells. 
C) Inactivation of tumor suppressor genes leads to enhanced cell survival and proliferation. 
D) Individuals with only one functional copy of a tumor suppressor gene are more prone to cancer than individuals with two functional copies of a tumor suppressor gene. 
A) Gene amplification of a tumor suppressor gene is less dangerous than gene amplification of a proto-oncogene. 
B) Cells with one functional copy of a tumor suppressor gene will usually proliferate faster than normal cells. 
C) Inactivation of tumor suppressor genes leads to enhanced cell survival and proliferation. 
D) Individuals with only one functional copy of a tumor suppressor gene are more prone to cancer than individuals with two functional copies of a tumor suppressor gene. B

Question 2

A basal lamina

Accepted Answer

A) is a thin layer of connective-tissue cells and matrix underlying an epithelium. 
B) is a thin layer of extracellular matrix underlying an epithelium. 
C) is attached to the apical surface of an epithelium. 
D) separates epithelial cells from each other. 
A) is a thin layer of connective-tissue cells and matrix underlying an epithelium. 
B) is a thin layer of extracellular matrix underlying an epithelium. 
C) is attached to the apical surface of an epithelium. 
D) separates epithelial cells from each other. B

Question 3

Cadherins

Accepted Answer

A) are used to transfer proteins from one cell to another. 
B) mediate cell-cell attachments through homophilic interactions. 
C) are abundant in the plant cell wall. 
D) bind to collagen fibrils. 
A) are used to transfer proteins from one cell to another. 
B) mediate cell-cell attachments through homophilic interactions. 
C) are abundant in the plant cell wall. 
D) bind to collagen fibrils. B

Question 4

Drugs that block the function of oncogenic proteins hold great promise in the fight against cancer.Should cancer researchers also be attempting to design drugs that will interfere with the products of tumor suppressor genes? Explain.

Accepted Answer

Oncogenic proteins lead toward cancer, b

Question 5

Which of the following statements about cancer is FALSE?

Accepted Answer

A) Viruses cause some cancers. 
B) Tobacco use is responsible for more than 20% of all cancer deaths. 
C) A mutation in even a single cancer-critical gene is sufficient to convert a normal cell into a cancer cell. 
D) Chemical carcinogens cause cancer by changing the nucleotide sequence of DNA. 
A) Viruses cause some cancers. 
B) Tobacco use is responsible for more than 20% of all cancer deaths. 
C) A mutation in even a single cancer-critical gene is sufficient to convert a normal cell into a cancer cell. 
D) Chemical carcinogens cause cancer by changing the nucleotide sequence of DNA.

Question 6

Rb is a tumor suppressor gene; its normal function is to help restrain cell division.Loss of both copies of Rb is a causative factor in some kinds of cancer.You propose to treat these cancers by injecting the patients with a viral vector that carries a copy of the Rb gene and has the ability to infect all the cells of the body, thereby artificially driving expression of Rb in all the cells, including the cancer cells.But your colleague replies, "No! You'll kill the patient, because you will halt cell division throughout the body."
A.Why would halting cell division throughout the body kill a full-grown adult?
B.Is your colleague right in thinking that forced expression of Rb in every cell will halt all cell division?

Accepted Answer

A.Many vital tissues in the adult body,

Question 7

A certain mutation in the receptor for epidermal growth factor (EGF) causes the mutated receptor protein to send a positive signal along the associated intracellular signaling pathway even when the EGF ligand is not bound to it.This signal leads to abnormal cell proliferation in the absence of growth factor.On the basis of this information, would you class the gene for the EGF receptor as a tumor suppressor gene or a potential oncogene? Explain your answer.

Accepted Answer

The mutation described leads toward canc

Question 8

Match each protein with the correct label in Figure 20-1.   Figure 20-1
-fibronectin

Accepted Answer

The answer of Match each protein with the correct label...

