Exam 10: Antimicrobial Treatment

Antimicrobials that are effective against a wide variety of microbial types are termed ________.

Drugs with high selective toxicity include ________.

What cell wall inhibiting drug is used in cases of penicillin and methicillin resistance?

A clinical microbiologist makes serial dilutions of several antimicrobials in broth,and then incubates each drug dilution series with a standard amount of a patient's isolated pathogen.What is this microbiologist setting up?

Which drug is used to treat cases of tuberculosis?

The multidrug-resistant pumps in many bacterial cell membranes function by ________.

A ratio of the dose of a drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the ________.

Gram-negative rods are often treated with ________.

Mebendazole is a drug used to treat ________ infections.

Micafungin and caspofungin are antifungal drugs that inhibit cell wall synthesis.  They belong to the group of drugs known as ________.

A 12-year-old male is admitted to the pediatric unit due to persistent upper respiratory symptoms and respiratory distress. The patient has a history of developmental delay, chronic lung disease, and frequent respiratory infections. Upon assessment, the RN notes the patient to have a fever, moderate respiratory rate, productive cough, and large amount of nasal secretions. Upon report from the patient's mother, the patient has been on a 3-week course of antibiotics with no improvement in symptoms. The medical team completes a respiratory infection workup and the patient is diagnosed with bacterial pneumonia and methicillin-resistant Staphylococcus aureus (MRSA) superinfection. -The RN provides education to the patient and his mother regarding the diagnosis.Which of the following statements by the mother demonstrates a proper understanding of the teaching?  

Substances that are naturally produced by certain microorganisms that can inhibit or destroy other microorganisms are called ________.

Fluoroquinolones such as ciprofloxacin,are synthetic drugs that interfere with the action of DNA helicases.  This means that ________.

Which antimicrobial does not interfere with protein synthesis?

A 76-year-old male visits his primary care physician with complaints of burning with urination and a frequent urge to void. The RN aids the patient in collecting a urine specimen to be sent for analysis. While awaiting the final results of drug susceptibility testing in the lab, the patient is prescribed oral sulfasoxazole. -You provide education to the patient regarding sulfasoxazole,a sulfonamide that targets folic acid synthesis.The synthesis of which of the following products is affected by inhibition of folate metabolism?  

Which antimicrobial does not inhibit cell wall synthesis?

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Each of the following affect cell walls except ________.

Which newer synthetic drug is used to treat MRSA and VRE infections?

Bacteria can have a natural resistance to a drug that it has never been exposed to.