Question 1

Live polio virus can be used in a(n)

Accepted Answer

A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine. 
A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine.

Question 2

Which of the following is a pregnancy test used to find the fetal hormone HCG in a woman's urine using anti- HCG and latex spheres?

Accepted Answer

A)  Direct agglutination reaction 
B)  Passive agglutination reaction 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction 
A)  Direct agglutination reaction 
B)  Passive agglutination reaction 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction

Question 3

Patient's serum, Rickettsia, guinea pig complement, sheep red blood cells, and anti- sheep red blood cells are mixed in a tube. What happens if the patient has epidemic typhus?

Accepted Answer

A)  Hemagglutination 
B)  Hemolysis 
C)  Hemagglutination- inhibition 
D)  Bacteria fluoresce 
E)  None of the above 
A)  Hemagglutination 
B)  Hemolysis 
C)  Hemagglutination- inhibition 
D)  Bacteria fluoresce 
E)  None of the above

Question 4

Haemophilus influenzae b capsular polysaccharide with a protein is a(n)

Accepted Answer

A)  Conjugated vaccine. 
B)  Subunit vaccine. 
C)  Nucleic acid vaccine. 
D)  Inactivated whole- agent vaccine. 
E)  Toxoid vaccine. 
A)  Conjugated vaccine. 
B)  Subunit vaccine. 
C)  Nucleic acid vaccine. 
D)  Inactivated whole- agent vaccine. 
E)  Toxoid vaccine.

Question 5

An indirect version of which test using antihuman globulin may be used to detect patient's antibodies against Treponema pallidum?

Accepted Answer

A)  Agglutination reaction 
B)  Complement fixation 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction 
A)  Agglutination reaction 
B)  Complement fixation 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction

Question 6

In a direct ELISA test, what are you looking for in the patient?

Accepted Answer

A)  Antibodies 
B)  Either antigen or antibodies 
C)  Antigen 
D)  None of the above 
A)  Antibodies 
B)  Either antigen or antibodies 
C)  Antigen 
D)  None of the above

Question 7

Palivizumab is used to treat respiratory syncytial virus disease. The antiviral drug is

Accepted Answer

A)  A nucleoside analog. 
B)  A vaccine. 
C)  A monoclonal antibody. 
D)  An immunosuppressive. 
E)  A toxoid. 
A)  A nucleoside analog. 
B)  A vaccine. 
C)  A monoclonal antibody. 
D)  An immunosuppressive. 
E)  A toxoid.

Question 8

Haemophilus capsule polysaccharide plus diphtheria toxoid is a(n)

Accepted Answer

A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine. 
A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine.

Question 9

If a patient shows the presence of antibodies against diphtheria toxin, this indicates all of the following except

Accepted Answer

A)  A recent transfusion may have passively introduced the antibodies. 
B)  The patient may have had the disease and has recovered. 
C)  The patient may have the disease. 
D)  The patient was near someone who had the disease. 
E)  The patient may have been vaccinated. 
A)  A recent transfusion may have passively introduced the antibodies. 
B)  The patient may have had the disease and has recovered. 
C)  The patient may have the disease. 
D)  The patient was near someone who had the disease. 
E)  The patient may have been vaccinated.

Question 10

Situation 18.1
In an immunodiffusion test to diagnose histoplasmosis, patient's serum is placed in a well in an agar plate. In apositive test, a precipitate forms as the serum diffuses from the well and meets material diffusing from a second well
-In Situation 18.1, what is in the second well?

Accepted Answer

A)  Mycelia 
B)  Antibodies 
C)  Red blood cells 
D)  A fungal antigen 
E)  Fungal cells 
A)  Mycelia 
B)  Antibodies 
C)  Red blood cells 
D)  A fungal antigen 
E)  Fungal cells

Question 11

Which of the following uses fluorescent- labeled antibodies?

Accepted Answer

A)  Neutralization 
B)  Precipitation 
C)  Flow cytometry 
D)  Agglutination 
E)  Complement fixation 
A)  Neutralization 
B)  Precipitation 
C)  Flow cytometry 
D)  Agglutination 
E)  Complement fixation

Question 12

In an agglutination test, eight serial dilutions to determine antibody titer were set up: tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Accepted Answer

A)  1:32 
B)  1:6 
C)  32 
D)  64 
E)  6 
A)  1:32 
B)  1:6 
C)  32 
D)  64 
E)  6

Question 13

Which of the following is a test to determine the presence of soluble antigens in patient's saliva?

Accepted Answer

A)  Direct agglutination reaction 
B)  Passive agglutination reaction 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction 
A)  Direct agglutination reaction 
B)  Passive agglutination reaction 
C)  Immunofluorescence 
D)  Neutralization reaction 
E)  Precipitation reaction

Question 14

Purified protein from B. pertussis is a(n)

Accepted Answer

A)  Conjugated vaccine 
B)  Subunit vaccine 
C)  Nucleic acid vaccine 
D)  Attenuated whole- agent vaccine 
E)  Toxoid vaccine 
A)  Conjugated vaccine 
B)  Subunit vaccine 
C)  Nucleic acid vaccine 
D)  Attenuated whole- agent vaccine 
E)  Toxoid vaccine

Question 15

A test used to detect anti- Rickettsia antibodies in a patient is the

Accepted Answer

A)  Indirect fluorescent antibody test. 
B)  Direct fluorescent antibody test. 
C)  None of the above 
A)  Indirect fluorescent antibody test. 
B)  Direct fluorescent antibody test. 
C)  None of the above

Question 16

Which of the following is not normally used in a vaccine?

