Exam 21: The Genetic Basis Of Cancer

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What is the role of the tumor suppressor gene in the regulation of the cell cycle? Include in your answer discussion of at least one specific tumor suppressor gene such as pRB.

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What classifies a tumor as being malignant?

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Which of the following is not true regarding cancer?

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Burkitts lymphoma and chronic myelogenous leukemia are associated with which of the following?

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How does the inactivation of mutations in the APC gene initiate tumor formation?

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Why do v-oncs cause cancer whereas normal c-oncs do not?

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Mutations in __________ lead to a failure to repress cell division.

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Outline the killing events that take place during the process of apoptosis and discuss how this process can relate to the formation of cancer.

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Which of the following causes cancer?

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Which statement is not true about checkpoints in the cell cycle?

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Which of the following human behaviors contribute to the risk of cancer?

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Which of the following genes have been implicated in hereditary forms of breast cancer?

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Which of the following is the best example of a tumor-suppressor gene?

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Which statement is not true about the tumor suppressor gene pAPC?

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Mutations in _______ can actively promote cell division.

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CDKs

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Which property is not exhibited by tumor-causing retroviruses?

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The genetic basis for cancer was suspected long before the scientific evidence was uncovered.The suspicion was due to

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The START checkpoint

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Why do c-oncs have introns whereas v-oncs do not; and how would this benefit a retrovirus?

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