Exam 12: The Biology of Learning and Memory

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​What does the phrase "all parts of the cortex contribute equally to complex behaviors such as learning" define?

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​Briefly describe how LTP occurs,including how glutamate and its receptors are involved.

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​LTP begins with the rapid stimulation of a dendrite,for several seconds.Release of glutamate stimulates AMPA receptors that depolarize the membrane.Then,NMDA receptors become responsive to glutamate and calcium enters the cell to activate CaMKII,which produces a series of cellular changes that maintain LTP.

​Alzheimer's is associated with brain damage as a result of ____.

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​A burst of intense stimulation to a dendrite by one or more axons connected to it in a rapid series can be described as the ____.

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​In searching for the engram,Karl Lashley found that removal of larger areas of cortex resulted in the greatest impairment of memory.

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​Individuals with Korsakoff's syndrome are similar to people with damage to the ____.

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​When Penfield stimulated the temporal cortex of alert and awake brain surgery patients,he found that they ____.

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​Lashley trained rats on a variety of mazes,then made deep cuts in their cortexes.He found that the cuts produced ____.

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​There is compelling evidence for the role of the hippocampus in ____ memory.

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​Damage to the ____ produces symptoms similar to Korsakoff's syndrome.

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​A distinctive symptom of Korsakoff's syndrome is ____.

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​What is a major advantage of Aplysia for studies on the physiology of learning?

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​A distinctive symptom of Korsakoff's syndrome is confabulation,in which patients guess to fill in memory gaps.

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​What is confabulation?

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​The most common treatment for Alzheimer's disease is to give drugs that stimulate ____.

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​Nearly simultaneous stimulation by two or more axons produces LTP,whereas stimulation by just one produces it weakly,if at all.This is known as the property of ____.

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​Habituation and sensitization differ depending upon whether ____.

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​H.M.was unable to form any kind of new memories after his surgery.

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​____ is an influence of recent experience on behavior,even if one does not recognize that influence.

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​Eye-blink conditioning depends on the lateral interpositus nucleus.

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