Exam 21: Genomics, bioinformatics, and Proteomics

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Introns are found only in prokaryotic genomes.

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What is meant by the term pseudogene?

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A bacterial polygenic transcription unit ________.

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Multigene families are characterized by clusters of tandemly arranged unique pseudogenes organized as operons.

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How are pseudogenes formed?

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Humans have more DNA and more genes than any other organism.

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What is meant by the term low gene density? Give an example of an organism with low gene density.

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What is one major limitation of two-dimensional gel electrophoresis (2-DGE)?

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The dog (Canis familiaris)genome has recently been sequenced.About how many of the dog's genes are shared with humans?

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Name the two strategic methods that scientists are using to sequence genomes.

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In what way will the discipline called metagenomics contribute to human health and welfare?

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Archaea (formerly known as archaebacteria)is one of the three major divisions of living organisms; the other two are eubacteria and eukaryotes.Speculate on how an organism such as Nanoarchaeum equitans with one of the smallest genomes known,about 0.5 Mb,can complete its life cycle with so little genetic material?

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What is the typical gene density per kilobase in prokaryotes?

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Numerous scientists around the world have proposed to sequence 10,000 vertebrate genomes in five years.What is the name of this plan?

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The terms proteomics and genomics mean essentially the same thing.

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The Human Genome Project,which got under way in 1990,is an international effort to ________.

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What is comparative genomics?

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What is ELSI?

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It appears as if about 5000 functional genes is the minimum genome size necessary for life of a prokaryote.

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Present a general definition for a multigene family and how it relates to a superfamily.

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