Question 1

Which routes of administration can be used to administer heparin and low-molecular-weight heparin?

Accepted Answer

A) Intravenous (IV)and intramuscular (IM) 
B) IV and subcutaneous (SQ) 
C) SL and IM 
D) IV and SL 
A) Intravenous (IV)and intramuscular (IM) 
B) IV and subcutaneous (SQ) 
C) SL and IM 
D) IV and SL B

Question 2

An example of an anticoagulant that is manufactured from pig intestines and cow lungs is _____.

Accepted Answer

A) heparin 
B) warfarin 
C) enoxaparin 
D) thrombin 
A) heparin 
B) warfarin 
C) enoxaparin 
D) thrombin A

Question 3

Which of the following may decrease the effectiveness of warfarin if consumed?

Accepted Answer

A) Spinach 
B) Grapefruit juice 
C) Black eyed peas 
D) Basil 
A) Spinach 
B) Grapefruit juice 
C) Black eyed peas 
D) Basil A

Question 4

Antiplatelet drugs produce their effect by _____.

Accepted Answer

A) interfering with steps in the clot formation process 
B) increasing the formation of clots 
C) dissolving blood clots 
D) decreasing the number of red blood cells 
A) interfering with steps in the clot formation process 
B) increasing the formation of clots 
C) dissolving blood clots 
D) decreasing the number of red blood cells

Question 5

MATCHING
Match the following drugs with their mechanism of action.
-Fibric acid derivatives

Accepted Answer

A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL) 
A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL)

Question 6

How do thrombolytic drugs help dissolve clots?

Accepted Answer

A) Inhibit the production of clotting factors in the blood. 
B) Reduce the effects of natural vitamins found in the body to help form clots. 
C) Inhibit the production of thrombin. 
D) Help increase the digestion of fibrin. 
A) Inhibit the production of clotting factors in the blood. 
B) Reduce the effects of natural vitamins found in the body to help form clots. 
C) Inhibit the production of thrombin. 
D) Help increase the digestion of fibrin.

Question 7

Warfarin works by interfering with the formation of vitamin ___-dependent clotting factors.

Accepted Answer

A) B₃ 
B) K 
C) A 
D) D 
A) B₃ 
B) K 
C) A 
D) D

Question 8

Which of the following is not a mechanism of action for lipid lowering drugs in the treatment of hyperlipidemia?

Accepted Answer

A) They affect cholesterol synthesis. 
B) They eliminate bile. 
C) They act on the HDL mechanism. 
D) They act on the LDL metabolism. 
A) They affect cholesterol synthesis. 
B) They eliminate bile. 
C) They act on the HDL mechanism. 
D) They act on the LDL metabolism.

Question 9

Why is it important to not confuse LMWH and heparin?

Accepted Answer

A) LMWH is more effective than heparin and therefore dosing is much different between LMWH and heparin. 
B) LMWH is dosed less frequently than heparin and so confusing them could increase adverse effects. 
C) Heparin has a higher bioavailability than LMWH and should therefore be dosed accordingly to reduce unwanted adverse effects. 
D) LMWH are highly protein bound and should therefore not be confused. 
A) LMWH is more effective than heparin and therefore dosing is much different between LMWH and heparin. 
B) LMWH is dosed less frequently than heparin and so confusing them could increase adverse effects. 
C) Heparin has a higher bioavailability than LMWH and should therefore be dosed accordingly to reduce unwanted adverse effects. 
D) LMWH are highly protein bound and should therefore not be confused.

Question 10

Of the following risk factors for stroke and myocardial infarctions,which one promotes atherosclerosis,increases clotting factors in the blood,stimulates vasoconstriction,and weakens the endothelial wall?

Accepted Answer

A) Alcohol consumption 
B) Diet 
C) Smoking 
D) Exercise 
A) Alcohol consumption 
B) Diet 
C) Smoking 
D) Exercise

Question 11

After reconstitution,thrombolytic drugs should be stored in the refrigerator and used within ____ hours.

Accepted Answer

A) 12 
B) 24 
C) 36 
D) 48 
A) 12 
B) 24 
C) 36 
D) 48

Question 12

Match the following trade names with their generic names.
-Zetia

Accepted Answer

A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe 
A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe

Question 13

Why would increasing high-density lipoproteins (HDL)levels be beneficial when treating atherosclerosis?

