Exam 12: Peptides, Proteins, and Enzymes

Globular proteins in water typically assume their specific shapes because

Hydrogen bonding plays a role in the primary structure of protein.

Which is a means of denaturing a protein?

Because amino acids contain polar covalent bonds, they are hydrophilic and will dissolve water.

A contributing factor to the tertiary structure of a protein is a covalent bond between two atoms of ___.

The amide bond between two amino acids is referred to as a ___ bond.

___ are inactive enzyme precursors that are synthesized, stored and may be activated where needed.

The ___ is the location on the protein molecule where enzyme catalyzed reactions take place.

Which is an $\alpha$ -amino acid?

A characteristic of a Michaelis-Menten enzyme is that it

The side chain of the amino acid histidine is shown here. The side chain is classified as ___.

The element found in the center of the heme prosthetic group is ___.

Given the following amino acids and their R groups: glycine (R group is -H) - aspartic acid (R group is -CH₂COO^-) cysteine (R group is -CH₂SH) - lysine (R group is -(CH₂)₄NH₃⁺) Sketch aspartic acid.

Shown here is the amino acid glycine at a pH of ___.

The structure of the dipeptide, Phe-Gly, in a solution of pH 14 is ___.

Enzymes that are composed of more than one peptide chain and for which binding of a substrate to one active site affects the bonding of the substrate to other active sites are referred to as a(n) ___ enzyme(s).

A characteristic that distinguishes between secondary and tertiary structures is the fact that hydrogen bonding in all secondary structures are between backbone -C=O and H-N- groups.

Which of the following do not contribute to the overall stability of a tertiary structure of proteins?

Aspartic acid is classified as a polar-acidic amino acid due to

The side chain of the amino acid phenylalanine is shown here. The side chain is classified as ___.