Question 1

Why would the inhibition of osteoclast activity be beneficial in the treatment of osteoporosis?

Accepted Answer

A) It increases calcium in the blood to help promote bone formation. 
B) It inhibits osteolysis. 
C) It allows for an increased production of bone-forming enzymes. 
D) It stimulates osteolysis because osteoclast activity is inhibited. 
A) It increases calcium in the blood to help promote bone formation. 
B) It inhibits osteolysis. 
C) It allows for an increased production of bone-forming enzymes. 
D) It stimulates osteolysis because osteoclast activity is inhibited. B

Question 2

MATCHING
Match the following trade and generic drug names.
-Fosamax

Accepted Answer

A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate 
A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate C

Question 3

Which of the following can be administered intranasally?

Accepted Answer

A) Calcitonin 
B) Raloxifene 
C) Estropipate 
D) Pamidronate 
A) Calcitonin 
B) Raloxifene 
C) Estropipate 
D) Pamidronate A

Question 4

Which of the following is a genetically engineered form of human PTH and carries a serious risk for developing osteosarcoma?

Accepted Answer

A) Raloxifene 
B) Risedronate 
C) Teriparatide 
D) Calcitonin 
A) Raloxifene 
B) Risedronate 
C) Teriparatide 
D) Calcitonin

Question 5

Which of the following is not responsible for the regulation of serum calcium levels?

Accepted Answer

A) Parathyroid hormone (PTH) 
B) Calcitonin 
C) Vitamin A 
D) Vitamin D 
A) Parathyroid hormone (PTH) 
B) Calcitonin 
C) Vitamin A 
D) Vitamin D

Question 6

MATCHING
Match the following trade and generic drug names.
-Aredia

Accepted Answer

A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate 
A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate

Question 7

Fractures caused by osteoporosis when coughing or sneezing are classified as _____ fractures.

Accepted Answer

A) low-impact 
B) bone density 
C) spinal 
D) fragility 
A) low-impact 
B) bone density 
C) spinal 
D) fragility

Question 8

Vitamin _____ is involved in the formation of osteoclasts.

Accepted Answer

A) A 
B) B 
C) C 
D) D 
A) A 
B) B 
C) C 
D) D

Question 9

Of the following,which drug is the least potent bisphosphonate?

Accepted Answer

A) Etidronate 
B) Alendronate 
C) Risedronate 
D) Pamidronate 
A) Etidronate 
B) Alendronate 
C) Risedronate 
D) Pamidronate

Question 10

MATCHING
Match the following trade and generic drug names.
-Didronel

Accepted Answer

A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate 
A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate

Question 11

Calcium _____ is most absorbable and easiest to tolerate.

Accepted Answer

A) carbonate 
B) citrate 
C) gluconate 
D) chloride 
A) carbonate 
B) citrate 
C) gluconate 
D) chloride

Question 12

Raloxifene is indicated for the treatment and prevention of osteoporosis in _____ women.

Accepted Answer

A) perimenopausal 
B) menopausal 
C) postmenopausal 
D) geriatric 
A) perimenopausal 
B) menopausal 
C) postmenopausal 
D) geriatric

Question 13

Why would hyperparathyroidism cause osteoporosis?

Accepted Answer

A) Promotes calcium to be released from bones,causing an increased level of calcium in blood 
B) Blocks the pathway in which calcium is absorbed through the gastrointestinal (GI)tract 
C) Hinders the release of estrogen,which inhibits bone formation 
D) Decreases the ability of calcium to be reabsorbed into the bone 
A) Promotes calcium to be released from bones,causing an increased level of calcium in blood 
B) Blocks the pathway in which calcium is absorbed through the gastrointestinal (GI)tract 
C) Hinders the release of estrogen,which inhibits bone formation 
D) Decreases the ability of calcium to be reabsorbed into the bone

Question 14

Which of the following should have a "Take on an empty stomach" warning label?

Accepted Answer

A) Ibandronate 
B) Raloxifene 
C) Teriparatide 
D) Estradiol 
A) Ibandronate 
B) Raloxifene 
C) Teriparatide 
D) Estradiol

Question 15

A chronic,progressive disease of bone characterized by loss of bone density and bone strength and resulting in increased fracture risk is called _____.

Accepted Answer

A) rheumatoid arthritis (R
A)  
B) osteoporosis 
C) brittle bone disease 
D) osteosarcoma 
A) rheumatoid arthritis (R
A)  
B) osteoporosis 
C) brittle bone disease 
D) osteosarcoma

Question 16

Which of the following must be administered by intravenous (IV)infusion?

Accepted Answer

A) Etidronate 
B) Tiludronate 
C) Risedronate 
D) Pamidronate 
A) Etidronate 
B) Tiludronate 
C) Risedronate 
D) Pamidronate

Question 17

The precursor to osteoporosis is ______.

Accepted Answer

A) osteopenia 
B) osteoblastosis 
C) osteosarcoma 
D) osteoma 
A) osteopenia 
B) osteoblastosis 
C) osteosarcoma 
D) osteoma

Question 18

MATCHING
Match the following trade and generic drug names.
-Evista

Accepted Answer

A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate 
A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate

Question 19

What can be the extent of damage of Paget's disease on the body?

Accepted Answer

A) Affects the limbs only 
B) Entire skeleton may be affected 
C) Affects only joints 
D) Affects only the hips 
A) Affects the limbs only 
B) Entire skeleton may be affected 
C) Affects only joints 
D) Affects only the hips

Question 20

MATCHING
Match the following trade and generic drug names.
-Reclast

Accepted Answer

A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate 
A) Raloxifene 
B) Etidronate 
C) Alendronate 
D) Zoledronic acid 
E) Pamidronate

Exam 16: Treatment of Osteoporosis and Pagets Disease of the Bone

Why would the inhibition of osteoclast activity be beneficial in the treatment of osteoporosis?

MATCHING Match the following trade and generic drug names. -Fosamax

Which of the following can be administered intranasally?

Which of the following is a genetically engineered form of human PTH and carries a serious risk for developing osteosarcoma?

Which of the following is not responsible for the regulation of serum calcium levels?

MATCHING Match the following trade and generic drug names. -Aredia

Fractures caused by osteoporosis when coughing or sneezing are classified as _____ fractures.

Vitamin _____ is involved in the formation of osteoclasts.

Of the following,which drug is the least potent bisphosphonate?

MATCHING Match the following trade and generic drug names. -Didronel

Calcium _____ is most absorbable and easiest to tolerate.

Raloxifene is indicated for the treatment and prevention of osteoporosis in _____ women.

Why would hyperparathyroidism cause osteoporosis?

Which of the following should have a "Take on an empty stomach" warning label?

A chronic,progressive disease of bone characterized by loss of bone density and bone strength and resulting in increased fracture risk is called _____.

Which of the following must be administered by intravenous (IV)infusion?

The precursor to osteoporosis is ______.

MATCHING Match the following trade and generic drug names. -Evista

What can be the extent of damage of Paget's disease on the body?

MATCHING Match the following trade and generic drug names. -Reclast

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

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