Question 1

Cancer-causing chemicals called _____ are found in the workplace,home,and the environment through pollution.

Accepted Answer

A) teratogens 
B) mutagens 
C) carcinogens 
D) hemogens 
A) teratogens 
B) mutagens 
C) carcinogens 
D) hemogens C

Question 2

Which of the following anthracyclines is a prodrug with a long half-life allowing it be administered weekly or monthly?

Accepted Answer

A) Idarubicin 
B) Epirubicin 
C) Doxorubicin 
D) Mitoxantrone 
A) Idarubicin 
B) Epirubicin 
C) Doxorubicin 
D) Mitoxantrone C

Question 3

All chemotherapy agents are prepared in a _____ biohazard safety cabinet containing a high-efficiency particulate air (HEPA)filter with a _____ flow of air.

Accepted Answer

A) Class III,horizontal 
B) Class I,vertical 
C) Class I,horizontal 
D) Class II,vertical 
A) Class III,horizontal 
B) Class I,vertical 
C) Class I,horizontal 
D) Class II,vertical D

Question 4

_____ is used to treat inoperable,metastatic endometrial cancer and renal cell cancer.

Accepted Answer

A) Megestrol 
B) Medroxyprogesterone acetate 
C) Mitomycin 
D) Myleran 
A) Megestrol 
B) Medroxyprogesterone acetate 
C) Mitomycin 
D) Myleran

Question 5

Paclitaxel and docetaxel are cytotoxic drugs that are naturally derived from the _____ yew and _____ yew trees.

Accepted Answer

A) Western,European 
B) Pacific,European 
C) European,American 
D) Western,American 
A) Western,European 
B) Pacific,European 
C) European,American 
D) Western,American

Question 6

How does MTX cause cells to die?

Accepted Answer

A) MTX depletes the necessary amino acids to cease DNA synthesis. 
B) It forms abnormal nucleic acid pairs by inhibiting the formation of cancerous cell walls. 
C) It inhibits DNA synthesis by diminishing essential DNA nucleosides. 
D) It causes cell mutations,inhibiting further replication. 
A) MTX depletes the necessary amino acids to cease DNA synthesis. 
B) It forms abnormal nucleic acid pairs by inhibiting the formation of cancerous cell walls. 
C) It inhibits DNA synthesis by diminishing essential DNA nucleosides. 
D) It causes cell mutations,inhibiting further replication.

Question 7

Examples of ionizing radiation include all of the following except _____.

Accepted Answer

A) x-rays 
B) ultraviolet (UV)light 
C) radon gas 
D) PCBs 
A) x-rays 
B) ultraviolet (UV)light 
C) radon gas 
D) PCBs

Question 8

Why are alkylating agents toxic to cancer cells and noncancer cells?

Accepted Answer

A) They destroy all pathways of ribonucleic acid (RN
A) ,including noncancerous cells. 
B) They damage necessary enzymes to cease DNA synthesis in all cells. 
C) They damage DNA and impair DNA replication. 
D) Alkylating agents are one of the few classes that are toxic only to cancer cells. 
A) They destroy all pathways of ribonucleic acid (RN
A) ,including noncancerous cells. 
B) They damage necessary enzymes to cease DNA synthesis in all cells. 
C) They damage DNA and impair DNA replication. 
D) Alkylating agents are one of the few classes that are toxic only to cancer cells.

Question 9

Lymphoma's primary site of growth begins in the _____.

Accepted Answer

A) cells of the immune system 
B) blood-forming tissues 
C) tissues covering the internal organs 
D) white blood cells 
A) cells of the immune system 
B) blood-forming tissues 
C) tissues covering the internal organs 
D) white blood cells

Question 10

A diet that is high in _____ may increase the risk of cancers of the colon,uterus,and prostate.

Accepted Answer

A) carbohydrates 
B) protein 
C) sugars 
D) fats 
A) carbohydrates 
B) protein 
C) sugars 
D) fats

Question 11

_____ can be used to treat metastatic breast cancer in postmenopausal women.

Accepted Answer

A) Bleomycin 
B) Toremifene 
C) Carboplatin 
D) Cisplatin 
A) Bleomycin 
B) Toremifene 
C) Carboplatin 
D) Cisplatin

Question 12

_____ is associated with causing cancer of the cervix.

Accepted Answer

A) EBV 
B) HPV 
C) HIV 
D) HBV 
A) EBV 
B) HPV 
C) HIV 
D) HBV

Question 13

_____ is a miscellaneous cancer drug agent that is approved for the treatment of head and neck cancer.

Accepted Answer

A) Porfimer 
B) Dactinomycin 
C) Mitomycin 
D) Bleomycin 
A) Porfimer 
B) Dactinomycin 
C) Mitomycin 
D) Bleomycin

Question 14

_____ is a platinum compound that used for the treatment of testicular and ovarian cancer.

Accepted Answer

A) Cisplatin 
B) Carboplatin 
C) Oxaliplatin 
D) Capecitabine 
A) Cisplatin 
B) Carboplatin 
C) Oxaliplatin 
D) Capecitabine

Question 15

Methotrexate (MTX)is the principal drug in the _____ class.

