Question 1

Which immunoglobulin class/es can fix complement?

Accepted Answer

A) IgM only 
B) IgG only 
C) IgD only 
D) IgM and IgG 
E) IgE and IgA 
A) IgM only 
B) IgG only 
C) IgD only 
D) IgM and IgG 
E) IgE and IgA

Question 2

Antibody molecules can act as enzyme to directly destroy an antigen.

Accepted Answer

A) True 
 B)False

Question 3

The monomer subunit of immunoglobulin molecules has all the following, except

Accepted Answer

A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain. 
A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain.

Question 4

The immunoglobulin class that is the only one capable of crossing the placenta is

Accepted Answer

A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM. 
A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM.

Question 5

Which type of cell is severely depressed in AIDS patients?

Accepted Answer

A) Cytotoxic T cells 
B) Helper T cells 
C) B cells 
D) Plasma cells 
E) Suppressor T cells 
A) Cytotoxic T cells 
B) Helper T cells 
C) B cells 
D) Plasma cells 
E) Suppressor T cells

Question 6

Cytotoxic T cells

Accepted Answer

A) stimulate B cell proliferation. 
B) lack specificity for a target cell. 
C) secrete granzymes and perforins that damage target cells. 
D) secrete interleukin-2 to stimulate B and T cells. 
E) All of the choices are correct. 
A) stimulate B cell proliferation. 
B) lack specificity for a target cell. 
C) secrete granzymes and perforins that damage target cells. 
D) secrete interleukin-2 to stimulate B and T cells. 
E) All of the choices are correct.

Question 7

Which cells direct involvement are required for cell-mediated immunities?

Accepted Answer

A) T-cells 
B) B-cells 
C) Bacterial cells 
D) Viral components 
A) T-cells 
B) B-cells 
C) Bacterial cells 
D) Viral components

Question 8

Which sequence of events is correct for a specific immune response?

Accepted Answer

A) Lymphocyte development, presentation of antigens, antibody production, challenge of B cells. 
B) Lymphocyte development, challenge of B cells, antibody production, presentation of antigens. 
C) Lymphocyte development, presentation of antigens, B cell challenge, antibody production. 
D) Antibody production, lymphocyte production, B cell challenge, presentation of antigens. 
A) Lymphocyte development, presentation of antigens, antibody production, challenge of B cells. 
B) Lymphocyte development, challenge of B cells, antibody production, presentation of antigens. 
C) Lymphocyte development, presentation of antigens, B cell challenge, antibody production. 
D) Antibody production, lymphocyte production, B cell challenge, presentation of antigens.

Question 9

Immune sera is produced in horses for all the following except

Accepted Answer

A) diphtheria. 
B) botulism. 
C) snake bites. 
D) chickenpox. 
E) spider bites. 
A) diphtheria. 
B) botulism. 
C) snake bites. 
D) chickenpox. 
E) spider bites.

Question 10

All of the following are characteristics of IgM, except

Accepted Answer

A) it has 10 antigen binding sites. 
B) it contains a central J chain. 
C) it is the first class synthesized by a plasma cell. 
D) it can fix complement. 
E) it is a dimer. 
A) it has 10 antigen binding sites. 
B) it contains a central J chain. 
C) it is the first class synthesized by a plasma cell. 
D) it can fix complement. 
E) it is a dimer.

Question 11

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Accepted Answer

The answer of A hybridoma results from the fusion of...

Question 12

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Accepted Answer

A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response 
A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response

Question 13

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

Accepted Answer

A) IgM. 
B) IgA. 
C) IgD. 
D) IgE. 
E) IgG. 
A) IgM. 
B) IgA. 
C) IgD. 
D) IgE. 
E) IgG.

Question 14

Cell surface markers involved in immune reactions

Accepted Answer

A) are the result of genetic expression. 
B) function in recognition of self molecules. 
C) receive and transmit chemical messages among other cells of the system. 
D) aid in cellular development. 
E) all of the choices are correct. 
A) are the result of genetic expression. 
B) function in recognition of self molecules. 
C) receive and transmit chemical messages among other cells of the system. 
D) aid in cellular development. 
E) all of the choices are correct.

Question 15

During presentation of APC-bound antigen, macrophages secrete the cytokine, _____, that activates T helper cells.

Accepted Answer

The answer of During presentation of APC-bound antigen, macrophages secrete...

Question 16

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Accepted Answer

A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response 
A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response

Question 17

Properties of effective antigens include all the following, except

Accepted Answer

A) foreign to the immune system. 
B) molecular complexity. 
C) large molecules with a minimum molecular weight of 1,000. 
D) large polymers made up of repeating subunits. 
E) cells or large, complex molecules. 
A) foreign to the immune system. 
B) molecular complexity. 
C) large molecules with a minimum molecular weight of 1,000. 
D) large polymers made up of repeating subunits. 
E) cells or large, complex molecules.

Question 18

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

Accepted Answer

The answer of Certain body sites contain sequestered molecules, called...

Question 19

All of the following are advantages of attenuated vaccines over inactivated vaccines except

Accepted Answer

A) they confer longer lasting protection. 
B) they produce infection but not disease. 
C) they can mutate back to a virulent strain. 
D) they require fewer boosters. 
E) they require smaller doses. 
A) they confer longer lasting protection. 
B) they produce infection but not disease. 
C) they can mutate back to a virulent strain. 
D) they require fewer boosters. 
E) they require smaller doses.

Question 20

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Exam 15: Adaptive, Specific Immunity and Immunization

Which immunoglobulin class/es can fix complement?

Antibody molecules can act as enzyme to directly destroy an antigen.

The monomer subunit of immunoglobulin molecules has all the following, except

The immunoglobulin class that is the only one capable of crossing the placenta is

Which type of cell is severely depressed in AIDS patients?

Cytotoxic T cells

Which cells direct involvement are required for cell-mediated immunities?

Which sequence of events is correct for a specific immune response?

Immune sera is produced in horses for all the following except

All of the following are characteristics of IgM, except

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

Cell surface markers involved in immune reactions

During presentation of APC-bound antigen, macrophages secrete the cytokine, _____, that activates T helper cells.

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Properties of effective antigens include all the following, except

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

All of the following are advantages of attenuated vaccines over inactivated vaccines except

Antibody molecules circulate in lymph, blood, and tissue fluids.

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods of Studying Microorganisms

A Survey of Prokaryotic Cells and Microorganisms

A Survey of Eukaryotic Cells and Microorganisms

An Introduction to Viruses

Microbial Nutrition, Ecology, and Growth

An Introduction to Microbial Metabolism: the Chemical Crossroads of Life

Microbial Genetics

Genetic Engineering: a Revolution in Molecular Biology

Physical and Chemical Agents for Microbial Control

Drugs, Microbes, Host--The Elements of Chemotherapy

Microbe-Human Interactions: Infection and Disease

An Introduction to Host Defenses and Innate Immunities

Disorders in Immunity

Procedures for Identifying Pathogens and Diagnosing Infections

The Gram-Positive and Gram-Negative Cocci of Medical Importance

The Gram-Positive Bacilli of Medical Importance

The Gram-Negative Bacilli of Medical Importance

Miscellaneous Bacterial Agents of Disease

The Fungi of Medical Importance

The Parasites of Medical Importance

Introduction to Viruses That Infect Humans: the Dna Viruses

The Rna Viruses That Infect Humans

Environmental Microbiology

Applied and Industrial Microbiology

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