Question 1

What is FISH used for and how does it work?

Accepted Answer

FISH stands for fluorescent in situ hybr

Question 2

Vegetative cells in the alga Chlamydomonas reinhardtii are diploid.

Accepted Answer

A) True 
 B)False

Question 3

A tetratype tetrad resulting from a two-point cross between a wild-type Neurospora cell and a double mutant call will contain ascospores with

Accepted Answer

A)  both the parental and recombinant genotypes. 
B)  one parental and one recombinant genotype. 
C)  both parental genotypes. 
D)  only the recombinant genotype. 
E)  only the dominant parental genotypes. 
A)  both the parental and recombinant genotypes. 
B)  one parental and one recombinant genotype. 
C)  both parental genotypes. 
D)  only the recombinant genotype. 
E)  only the dominant parental genotypes.

Question 4

Why do Neurospora crassa asci contain eight rather than four haploid spores?

Accepted Answer

Each of the four pro

Question 5

In tumor cells of humans with hereditary retinoblasta

Accepted Answer

A)  the gene RB is mutant at both loci. 
B)  the gene RB is mutant at one locus. 
C)  there is a duplication of the RB locus. 
D)  there is a 10 percent recombination rate. 
E)  the RB locus is missing. 
A)  the gene RB is mutant at both loci. 
B)  the gene RB is mutant at one locus. 
C)  there is a duplication of the RB locus. 
D)  there is a 10 percent recombination rate. 
E)  the RB locus is missing.

Question 6

What are the possible segregation patterns and genotype ratios of genes C and c in a linear tetrad in the case of second-division segregation?

Accepted Answer

In second-division segregation of genes,

Question 7

A diploid culture of Aspergillus with the genotype w ad+ pro paba+ y+ bi/w ad pro+ paba y bi+ undergoes haploidization in some sectors. The resulting haploid genotypes and their proportions are 50 percent w ad+ pro paba+ y+ bi, and 50 percent w ad pro+ paba y bi+. How do you explain these results?

Accepted Answer

The genes ad+ pro pa

Question 8

If a single crossover occurs during mitosis in heterozygotes, then

Accepted Answer

A)  loci distal to the crossover on the same chromosome arm may become homozygous. 
B)  recessive phenotypes can be expressed. 
C)  phenotypic changes are not observed. 
D)  only wild-type phenotypes are observed. 
E)  Both A and B 
A)  loci distal to the crossover on the same chromosome arm may become homozygous. 
B)  recessive phenotypes can be expressed. 
C)  phenotypic changes are not observed. 
D)  only wild-type phenotypes are observed. 
E)  Both A and B

Question 9

Organisms that achieve genetic recombination without undergoing the normal processes of meiosis and fertilization are said to have

Accepted Answer

A)  alternation of generations. 
B)  asexual systems. 
C)  sporadic sexual systems. 
D)  parasexual systems. 
E)  unisexual systems 
A)  alternation of generations. 
B)  asexual systems. 
C)  sporadic sexual systems. 
D)  parasexual systems. 
E)  unisexual systems

Question 10

How can mitotic crossing over be used to map gene order on heterozygous chromosomes?

Accepted Answer

Since mitotic crossover events result in

Question 11

During sexual reproduction in Neurospora crassa, fusion of the haploid nuclei of cells with different mating types results in ________ ascospores in an ascus.

Accepted Answer

A)  eight haploid 
B)  eight diploid 
C)  four diploid and four haploid 
D)  four diploid 
E)  four haploid 
A)  eight haploid 
B)  eight diploid 
C)  four diploid and four haploid 
D)  four diploid 
E)  four haploid

Question 12

When do you observe the 4:4 segregation pattern of genes in a linear tetrad?

Accepted Answer

A)  When the gene-centromere distance is greater than 7 map units 
B)  When the parent is a homozygote 
C)  When a single crossover between a gene and its centromere occurs 
D)  When no crossover between a gene and its centromere occurs 
E)  When the parent is a heterozygote 
A)  When the gene-centromere distance is greater than 7 map units 
B)  When the parent is a homozygote 
C)  When a single crossover between a gene and its centromere occurs 
D)  When no crossover between a gene and its centromere occurs 
E)  When the parent is a heterozygote

Question 13

First-division segregation means that

Accepted Answer

A)  both copies of an allelic pair are at the same pole after meiosis I. 
B)  centromeres of homologs segregate to different nuclear areas after the first meiotic division. 
C)  no crossover has occurred between a gene locus and the centromere. 
D)  Both A and B 
E)  All of the above 
A)  both copies of an allelic pair are at the same pole after meiosis I. 
B)  centromeres of homologs segregate to different nuclear areas after the first meiotic division. 
C)  no crossover has occurred between a gene locus and the centromere. 
D)  Both A and B 
E)  All of the above

Question 14

Tetrad analysis to create genetic maps is best performed with haploid organisms because

Accepted Answer

A)  only the dominant alleles are expressed. 
B)  only recessive alleles are expressed. 
C)  only haploid organisms produce spores. 
D)  the phenotype directly reflects the genotype. 
E)  haploid organisms have two copies of each gene. 
A)  only the dominant alleles are expressed. 
B)  only recessive alleles are expressed. 
C)  only haploid organisms produce spores. 
D)  the phenotype directly reflects the genotype. 
E)  haploid organisms have two copies of each gene.