Accepted Answer

A) fluoropyrimidine 
B) platinum compound 
C) antimetabolite 
D) topoisomerase inhibitor 
A) fluoropyrimidine 
B) platinum compound 
C) antimetabolite 
D) topoisomerase inhibitor

Question 16

The oldest class of antineoplastic agents is _____.

Accepted Answer

A) phosphamides 
B) alkerans 
C) alkylating agents 
D) phosphorylating agents 
A) phosphamides 
B) alkerans 
C) alkylating agents 
D) phosphorylating agents

Question 17

Two screening tests used for the diagnosis of colorectal cancer are colonoscopy and _____.

Accepted Answer

A) proctoscopy 
B) fecal occult blood test (FOBT) 
C) enteroscopy 
D) stool color test 
A) proctoscopy 
B) fecal occult blood test (FOBT) 
C) enteroscopy 
D) stool color test

Question 18

The most common form of cancer is _____ cancer.

Accepted Answer

A) breast 
B) prostate 
C) lung 
D) cervical 
A) breast 
B) prostate 
C) lung 
D) cervical

Question 19

Vinorelbine,vincristine,and vinblastine are naturally derived from the_____ plant.

Accepted Answer

A) foxglove 
B) aloe 
C) periwinkle 
D) rosehips 
A) foxglove 
B) aloe 
C) periwinkle 
D) rosehips

Question 20

Which of the following is given intramuscularly after antiestrogen therapy for estrogen receptor (ER)-positive metastatic breast cancer in postmenopausal women with disease progression?

Accepted Answer

A) Fulvestrant 
B) Exemestane 
C) Goserelin 
D) Megestrol acetate 
A) Fulvestrant 
B) Exemestane 
C) Goserelin 
D) Megestrol acetate

Exam 37: Treatment of Cancers

Cancer-causing chemicals called _____ are found in the workplace,home,and the environment through pollution.

Which of the following anthracyclines is a prodrug with a long half-life allowing it be administered weekly or monthly?

All chemotherapy agents are prepared in a _____ biohazard safety cabinet containing a high-efficiency particulate air (HEPA)filter with a _____ flow of air.

_____ is used to treat inoperable,metastatic endometrial cancer and renal cell cancer.

Paclitaxel and docetaxel are cytotoxic drugs that are naturally derived from the _____ yew and _____ yew trees.

How does MTX cause cells to die?

Examples of ionizing radiation include all of the following except _____.

Why are alkylating agents toxic to cancer cells and noncancer cells?

Lymphoma's primary site of growth begins in the _____.

A diet that is high in _____ may increase the risk of cancers of the colon,uterus,and prostate.

_____ can be used to treat metastatic breast cancer in postmenopausal women.

_____ is associated with causing cancer of the cervix.

_____ is a miscellaneous cancer drug agent that is approved for the treatment of head and neck cancer.

_____ is a platinum compound that used for the treatment of testicular and ovarian cancer.

Methotrexate (MTX)is the principal drug in the _____ class.

The oldest class of antineoplastic agents is _____.

Two screening tests used for the diagnosis of colorectal cancer are colonoscopy and _____.

The most common form of cancer is _____ cancer.

Vinorelbine,vincristine,and vinblastine are naturally derived from the_____ plant.

Which of the following is given intramuscularly after antiestrogen therapy for estrogen receptor (ER)-positive metastatic breast cancer in postmenopausal women with disease progression?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

Treatment of Alzheimers Disease

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

Treatment of Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux, and Peptic Ulcer Disease

Treatment of Irritable Bowel Syndrome, ulcerative Colitis, and Crohns Disease

Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

Treatment of Thyroid Disorders

Treatment of Diabetes Mellitus

Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

Treatment of Viral Infections

Vaccines, Immunomodulators, and Immunosuppressants

Treatment of Fungal Infections

Treatment of Decubitus Ulcers and Burns

Treatment of Acne

Treatment of Eczema and Psoriasis

Treatment of Lice and Scabies

Filters

All chemotherapy agents are prepared in a _ biohazard safety cabinet containing a high-efficiency particulate air (HEPA)filter with a _ flow of air.

Paclitaxel and docetaxel are cytotoxic drugs that are naturally derived from the _ yew and _ yew trees.