Question 1

Which of the following repair mechanisms would most likely be used to repair a G in DNA damaged by oxidation?

Accepted Answer

A)  Base Excision: 
B)  Nucleotide Excision 
C)  Pol III Proofreading 
D)  Mismatch Repair 
A)  Base Excision: 
B)  Nucleotide Excision 
C)  Pol III Proofreading 
D)  Mismatch Repair

Question 2

Which is most likely to have a high processivity?

Accepted Answer

A)  a DNA polymerase that is primarily a repair enzyme 
B)  a primase 
C)  a DNA ligase 
D)  a DNA polymerase that is a main polymerizing enzyme 
A)  a DNA polymerase that is primarily a repair enzyme 
B)  a primase 
C)  a DNA ligase 
D)  a DNA polymerase that is a main polymerizing enzyme

Question 3

The production of RNA on a DNA template is called

Accepted Answer

A)  replication. 
B)  transcription. 
C)  translation. 
D)  nucleation. 
A)  replication. 
B)  transcription. 
C)  translation. 
D)  nucleation.

Question 4

E. coli replication on the lagging strand

Accepted Answer

A)  is carried out by DNA polymerase I 
B)  is initially synthesized as Okazaki fragments 
C)  is synthesized continuously 
D)  has this DNA strand synthesized in a 3' → 5' direction 
A)  is carried out by DNA polymerase I 
B)  is initially synthesized as Okazaki fragments 
C)  is synthesized continuously 
D)  has this DNA strand synthesized in a 3' → 5' direction

Question 5

Which of the following mechanisms allow repair enzymes to distinguish incorrect bases in DNA?

Accepted Answer

A)  The newly synthesized strand of DNA lacks methylated bases and other modifications. 
B)  Deamination of A and C lead to improper bases for DNA. 
C)  Thymine dimers and other cross links kink the DNA and are easy to find. 
D)  All of these mechanisms allow repair enzymes to distinguish which base is incorrect. 
A)  The newly synthesized strand of DNA lacks methylated bases and other modifications. 
B)  Deamination of A and C lead to improper bases for DNA. 
C)  Thymine dimers and other cross links kink the DNA and are easy to find. 
D)  All of these mechanisms allow repair enzymes to distinguish which base is incorrect.

Question 6

Exhibit 10A Consider the following diagrams showing a replication fork moving from left to right. The thick lines represent the template\parental strands. The 5' and 3' represent the ends of those template\parental strands.   Refer to Exhibit 10A. Which Okazaki fragment was synthesized earliest?

Accepted Answer

A)  A 
B)  B 
C)  C 
D)  D 
A)  A 
B)  B 
C)  C 
D)  D

Question 7

Both eukaryotes and prokaryotes use a dimeric DNA Polymerase for DNA replication.

Accepted Answer

A) True 
 B)False

Question 8

In prokaryotic replication, all DNA polymerases are capable of all of the following tasks except:

Accepted Answer

A)  Reading a template strand and putting the complementary base in the correct position 
B)  Polymerizing DNA in the 5' to 3' direction 
C)  Excising DNA in the 3' to 5' direction 
D)  Excising DNA in the 5' to 3' direction 
E)  All of these are capabilities of all DNA polymerases 
A)  Reading a template strand and putting the complementary base in the correct position 
B)  Polymerizing DNA in the 5' to 3' direction 
C)  Excising DNA in the 3' to 5' direction 
D)  Excising DNA in the 5' to 3' direction 
E)  All of these are capabilities of all DNA polymerases

Question 9

Why is thymine used in DNA rather than uracil?

Accepted Answer

A)  Thymine is more hydrophobic, so it stacks better in the helix. 
B)  If cytosine is deaminated, it forms uracil, which can be easily distinguished from thymine. 
C)  Thymine is not capable of wobbling, so it pairs more accurately than uracil. 
D)  All of these are correct. 
A)  Thymine is more hydrophobic, so it stacks better in the helix. 
B)  If cytosine is deaminated, it forms uracil, which can be easily distinguished from thymine. 
C)  Thymine is not capable of wobbling, so it pairs more accurately than uracil. 
D)  All of these are correct.

Question 10

Single strand binding proteins are important for this activity:

Accepted Answer

A)  Prevent single-stranded DNA from rewinding. 
B)  Protect single-stranded DNA from enzymatic degradation. 
C)  Prevent double helical DNA from unwinding. 
D)  Prevent double helical DNA from becoming a triple helix. 
E)  Prevent single-stranded DNA from rewinding and protect it from degradation. 
A)  Prevent single-stranded DNA from rewinding. 
B)  Protect single-stranded DNA from enzymatic degradation. 
C)  Prevent double helical DNA from unwinding. 
D)  Prevent double helical DNA from becoming a triple helix. 
E)  Prevent single-stranded DNA from rewinding and protect it from degradation.

Question 11

Which of the following statements is true about the so-called "MUT" (for "mutation") repair mechanisms?

Accepted Answer

A)  Depend on the methylation of old strands of DNA to determine which strand to repair. 
B)  Often remove hundreds or even thousands of bases during the repair process. 
C)  Can only repair mismatches that occur during the normal replication process. 
D)  All of these are true. 
A)  Depend on the methylation of old strands of DNA to determine which strand to repair. 
B)  Often remove hundreds or even thousands of bases during the repair process. 
C)  Can only repair mismatches that occur during the normal replication process. 
D)  All of these are true.

Which of the following repair mechanisms would most likely be used to repair a G in DNA damaged by oxidation?

Which is most likely to have a high processivity?

The production of RNA on a DNA template is called

E. coli replication on the lagging strand

Which of the following mechanisms allow repair enzymes to distinguish incorrect bases in DNA?

Both eukaryotes and prokaryotes use a dimeric DNA Polymerase for DNA replication.

In prokaryotic replication, all DNA polymerases are capable of all of the following tasks except:

Why is thymine used in DNA rather than uracil?

Single strand binding proteins are important for this activity:

Which of the following statements is true about the so-called "MUT" (for "mutation") repair mechanisms?

Biochemistry and the Organization of Cells

Water the Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins Enzymes

The Behavior of Proteins Enzymes Mechanisms and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids How Structure Conveys Information

Transcription of the Genetic Code the Biosynthesis of Rna

Protein Synthesis Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses Cancer and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism Cellular Signaling

Filters

Exam 10: Biosynthesis of Nucleic Acids Replication

Which of the following repair mechanisms would most likely be used to repair a G in DNA damaged by oxidation?

Which is most likely to have a high processivity?

The production of RNA on a DNA template is called

E. coli replication on the lagging strand

Which of the following mechanisms allow repair enzymes to distinguish incorrect bases in DNA?

Exhibit 10A Consider the following diagrams showing a replication fork moving from left to right. The thick lines represent the template\parental strands. The 5' and 3' represent the ends of those template\parental strands. Refer to Exhibit 10A. Which Okazaki fragment was synthesized earliest?

Both eukaryotes and prokaryotes use a dimeric DNA Polymerase for DNA replication.

In prokaryotic replication, all DNA polymerases are capable of all of the following tasks except:

Why is thymine used in DNA rather than uracil?

Single strand binding proteins are important for this activity:

Which of the following statements is true about the so-called "MUT" (for "mutation") repair mechanisms?

Biochemistry and the Organization of Cells

Water the Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins Enzymes

The Behavior of Proteins Enzymes Mechanisms and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids How Structure Conveys Information

Transcription of the Genetic Code the Biosynthesis of Rna

Protein Synthesis Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses Cancer and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism Cellular Signaling

Filters