Question 1

Bioinformatics is _________.

Accepted Answer

A)  the application of information science to biology 
B)  the computational branch of molecular biology 
C)  about searching vast biological databases available on the internet 
D)  using computational tools to compare nucleic acid sequences and protein sequences 
E)  all of the above 
A)  the application of information science to biology 
B)  the computational branch of molecular biology 
C)  about searching vast biological databases available on the internet 
D)  using computational tools to compare nucleic acid sequences and protein sequences 
E)  all of the above

Question 2

A prokaryotic coding sequence includes information on coordinates of the ____ .
I. promoter elements
II. ribosome binding site (RBS)
III. open reading frame (ORF)
IV. introns

Accepted Answer

A)  I and II 
B)  I and III 
C)  II and IV 
D)  I, II and III 
E)  III and IV 
A)  I and II 
B)  I and III 
C)  II and IV 
D)  I, II and III 
E)  III and IV

Question 3

The _________ is the collection of all of the RNA molecules in an organism, cell, or tissue.

Accepted Answer

A)  proteome 
B)  transcriptome 
C)  lipidome 
D)  interactome 
E)  kinome 
A)  proteome 
B)  transcriptome 
C)  lipidome 
D)  interactome 
E)  kinome

Question 4

________ are made with short nucleotide sequences that are used as probes. The abundance of transcripts in a sample is determined by binding _____ transcripts to the probes and detecting the intensity of the signal.

Accepted Answer

A)  Microarrays; fluorescently-labeled 
B)  Slides; color-coded 
C)  Tags; fluorescently-labeled 
D)  Samples; color-coded 
E)  none of the above 
A)  Microarrays; fluorescently-labeled 
B)  Slides; color-coded 
C)  Tags; fluorescently-labeled 
D)  Samples; color-coded 
E)  none of the above

Question 5

ExPASy is a bioinformatics website that contains numerous tools. Among them is the ProtParam tool,
Https://web.expasy.org/protparam/. Go to this site, type in the amino acid sequence without spaces, and calculate some physical and chemical parameters for the following peptide sequence:
  Choose the correct answers from the list given.
I. theoretical pI 6.90
II. molecular weight 3430 (g/mol or DA)
III. number of negatively charged residues (Asp + Glu) is 4
IV. number of proline residues is 3
V. number of histidine residues is 3

Accepted Answer

A)  I and II 
B)  I and III 
C)  II and IV 
D)  III and V 
E)  II and V 
A)  I and II 
B)  I and III 
C)  II and IV 
D)  III and V 
E)  II and V

Question 6

A _______ can be a protein that is either increased in concentration or might be misfolded in a disease state and can help in diagnosing a disease.

Accepted Answer

A)  biomarker 
B)  sequence 
C)  cluster 
D)  fluorescent probe 
E)  dye 
A)  biomarker 
B)  sequence 
C)  cluster 
D)  fluorescent probe 
E)  dye

Question 7

The term _____ refers to study of the structure, function, and evolution of all the genes of an organism.

Accepted Answer

A)  lipidomics 
B)  proteomics 
C)  genomics 
D)  metabolomics 
E)  all of the above 
A)  lipidomics 
B)  proteomics 
C)  genomics 
D)  metabolomics 
E)  all of the above

Question 8

______can detect novel gene transcripts, gene fusions, and single-nucleotide variants.

Accepted Answer

A)  Microarray technology 
B)  RNA sequencing 
C)  DNA sequencing 
D)  PCR 
E)  none of the above 
A)  Microarray technology 
B)  RNA sequencing 
C)  DNA sequencing 
D)  PCR 
E)  none of the above

Question 9

Bioinformatics has developed as a distinct field due to _______.

Accepted Answer

A)  solving the human genome 
B)  advances in software and computing power 
C)  implementation of high-throughput nucleic acid sequencing techniques 
D)  advances in mass spectrometry techniques that make it possible to analyze large molecules 
E)  all of the above 
A)  solving the human genome 
B)  advances in software and computing power 
C)  implementation of high-throughput nucleic acid sequencing techniques 
D)  advances in mass spectrometry techniques that make it possible to analyze large molecules 
E)  all of the above

Bioinformatics is _________.

A prokaryotic coding sequence includes information on coordinates of the ____ . I. promoter elements II. ribosome binding site (RBS) III. open reading frame (ORF) IV. introns

The _________ is the collection of all of the RNA molecules in an organism, cell, or tissue.

____ are made with short nucleotide sequences that are used as probes. The abundance of transcripts in a sample is determined by binding _ transcripts to the probes and detecting the intensity of the signal.

A _______ can be a protein that is either increased in concentration or might be misfolded in a disease state and can help in diagnosing a disease.

The term _____ refers to study of the structure, function, and evolution of all the genes of an organism.

______can detect novel gene transcripts, gene fusions, and single-nucleotide variants.

Bioinformatics has developed as a distinct field due to _______.

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Protein

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

Exam 22: Bioinformatics and Omics

Bioinformatics is _________.

A prokaryotic coding sequence includes information on coordinates of the ____ . I. promoter elements II. ribosome binding site (RBS) III. open reading frame (ORF) IV. introns

The _________ is the collection of all of the RNA molecules in an organism, cell, or tissue.

________ are made with short nucleotide sequences that are used as probes. The abundance of transcripts in a sample is determined by binding _____ transcripts to the probes and detecting the intensity of the signal.

A _______ can be a protein that is either increased in concentration or might be misfolded in a disease state and can help in diagnosing a disease.

The term _____ refers to study of the structure, function, and evolution of all the genes of an organism.

______can detect novel gene transcripts, gene fusions, and single-nucleotide variants.

Bioinformatics has developed as a distinct field due to _______.

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Protein

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

____ are made with short nucleotide sequences that are used as probes. The abundance of transcripts in a sample is determined by binding _ transcripts to the probes and detecting the intensity of the signal.