Question 15

The fusion of the nuclei of a heterokaryon is called

Accepted Answer

A)  diploidization. 
B)  spore production. 
C)  recombination. 
D)  haploidization. 
E)  syngamy. 
A)  diploidization. 
B)  spore production. 
C)  recombination. 
D)  haploidization. 
E)  syngamy.

Question 16

How many different types of tetrads can result from a two-point cross between a wild-type Neurospora cell and a double-mutant cell?

Accepted Answer

Three: PD,

Question 17

Mitotic recombination occurs less frequently than meiotic recombination.

Accepted Answer

A) True 
 B)False

Question 18

The order of the four spore pairs within an ascus of an ordered tetrad reflects

Accepted Answer

A)  the orientation of the four chromatids of each tetrad at the metaphase plate of meiosis I. 
B)  whether or not mitosis takes place after meiosis. 
C)  the number of recombination events. 
D)  both A and B. 
E)  all of the above. 
A)  the orientation of the four chromatids of each tetrad at the metaphase plate of meiosis I. 
B)  whether or not mitosis takes place after meiosis. 
C)  the number of recombination events. 
D)  both A and B. 
E)  all of the above.

Question 19

Visible tetrads are produced during the reproductive cycle of

Accepted Answer

A)  Saccharomyces cerevisiae 
B)  Neurospora crassa 
C)  Chlamydomonas reinhardtii 
D)  Zea mays 
E)  all but D. 
A)  Saccharomyces cerevisiae 
B)  Neurospora crassa 
C)  Chlamydomonas reinhardtii 
D)  Zea mays 
E)  all but D.

Question 20

Mitotic recombination cannot occur in cells that are

Accepted Answer

A)  haploid. 
B)  aneuploid. 
C)  diploid. 
D)  polyploid. 
E)  all of the above. 
A)  haploid. 
B)  aneuploid. 
C)  diploid. 
D)  polyploid. 
E)  all of the above.

Exam 7: Chromosomal Basis of Inheritance

What is FISH used for and how does it work?

Vegetative cells in the alga Chlamydomonas reinhardtii are diploid.

A tetratype tetrad resulting from a two-point cross between a wild-type Neurospora cell and a double mutant call will contain ascospores with

Why do Neurospora crassa asci contain eight rather than four haploid spores?

In tumor cells of humans with hereditary retinoblasta

What are the possible segregation patterns and genotype ratios of genes C and c in a linear tetrad in the case of second-division segregation?

A diploid culture of Aspergillus with the genotype w ad+ pro paba+ y+ bi/w ad pro+ paba y bi+ undergoes haploidization in some sectors. The resulting haploid genotypes and their proportions are 50 percent w ad+ pro paba+ y+ bi, and 50 percent w ad pro+ paba y bi+. How do you explain these results?

If a single crossover occurs during mitosis in heterozygotes, then

Organisms that achieve genetic recombination without undergoing the normal processes of meiosis and fertilization are said to have

How can mitotic crossing over be used to map gene order on heterozygous chromosomes?

During sexual reproduction in Neurospora crassa, fusion of the haploid nuclei of cells with different mating types results in ________ ascospores in an ascus.

When do you observe the 4:4 segregation pattern of genes in a linear tetrad?

First-division segregation means that

Tetrad analysis to create genetic maps is best performed with haploid organisms because

The fusion of the nuclei of a heterokaryon is called

How many different types of tetrads can result from a two-point cross between a wild-type Neurospora cell and a double-mutant cell?

Mitotic recombination occurs less frequently than meiotic recombination.

The order of the four spore pairs within an ascus of an ordered tetrad reflects

Visible tetrads are produced during the reproductive cycle of

Mitotic recombination cannot occur in cells that are

Genetics of Bacteria and Bacteriophages

Variations in Chromosome Structure and Number

Advanced Gene Mapping in Eukaryotes

Gene Mapping in Eukaryotes

Quantitative Genetics

Extensions of Mendelian Genetic Principles

Molecular Evolution

Population Genetics

Non-Mendelian Inheritance

Genetics of Cancer

Genetic Analysis of Development

Regulation of Gene Expression in Eukaryotes

Mendelian Genetics

Regulation of Gene Expression in Bacteria and Bacteriophages

Genomics

Applications of Recombinant DNA Technology

Recombinant DNA Technology

DNA Mutation, DNA Repair, and Transposable Elements

Gene Expression: Translation

Gene Expression: Transcription

Gene Control of Proteins

DNA Replication

DNA: The Genetic Material

Genetics: an Introduction

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