Question 1

Restriction Fragment Length Polymorphism (RFLP) can be used for all but which of the following purposes?

Accepted Answer

A)  In paternity cases to determine the source of a DNA sample 
B)  To measure recombination rates, which can lead to a genetic map with the distance between RFLP loci measured in centimorgans 
C)  In criminal cases to determine the source of a DNA sample 
D)  To determine the Rh status of an individual 
A)  In paternity cases to determine the source of a DNA sample 
B)  To measure recombination rates, which can lead to a genetic map with the distance between RFLP loci measured in centimorgans 
C)  In criminal cases to determine the source of a DNA sample 
D)  To determine the Rh status of an individual

Question 2

are regions of DNA interspersed in the human genome formed by variable tandem repeats of short nucleotide sequences used in DNA fingerprinting.

Accepted Answer

A)  Minisatellites 
B)  Macrosatellites 
C)  Platelet satellites 
D)  Chromatids 
A)  Minisatellites 
B)  Macrosatellites 
C)  Platelet satellites 
D)  Chromatids

Question 3

Molecular RBC antigen typing is used:

Accepted Answer

A)  to confirm serological testing. 
B)  when serology is not possible. 
C)  when serology is not sensitive enough or discrepancies occur. 
D)  for all of the above. 
A)  to confirm serological testing. 
B)  when serology is not possible. 
C)  when serology is not sensitive enough or discrepancies occur. 
D)  for all of the above.

Question 4

In DNA cloning, the DNA fragment of interest carried by the is introduced into a host cell.

Accepted Answer

A)  plasmid 
B)  vector 
C)  protein 
D)  restriction endonucleases 
A)  plasmid 
B)  vector 
C)  protein 
D)  restriction endonucleases

Question 5

Risks for using retroviruses, adenoviruses, and lentiviruses as vectors in gene therapy include all of the following except:

Accepted Answer

A)  the exogenous gene may cause disease if overexpressed or expressed in certain cell types. 
B)  contaminants may be introduced during vector manufacture. 
C)  antitumor responses by overexpression of cytokines may occur. 
D)  there is a potential for recombination of gene therapy vectors with human endogenous sequences. 
A)  the exogenous gene may cause disease if overexpressed or expressed in certain cell types. 
B)  contaminants may be introduced during vector manufacture. 
C)  antitumor responses by overexpression of cytokines may occur. 
D)  there is a potential for recombination of gene therapy vectors with human endogenous sequences.

Restriction Fragment Length Polymorphism (RFLP) can be used for all but which of the following purposes?

are regions of DNA interspersed in the human genome formed by variable tandem repeats of short nucleotide sequences used in DNA fingerprinting.

Molecular RBC antigen typing is used:

In DNA cloning, the DNA fragment of interest carried by the is introduced into a host cell.

Risks for using retroviruses, adenoviruses, and lentiviruses as vectors in gene therapy include all of the following except:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

Exam 4: Concepts in Molecular Biology

Restriction Fragment Length Polymorphism (RFLP) can be used for all but which of the following purposes?

are regions of DNA interspersed in the human genome formed by variable tandem repeats of short nucleotide sequences used in DNA fingerprinting.

Molecular RBC antigen typing is used:

In DNA cloning, the DNA fragment of interest carried by the is introduced into a host cell.

Risks for using retroviruses, adenoviruses, and lentiviruses as vectors in gene therapy include all of the following except:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters