Question 1

Which of the following best describes the process of mitosis?

Accepted Answer

A)  Cell division by which only one-half of the daughter cells produced are identical to the parent cell 
B)  Cell division of germ cells by which two successive divisions of the nucleus produce cells that contain half the number of chromosomes of somatic cells 
C)  Cell division that produces two daughter cells having the same number of chromosomes as the parent 
D)  Cell division that produces four daughter cells (4n) 
A)  Cell division by which only one-half of the daughter cells produced are identical to the parent cell 
B)  Cell division of germ cells by which two successive divisions of the nucleus produce cells that contain half the number of chromosomes of somatic cells 
C)  Cell division that produces two daughter cells having the same number of chromosomes as the parent 
D)  Cell division that produces four daughter cells (4n) C

Question 2

Which type of genetic change (mutation) is incapable of reverting back to the original phenotype?

Accepted Answer

A)  Duplication 
B)  Deletion 
C)  Recombination 
D)  Insertion 
A)  Duplication 
B)  Deletion 
C)  Recombination 
D)  Insertion B

Question 3

A gene, such as the O gene, that produces no detectable product is called:

Accepted Answer

A)  an amorph. 
B)  a trait. 
C)  an allele. 
D)  recessive. 
A)  an amorph. 
B)  a trait. 
C)  an allele. 
D)  recessive. A

Question 4

Which of the following best describes the structure of human chromosomes?

Accepted Answer

A)  Linear strands of DNA wound around histones 
B)  Linear strands of RNA wrapped around histones 
C)  Tertiary structure of DNA wound around histones 
D)  Quaternary structure of DNA wound around histones 
A)  Linear strands of DNA wound around histones 
B)  Linear strands of RNA wrapped around histones 
C)  Tertiary structure of DNA wound around histones 
D)  Quaternary structure of DNA wound around histones

Question 5

What is a vector?

Accepted Answer

A)  Substance capable of catalyzing a reaction 
B)  Sequence of three bases in a strand of DNA 
C)  Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell 
D)  Substance that can carry an electric current in solution 
A)  Substance capable of catalyzing a reaction 
B)  Sequence of three bases in a strand of DNA 
C)  Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell 
D)  Substance that can carry an electric current in solution

Question 6

How do restriction endonucleases function?

Accepted Answer

A)  Disrupt hydrogen bonding in DNA structure 
B)  Promote digestion of RNA 
C)  Cut DNA into smaller fragments 
D)  Terminate translation of mRNA 
A)  Disrupt hydrogen bonding in DNA structure 
B)  Promote digestion of RNA 
C)  Cut DNA into smaller fragments 
D)  Terminate translation of mRNA

Question 7

A human gamete (egg or sperm) contains how many chromosomes?

Accepted Answer

A)  23 pairs 
B)  46 pairs 
C)  23 chromosomes 
D)  46 chromosomes 
A)  23 pairs 
B)  46 pairs 
C)  23 chromosomes 
D)  46 chromosomes

Question 8

In the MN blood group system, a person who inherits an "M" allele and an "N" allele expresses both M and N antigens on the RBCs. Which of the following is true?

Accepted Answer

A)  M is dominant to N. 
B)  N is dominant to M. 
C)  M an N are codominant alleles. 
D)  M and N are located on the same chromosome. 
A)  M is dominant to N. 
B)  N is dominant to M. 
C)  M an N are codominant alleles. 
D)  M and N are located on the same chromosome.

Question 9

All of the following are consistent with Mendel's basic rules of inheritance except:

Accepted Answer

A)  the gene is transmitted through generations intact. 
B)  a pair of genes is always found in the same gamete. 
C)  different pairs of genes are assorted independently of each other. 
D)  a pair of genes is rarely found in the same gamete. 
A)  the gene is transmitted through generations intact. 
B)  a pair of genes is always found in the same gamete. 
C)  different pairs of genes are assorted independently of each other. 
D)  a pair of genes is rarely found in the same gamete.

Question 10

A triple set of nucleotides is a:

Accepted Answer

A)  helix. 
B)  base. 
C)  codon. 
D)  template. 
A)  helix. 
B)  base. 
C)  codon. 
D)  template.

