Question 1

What is the general position of the consensus sequence called the GC box? What is its sequence?

Accepted Answer

A)  promoter; CAAT 
B)  promoter; GGGCGG 
C)  terminator; CAAT 
D)  terminator; GGGCGG 
E)  attenuator; GGGCGG 
A)  promoter; CAAT 
B)  promoter; GGGCGG 
C)  terminator; CAAT 
D)  terminator; GGGCGG 
E)  attenuator; GGGCGG

Question 2

When transcription factors interact with DNA, is the resulting genetic control typically positive or negative?

Accepted Answer

The answer of When transcription factors interact with DNA, is...

Question 3

The human metallothionein IIA gene (hMTIIA) is transcriptionally regulated through the interplay of regulatory elements and transcription factors. What is the function of this gene, and how is it regulated by environmental circumstances?

Accepted Answer

The gene hMTIIA produces a protein that

Question 4

Alternative RNA processing generates different mRNAs, which can direct the synthesis of different polypeptides.

Accepted Answer

A) True 
 B)False

Question 5

One of the earliest steps in the RNAi pathway involves the association of siRNA or miRNA molecules with an enzyme complex composed mainly of reverse transcriptase.

Accepted Answer

A) True 
 B)False

Question 6

An upstream activator sequence (UAS) can function at variable distances and in either orientation. However, it differs from an enhancer in that it cannot function downstream of the transcription starting point.

Accepted Answer

A) True 
 B)False

Question 7

In what way is gene rearrangement related to gene regulation? Give an example.

Accepted Answer

The reshuffling of genes provides a way

Question 8

Name three consensus sequences or modular DNA sequences that exist upstream from the coding regions of some eukaryotic genes.

Accepted Answer

TATA, CAAT

Question 9

What evidence indicates that steroid hormones exert their influence at the level of DNA?

Accepted Answer

translocation of the hormone-r

Question 10

What are zinc fingers, and why are they frequently encountered in descriptions of genetic regulation in eukaryotes?

Accepted Answer

Zinc fingers consist of amino acid seque

Question 11

Channels between chromosomes in the interphase nucleus are called ________.

Accepted Answer

A)  extrachromosomal elements 
B)  localized zones 
C)  nonlocalized zones 
D)  interchromosomal compartments 
E)  subchromosomal territories 
A)  extrachromosomal elements 
B)  localized zones 
C)  nonlocalized zones 
D)  interchromosomal compartments 
E)  subchromosomal territories

Question 12

List at least three levels or types of genetic regulation in eukaryotes.

Accepted Answer

transcriptional, DNA

Question 13

In what way can 5′-azacytidine influence transcription?

Accepted Answer

Nitrogen is at the 5′ position of 5′-aza

Question 14

Regulation of RNA transport through the nuclear membrane is as common in prokaryotes as in eukaryotes.

Accepted Answer

A) True 
 B)False

Question 15

Describe the function and general nature of promoters in eukaryotes.

Accepted Answer

Promoter regions are necessary for the i

Question 16

In what ways are eukaryotic transcription factors thought to function?

Accepted Answer

They appear to influence the structural

Question 17

What are the approximate positions of consensus sequences (modular elements) at the 5′ end of eukaryotic genes?

Accepted Answer

GC box (-1

Question 18

Describe the general structure of a transcription factor.

Accepted Answer

Transcription factors are modu

Question 19

List three general pathways in which eukaryotic mRNA is typically degraded in eukaryotes.

Accepted Answer

poly-A binding prote

Question 20

The two major components of the immune system are humoral and cellular immunity. The humoral component ________.

Accepted Answer

A)  is involved in the production of antibodies 
B)  allows the T cells to produce antigens that then stimulate antibody production 
C)  plays a major role in the production of antigens 
D)  suppresses the production of T cells 
E)  is responsible for allowing horizontal gene transfer 
A)  is involved in the production of antibodies 
B)  allows the T cells to produce antigens that then stimulate antibody production 
C)  plays a major role in the production of antigens 
D)  suppresses the production of T cells 
E)  is responsible for allowing horizontal gene transfer

Exam 17: Regulation of Gene Expression in Eukaryotes

What is the general position of the consensus sequence called the GC box? What is its sequence?

When transcription factors interact with DNA, is the resulting genetic control typically positive or negative?

The human metallothionein IIA gene (hMTIIA) is transcriptionally regulated through the interplay of regulatory elements and transcription factors. What is the function of this gene, and how is it regulated by environmental circumstances?

Alternative RNA processing generates different mRNAs, which can direct the synthesis of different polypeptides.

One of the earliest steps in the RNAi pathway involves the association of siRNA or miRNA molecules with an enzyme complex composed mainly of reverse transcriptase.

An upstream activator sequence (UAS) can function at variable distances and in either orientation. However, it differs from an enhancer in that it cannot function downstream of the transcription starting point.

In what way is gene rearrangement related to gene regulation? Give an example.

Name three consensus sequences or modular DNA sequences that exist upstream from the coding regions of some eukaryotic genes.

What evidence indicates that steroid hormones exert their influence at the level of DNA?

What are zinc fingers, and why are they frequently encountered in descriptions of genetic regulation in eukaryotes?

Channels between chromosomes in the interphase nucleus are called ________.

List at least three levels or types of genetic regulation in eukaryotes.

In what way can 5′-azacytidine influence transcription?

Regulation of RNA transport through the nuclear membrane is as common in prokaryotes as in eukaryotes.

Describe the function and general nature of promoters in eukaryotes.

In what ways are eukaryotic transcription factors thought to function?

What are the approximate positions of consensus sequences (modular elements) at the 5′ end of eukaryotic genes?

Describe the general structure of a transcription factor.

List three general pathways in which eukaryotic mRNA is typically degraded in eukaryotes.

The two major components of the immune system are humoral and cellular immunity. The humoral component ________.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Genetics

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Extranuclear Inheritance

DNA Structure and Analysis

DNA Replication and Recombination

DNA Organization in Chromosomes

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation, Dna Repair, and Transposition

Regulation of Gene Expression in Prokaryotes

Developmental Genetics

Cancer and Regulation of the Cell Cycle

Recombinant Dna Technology

Genomics, Bioinformatics, and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Neurogenetics

Population and Evolutionary Genetics

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