Question 1

Which of the following is not a tumor suppressor gene?

Accepted Answer

A)  p16 
B)  c-myc 
C)  RB 
D)  NF2 
E)  TP53 
A)  p16 
B)  c-myc 
C)  RB 
D)  NF2 
E)  TP53

Question 2

Which of the following is true regarding tumor-inducing retroviruses?

Accepted Answer

A)  Retroviruses are double-stranded DNA viruses. 
B)  The enzyme reverse transcriptase is essential for transcribing the viral DNA into RNA. 
C)  Cancer-causing genes encoded by the viral genome are called proto-oncogenes. 
D)  Each type of viral gene that can cause cancer can potentially regulate the expression of cellular genes. 
E)  Viral genes that can cause cancer are different from other viral genes because they possess introns. 
A)  Retroviruses are double-stranded DNA viruses. 
B)  The enzyme reverse transcriptase is essential for transcribing the viral DNA into RNA. 
C)  Cancer-causing genes encoded by the viral genome are called proto-oncogenes. 
D)  Each type of viral gene that can cause cancer can potentially regulate the expression of cellular genes. 
E)  Viral genes that can cause cancer are different from other viral genes because they possess introns.

Question 3

Of the four genes found in the Rous sarcoma virus,which provides tumor suppression ability?

Accepted Answer

A)  Gag 
B)  Env 
C)  Pol 
D)  V-src 
E)  Gag and Env 
A)  Gag 
B)  Env 
C)  Pol 
D)  V-src 
E)  Gag and Env

Question 4

Which of the following is a proto-oncogene implicated in the formation of glioblastomas?

Accepted Answer

A)  EGFR 
B)  PDGF 
C)  AST 
D)  EGFR and PDGF 
E)  All of these 
A)  EGFR 
B)  PDGF 
C)  AST 
D)  EGFR and PDGF 
E)  All of these

Question 5

Where are most of the mutations that inactivate p53 located?

Accepted Answer

A)  N-terminal transcription-activation domain 
B)  Central DNA-binding core domain 
C)  C-terminal homo-oligomerization domain 
D)  D-terminal binding domain 
E)  None of these 
A)  N-terminal transcription-activation domain 
B)  Central DNA-binding core domain 
C)  C-terminal homo-oligomerization domain 
D)  D-terminal binding domain 
E)  None of these

Question 6

How does the START checkpoint regulates cell cycle growth,and what happens when this checkpoint is deregulated? Explain your answer by discussing the appropriate cyclins and CDK molecules and their functions.

Accepted Answer

One of the most important cell-cycle che

Question 7

Mutations in HPC1

Accepted Answer

A)  cause glioblastomas in the brain. 
B)  lead to prostate cancer when mutations in TP53, RB, and NF2 also occur. 
C)  is the gene for the inherited form of prostate cancer. 
D)  require mutations in several other tumor suppressor genes to cause polyposis carcinomas. 
E)  None of these 
A)  cause glioblastomas in the brain. 
B)  lead to prostate cancer when mutations in TP53, RB, and NF2 also occur. 
C)  is the gene for the inherited form of prostate cancer. 
D)  require mutations in several other tumor suppressor genes to cause polyposis carcinomas. 
E)  None of these

Question 8

What are cellular homologues of viral oncogenes called?

Accepted Answer

A)  Non-cellular oncogenes 
B)  Adaptive oncogenes 
C)  Proto-oncogenes 
D)  Pre-oncogenes 
E)  Post-oncogenes 
A)  Non-cellular oncogenes 
B)  Adaptive oncogenes 
C)  Proto-oncogenes 
D)  Pre-oncogenes 
E)  Post-oncogenes

Question 9

Which of the following genes would be considered an oncogene?

Accepted Answer

A)  Gag 
B)  Env 
C)  V-src 
D)  Gag and Env 
E)  All of these are correct. 
A)  Gag 
B)  Env 
C)  V-src 
D)  Gag and Env 
E)  All of these are correct.

Question 10

How do c-ras mutations,like the c-H ras gene,cause cancer?

Accepted Answer

Unlike viral oncogenes,the mutant c-H-ra

Which of the following is not a tumor suppressor gene?

Which of the following is true regarding tumor-inducing retroviruses?

Of the four genes found in the Rous sarcoma virus,which provides tumor suppression ability?

Which of the following is a proto-oncogene implicated in the formation of glioblastomas?

Where are most of the mutations that inactivate p53 located?

How does the START checkpoint regulates cell cycle growth,and what happens when this checkpoint is deregulated? Explain your answer by discussing the appropriate cyclins and CDK molecules and their functions.

Mutations in HPC1

What are cellular homologues of viral oncogenes called?

Which of the following genes would be considered an oncogene?

How do c-ras mutations,like the c-H ras gene,cause cancer?

The Science Of Genetics

Cellular Reproduction

Mendelism The Basic Principles Of Inheritance

Extensions Of Mendelism

The Chromosomal Basis Of Mendelism

Variation In Chromosome Number And Structure

Linkage,Crossing Over,And Chromosome Mapping In …

The Genetics Of Bacteria And Their Viruses

DNA And The Molecular Structure Of Chromosomes

Replication Of DNA And Chromosomes

Transcription And RNA Processing

Translation And The Genetic Code

Mutation,DNA Repair,And Recombination

The Techniques Of Molecular Genetics

Genomics

Applications Of Molecular Genetics

Transposable Genetics Elements

Regulation Of Gene Expression In Prokaryotes

Regulation Of Gene Expression In Eukaryotes

The Genetic Control Of Animal Development

Inheritance Of Complex Traits

Population Genetics

Evolutionary Genetics

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Exam 21: The Genetic Basis Of Cancer

Which of the following is not a tumor suppressor gene?

Which of the following is true regarding tumor-inducing retroviruses?

Of the four genes found in the Rous sarcoma virus,which provides tumor suppression ability?

Which of the following is a proto-oncogene implicated in the formation of glioblastomas?

Where are most of the mutations that inactivate p53 located?

How does the START checkpoint regulates cell cycle growth,and what happens when this checkpoint is deregulated? Explain your answer by discussing the appropriate cyclins and CDK molecules and their functions.

Mutations in HPC1

What are cellular homologues of viral oncogenes called?

Which of the following genes would be considered an oncogene?

How do c-ras mutations,like the c-H ras gene,cause cancer?

The Science Of Genetics

Cellular Reproduction

Mendelism The Basic Principles Of Inheritance

Extensions Of Mendelism

The Chromosomal Basis Of Mendelism

Variation In Chromosome Number And Structure

Linkage,Crossing Over,And Chromosome Mapping In …

The Genetics Of Bacteria And Their Viruses

DNA And The Molecular Structure Of Chromosomes

Replication Of DNA And Chromosomes

Transcription And RNA Processing

Translation And The Genetic Code

Mutation,DNA Repair,And Recombination

The Techniques Of Molecular Genetics

Genomics

Applications Of Molecular Genetics

Transposable Genetics Elements

Regulation Of Gene Expression In Prokaryotes

Regulation Of Gene Expression In Eukaryotes

The Genetic Control Of Animal Development

Inheritance Of Complex Traits

Population Genetics

Evolutionary Genetics

Filters