Question 9

Plasmodesmata

Accepted Answer

A) permit small molecules to pass from one cell to another. 
B) are found only in animal cells. 
C) are closed by the neurotransmitter dopamine. 
D) provide tensile strength. 
A) permit small molecules to pass from one cell to another. 
B) are found only in animal cells. 
C) are closed by the neurotransmitter dopamine. 
D) provide tensile strength.

Question 10

A major distinction between the connective tissues in an animal and other main tissue types such as epithelium, nervous tissue, or muscle is the

Accepted Answer

A) ability of connective-tissue cells such as fibroblasts to change shape. 
B) amount of extracellular matrix in connective tissues. 
C) ability of connective tissues to withstand mechanical stresses. 
D) numerous connections that connective-tissue cells make with each other. 
A) ability of connective-tissue cells such as fibroblasts to change shape. 
B) amount of extracellular matrix in connective tissues. 
C) ability of connective tissues to withstand mechanical stresses. 
D) numerous connections that connective-tissue cells make with each other.

Question 11

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A)

(B)

(C)

(D)
 
 Figure 20-2
-columnar __________

Accepted Answer

The answer of Match each name below with the best...

Question 12

Mouse embryonic stem (ES) cells

Accepted Answer

A) can only be grown in the laboratory. 
B) can give rise to all tissues and cell types in the body except germ cells. 
C) can be made in the lab from human iPS cells. 
D) come from the inner cell mass of early embryos. 
A) can only be grown in the laboratory. 
B) can give rise to all tissues and cell types in the body except germ cells. 
C) can be made in the lab from human iPS cells. 
D) come from the inner cell mass of early embryos.

Question 13

At desmosomes, cadherin molecules are connected to

Accepted Answer

A) actin filaments. 
B) intermediate filaments. 
C) microtubules. 
D) gap junctions. 
A) actin filaments. 
B) intermediate filaments. 
C) microtubules. 
D) gap junctions.

Question 14

Fibroblasts organize the collagen of the extracellular matrix by

Accepted Answer

A) cutting and rejoining the fibrils. 
B) processing procollagen into collagen. 
C) twisting fibrils together to make ropelike fibers. 
D) pulling the collagen into sheets or cables after it has been secreted. 
A) cutting and rejoining the fibrils. 
B) processing procollagen into collagen. 
C) twisting fibrils together to make ropelike fibers. 
D) pulling the collagen into sheets or cables after it has been secreted.

Question 15

An adult hemopoietic stem cell found in the bone marrow

Accepted Answer

A) will occasionally produce epidermal cells when necessary. 
B) can produce only red blood cells. 
C) can undergo self-renewing divisions for the lifetime of a healthy animal. 
D) will express all the same transcription factors as those found in an unfertilized egg. 
A) will occasionally produce epidermal cells when necessary. 
B) can produce only red blood cells. 
C) can undergo self-renewing divisions for the lifetime of a healthy animal. 
D) will express all the same transcription factors as those found in an unfertilized egg.

Question 16

Which of the following statements about organoids is FALSE?

Accepted Answer

A) Organoids can be produced from ES and iPS cells. 
B) Organoids can only be made for organs that are made up of a single type of differentiated cell. 
C) Organoids are self-assembling. 
D) Organoids can form multilayered structures. 
A) Organoids can be produced from ES and iPS cells. 
B) Organoids can only be made for organs that are made up of a single type of differentiated cell. 
C) Organoids are self-assembling. 
D) Organoids can form multilayered structures.

Question 17

Which of the following is NOT an example of a connective tissue?

Accepted Answer

A) bone 
B) the layer of photoreceptors in the eye 
C) the jellylike interior of an eye 
D) cartilage 
A) bone 
B) the layer of photoreceptors in the eye 
C) the jellylike interior of an eye 
D) cartilage

Question 18

Which of the following molecules is NOT found in plants?

Accepted Answer

A) cellulose 
B) lignin 
C) collagen 
D) pectin 
A) cellulose 
B) lignin 
C) collagen 
D) pectin

Question 19

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A)

(B)

(C)

(D)
 
 Figure 20-2
-stratified __________

Accepted Answer

The answer of Match each name below with the best...

