Exam 6: The Cellular Basis for Mendelian Genetics

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The kinetochore consists of proteins attached to the centromere of the chromosome.

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Match the missing words in the following phrase. Microtubules consist of alpha-tubulin and beta-tubulin. Microtubules are polar, with alpha-tubulin at the [A] end and beta-tubulin at the [B] end. Microtubules attach to the [C] and originate from the [D].

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a. A = minus
b. B = plus
c. C = centromere
d. D = centrosome

What is chromosome pairing?

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Chromosomes align at the metaphase plate before separating at anaphase. Which of the following factors keep chromosomes together at metaphase? Please select all that apply.

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Put the following events in order of occurrence, beginning with the start of G1 phase. -DNA replication

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Double-strand breaks (DSB) are needed for crossing-over to occur in meiosis. In a pair of homologous chromosomes, how many chromatids require a DSB in order for crossing over to occur?

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Put the following events in order of occurrence, beginning with the start of G1 phase. -Aster formation

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Put the steps of meiotic recombination in the correct order -strand invasion

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Put the steps of meiotic recombination in the correct order -DNA double-strand break

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The two kinetochores on one homologue face in opposite directions in meiosis I and face in the same direction in meiosis II.

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Put the following events in order of occurrence, beginning with the start of G1 phase. -Chromosome separation

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Match the missing words in the following phrase. Normal meiosis results in each gamete receiving a normal number of chromosomes - resulting offspring are [A]. When chromosomes or chromatids fail to separate properly during meiosis, gametes can receive one extra copy of a chromosome - this is [B] - or be missing one copy - this is [C]. Any resulting organism is then [D].

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Which of the following differ between oogenesis and spermatogenesis in humans? Please select all that apply.

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Put the steps of meiotic recombination in the correct order -DNA synthesis

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What is a tetrad?

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Which part of meiosis explains Mendel's Law of Segregation at the chromosome level?

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Which of the following statements about meiosis and mitosis are true? Please select all that apply.

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Which phase of the cell cycle has two copies of the genome in the cell for the entire phase?

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Which of the statements about autopolyploids and allopolyploids are true? Please select all that apply.

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Put the following events in order of occurrence, beginning with the start of G1 phase. -Centrosome separation

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