Accepted Answer

A)  Inactivated viruses 
B)  Antibodies 
C)  Toxoid 
D)  Live, attenuated bacteria 
E)  Parts of bacterial cells 
A)  Inactivated viruses 
B)  Antibodies 
C)  Toxoid 
D)  Live, attenuated bacteria 
E)  Parts of bacterial cells

Question 17

The circumsporozoite antigen of Plasmodium can be used for all of the following except to

Accepted Answer

A)  Decrease recurring infections. 
B)  Produce monoclonal antibodies. 
C)  Cure infected people. 
D)  Vaccinate healthy people. 
E)  All of the above. 
A)  Decrease recurring infections. 
B)  Produce monoclonal antibodies. 
C)  Cure infected people. 
D)  Vaccinate healthy people. 
E)  All of the above.

Question 18

Which of the following uses red blood cells as the indicator?

Accepted Answer

A)  Neutralization 
B)  Agglutination 
C)  Flow cytometry 
D)  Complement fixation 
E)  Precipitation 
A)  Neutralization 
B)  Agglutination 
C)  Flow cytometry 
D)  Complement fixation 
E)  Precipitation

Question 19

Which of the following tests is not correctly matched to its positive reaction?

Accepted Answer

A)  Complement fixation - no hemolysis 
B)  ELISA - enzyme- substrate reaction 
C)  Neutralization - no tissue/animal death 
D)  Hemagglutination - clumping of red blood cells 
E)  None of the above 
A)  Complement fixation - no hemolysis 
B)  ELISA - enzyme- substrate reaction 
C)  Neutralization - no tissue/animal death 
D)  Hemagglutination - clumping of red blood cells 
E)  None of the above

Question 20

Dead Bordetella pertussis can be used in a(n)

Accepted Answer

A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine. 
A)  Inactivated whole- agent vaccine. 
B)  Attenuated whole- agent vaccine. 
C)  Conjugated vaccine. 
D)  Subunit vaccine. 
E)  Toxoid vaccine.

Exam 18: Practical Applications of Immunology

Live polio virus can be used in a(n)

Which of the following is a pregnancy test used to find the fetal hormone HCG in a woman's urine using anti- HCG and latex spheres?

Patient's serum, Rickettsia, guinea pig complement, sheep red blood cells, and anti- sheep red blood cells are mixed in a tube. What happens if the patient has epidemic typhus?

Haemophilus influenzae b capsular polysaccharide with a protein is a(n)

An indirect version of which test using antihuman globulin may be used to detect patient's antibodies against Treponema pallidum?

In a direct ELISA test, what are you looking for in the patient?

Palivizumab is used to treat respiratory syncytial virus disease. The antiviral drug is

Haemophilus capsule polysaccharide plus diphtheria toxoid is a(n)

If a patient shows the presence of antibodies against diphtheria toxin, this indicates all of the following except

Situation 18.1 In an immunodiffusion test to diagnose histoplasmosis, patient's serum is placed in a well in an agar plate. In apositive test, a precipitate forms as the serum diffuses from the well and meets material diffusing from a second well -In Situation 18.1, what is in the second well?

Which of the following uses fluorescent- labeled antibodies?

In an agglutination test, eight serial dilutions to determine antibody titer were set up: tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Which of the following is a test to determine the presence of soluble antigens in patient's saliva?

Purified protein from B. pertussis is a(n)

A test used to detect anti- Rickettsia antibodies in a patient is the

Which of the following is not normally used in a vaccine?

The circumsporozoite antigen of Plasmodium can be used for all of the following except to

Which of the following uses red blood cells as the indicator?

Which of the following tests is not correctly matched to its positive reaction?

Dead Bordetella pertussis can be used in a(n)

The Microbial World and You

Chemical Principles

Observing Microorganisms Through a Microscope

Functional Anatomy of Prokaryotic and Eukaryotic Cells

Microbial Metabolism

Microbial Growth

The Control of Microbial Growth

Microbial Genetics

Biotechnology and Recombinant DNA

Classification of Microorganisms

The Prokaryotes: Domains Bacteria and Archaea

The Eukaryotes: Fungi, Algae, Protozoa, and Helminths

Viruses, Viroids, and Prions

Principles of Disease and Epidemiology

Microbial Mechanisms of Pathogenicity

Innate Immunity: Nonspecific Defenses of the Host

Adaptive Immunity: Specific Defenses of the Host

Disorders Associated With the Immune System

Antimicrobial Drugs

Microbial Diseases of the Skin and Eyes

Microbial Diseases of the Nervous System

Microbial Diseases of the Cardiovascular and Lymphatic Systems

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

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