Accepted Answer

A) HDL acts as an antioxidant,reducing inflammation. 
B) HDL carries unsaturated fats in the blood. 
C) HDL increases low-density lipoprotein (LDL)oxidation. 
D) HDL helps digest trans fats and carries them to the liver to be eliminated. 
A) HDL acts as an antioxidant,reducing inflammation. 
B) HDL carries unsaturated fats in the blood. 
C) HDL increases low-density lipoprotein (LDL)oxidation. 
D) HDL helps digest trans fats and carries them to the liver to be eliminated.

Question 14

MATCHING
Match the following drugs with their mechanism of action.
-Bile acid sequestrants

Accepted Answer

A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL) 
A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL)

Question 15

Which of the following may be used to treat a heparin overdose?

Accepted Answer

A) Aspart protamine 
B) Vitamin D 
C) Vitamin K 
D) Protamine sulfate 
A) Aspart protamine 
B) Vitamin D 
C) Vitamin K 
D) Protamine sulfate

Question 16

Match the following trade names with their generic names.
-Tricor

Accepted Answer

A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe 
A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe

Question 17

_____ is triggered by atherosclerosis and can also cause clogged arteries.

Accepted Answer

A) Aneurysm 
B) Arteriosclerosis 
C) Atherothrombosis 
D) Arteriofibrosis 
A) Aneurysm 
B) Arteriosclerosis 
C) Atherothrombosis 
D) Arteriofibrosis

Question 18

Match the following trade names with their generic names.
-Lovenox

Accepted Answer

A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe 
A) Fenofibrate 
B) Enoxaparin 
C) Simvastatin 
D) Clopidogrel 
E) Ezetimibe

Question 19

MATCHING
Match the following drugs with their mechanism of action.
-Nicotinic acid derivatives

Accepted Answer

A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL) 
A) Most effective at increasing HDL 
B) Promote intestinal clearance of cholesterol 
C) Most effective at lowering LDL 
D) Increase clearance of very-low-density lipoprotein (VLDL)

Question 20

Drugs that control the rate of clot formation and clot dissolution are classified as _____ and can prevent stroke and myocardial infarction.

Accepted Answer

A) anticoagulants 
B) antithrombotics 
C) antilipidemics 
D) cardiolytics 
A) anticoagulants 
B) antithrombotics 
C) antilipidemics 
D) cardiolytics

Exam 24: Treatment of Myocardial Infarction and Stroke

Which routes of administration can be used to administer heparin and low-molecular-weight heparin?

An example of an anticoagulant that is manufactured from pig intestines and cow lungs is _____.

Which of the following may decrease the effectiveness of warfarin if consumed?

Antiplatelet drugs produce their effect by _____.

MATCHING Match the following drugs with their mechanism of action. -Fibric acid derivatives

How do thrombolytic drugs help dissolve clots?

Warfarin works by interfering with the formation of vitamin ___-dependent clotting factors.

Which of the following is not a mechanism of action for lipid lowering drugs in the treatment of hyperlipidemia?

Why is it important to not confuse LMWH and heparin?

Of the following risk factors for stroke and myocardial infarctions,which one promotes atherosclerosis,increases clotting factors in the blood,stimulates vasoconstriction,and weakens the endothelial wall?

After reconstitution,thrombolytic drugs should be stored in the refrigerator and used within ____ hours.

Match the following trade names with their generic names. -Zetia

Why would increasing high-density lipoproteins (HDL)levels be beneficial when treating atherosclerosis?

MATCHING Match the following drugs with their mechanism of action. -Bile acid sequestrants

Which of the following may be used to treat a heparin overdose?

Match the following trade names with their generic names. -Tricor

_____ is triggered by atherosclerosis and can also cause clogged arteries.

Match the following trade names with their generic names. -Lovenox

MATCHING Match the following drugs with their mechanism of action. -Nicotinic acid derivatives

Drugs that control the rate of clot formation and clot dissolution are classified as _____ and can prevent stroke and myocardial infarction.

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

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