Question 20

A pluripotent cell

Accepted Answer

A) can only be produced in the laboratory. 
B) can give rise to all the tissues and cell types in the body. 
C) can only give rise to stem cells. 
D) is considered to be terminally differentiated. 
A) can only be produced in the laboratory. 
B) can give rise to all the tissues and cell types in the body. 
C) can only give rise to stem cells. 
D) is considered to be terminally differentiated.

Which of the following statements about tumor suppressor genes is FALSE?

A basal lamina

Cadherins

Drugs that block the function of oncogenic proteins hold great promise in the fight against cancer.Should cancer researchers also be attempting to design drugs that will interfere with the products of tumor suppressor genes? Explain.

Which of the following statements about cancer is FALSE?

Match each protein with the correct label in Figure 20-1. Figure 20-1 -fibronectin

Plasmodesmata

A major distinction between the connective tissues in an animal and other main tissue types such as epithelium, nervous tissue, or muscle is the

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A) (B) (C) (D) Figure 20-2 -columnar __________

Mouse embryonic stem (ES) cells

At desmosomes, cadherin molecules are connected to

Fibroblasts organize the collagen of the extracellular matrix by

An adult hemopoietic stem cell found in the bone marrow

Which of the following statements about organoids is FALSE?

Which of the following is NOT an example of a connective tissue?

Which of the following molecules is NOT found in plants?

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A) (B) (C) (D) Figure 20-2 -stratified __________

A pluripotent cell

Cells: The Fundamental Units of Life

Chemical Components of Cells

Energy, Catalysis, and Biosynthesis

Protein Structure and Function

DNA and Chromosomes

DNA Replication and Repair

From DNA to Protein

Control of Gene Expression

How Genes and Genomes Evolve

Analyzing the Structure and Function of Genes

Membrane Structure

Transport Across Cell Membranes

How Cells Obtain Energy From Food

Energy Generation in Mitochondria and Chloroplasts

Intracellular Compartments and Protein Transport

Cell Signaling

Cytoskeleton

The Cell-Division Cycle

Sexual Reproduction and the Power of Genetics

Filters

Exam 20: Cell Communities: Tissues, Stem Cells, and Cancer

Which of the following statements about tumor suppressor genes is FALSE?

A basal lamina

Cadherins

Drugs that block the function of oncogenic proteins hold great promise in the fight against cancer.Should cancer researchers also be attempting to design drugs that will interfere with the products of tumor suppressor genes? Explain.

Which of the following statements about cancer is FALSE?

Match each protein with the correct label in Figure 20-1. Figure 20-1 -fibronectin

Plasmodesmata

A major distinction between the connective tissues in an animal and other main tissue types such as epithelium, nervous tissue, or muscle is the

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A) (B) (C) (D) Figure 20-2 -columnar __________

Mouse embryonic stem (ES) cells

At desmosomes, cadherin molecules are connected to

Fibroblasts organize the collagen of the extracellular matrix by

An adult hemopoietic stem cell found in the bone marrow

Which of the following statements about organoids is FALSE?

Which of the following is NOT an example of a connective tissue?

Which of the following molecules is NOT found in plants?

Match each name below with the best depiction of the type of epithelial sheet shown in Figure 20-2.Each name and each picture will only be used once. (A) (B) (C) (D) Figure 20-2 -stratified __________

A pluripotent cell

Cells: The Fundamental Units of Life

Chemical Components of Cells

Energy, Catalysis, and Biosynthesis

Protein Structure and Function

DNA and Chromosomes

DNA Replication and Repair

From DNA to Protein

Control of Gene Expression

How Genes and Genomes Evolve

Analyzing the Structure and Function of Genes

Membrane Structure

Transport Across Cell Membranes

How Cells Obtain Energy From Food

Energy Generation in Mitochondria and Chloroplasts

Intracellular Compartments and Protein Transport

Cell Signaling

Cytoskeleton

The Cell-Division Cycle

Sexual Reproduction and the Power of Genetics

Filters