Question 11

The condition in which one chromosome has a copy of the gene and the other chromosome has that gene deleted or absent is referred to as:

Accepted Answer

A)  homozygous. 
B)  heterozygous. 
C)  hemizygous. 
D)  recessive. 
A)  homozygous. 
B)  heterozygous. 
C)  hemizygous. 
D)  recessive.

Question 12

Which of the following best describes classical genetics?

Accepted Answer

A)  DNA alteration that is caused by a physical or chemical agent 
B)  Transmission of characteristics from parents to offspring 
C)  Possessing a pair of identical alleles 
D)  The synthesis of RNA from DNA requiring RNA polymerase 
A)  DNA alteration that is caused by a physical or chemical agent 
B)  Transmission of characteristics from parents to offspring 
C)  Possessing a pair of identical alleles 
D)  The synthesis of RNA from DNA requiring RNA polymerase

Question 13

In a pedigree analysis, what do vertical lines indicate?

Accepted Answer

A)  Consanguineous mating 
B)  Offspring 
C)  Stillbirth 
D)  Deceased sibling 
A)  Consanguineous mating 
B)  Offspring 
C)  Stillbirth 
D)  Deceased sibling

Question 14

How is it genetically possible for a child to type Rh-negative?

Accepted Answer

A)  Both parents are Dd. 
B)  Both parents are DD. 
C)  Mom is DD and Dad is Dd. 
D)  Sibling is Rh-positive. 
A)  Both parents are Dd. 
B)  Both parents are DD. 
C)  Mom is DD and Dad is Dd. 
D)  Sibling is Rh-positive.

Question 15

Which constituent in the Hardy-Weinberg equation represents the total number of alleles?

Accepted Answer

A)  q 
B)  p 
C)  2pq 
D)  q2 
A)  q 
B)  p 
C)  2pq 
D)  q2

Question 16

A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is:

Accepted Answer

A)  OO 
B)  AA 
C)  AB 
D)  AO 
A)  OO 
B)  AA 
C)  AB 
D)  AO

Question 17

A father carries the Xga trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?

Accepted Answer

A)  Autosomal dominant 
B)  X-linked dominant 
C)  X-linked recessive 
D)  Autosomal recessive 
A)  Autosomal dominant 
B)  X-linked dominant 
C)  X-linked recessive 
D)  Autosomal recessive

Question 18

Which of the following must be true when using the Hardy-Weinberg equation?

Accepted Answer

A)  The population must be large 
B)  Mutations cannot occur 
C)  Mating must occur randomly 
D)  All of the above 
A)  The population must be large 
B)  Mutations cannot occur 
C)  Mating must occur randomly 
D)  All of the above

Question 19

In Mendel's law of separation, the first-filial generation is:

Accepted Answer

A)  recessive. 
B)  homozygous. 
C)  heterozygous. 
D)  autologous. 
A)  recessive. 
B)  homozygous. 
C)  heterozygous. 
D)  autologous.

Question 20

How many chromosomes do somatic cells of humans have?

Accepted Answer

A)  46 
B)  50 
C)  23 
D)  100 
A)  46 
B)  50 
C)  23 
D)  100

Exam 2: Basic Genetics

Which of the following best describes the process of mitosis?

Which type of genetic change (mutation) is incapable of reverting back to the original phenotype?

A gene, such as the O gene, that produces no detectable product is called:

Which of the following best describes the structure of human chromosomes?

What is a vector?

How do restriction endonucleases function?

A human gamete (egg or sperm) contains how many chromosomes?

In the MN blood group system, a person who inherits an "M" allele and an "N" allele expresses both M and N antigens on the RBCs. Which of the following is true?

All of the following are consistent with Mendel's basic rules of inheritance except:

A triple set of nucleotides is a:

The condition in which one chromosome has a copy of the gene and the other chromosome has that gene deleted or absent is referred to as:

Which of the following best describes classical genetics?

In a pedigree analysis, what do vertical lines indicate?

How is it genetically possible for a child to type Rh-negative?

Which constituent in the Hardy-Weinberg equation represents the total number of alleles?

A woman with blood group A marries a man with blood group O. Their firstborn child has blood group O. The mother's most probable genotype is:

A father carries the Xga trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?

Which of the following must be true when using the Hardy-Weinberg equation?

In Mendel's law of separation, the first-filial generation is:

How many chromosomes do somatic cells of humans have?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters

A father carries the Xg^a trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent?