Question 1

When would transfusing non-group-specific blood be warranted?

Accepted Answer

A)  Anti-M that interfered with reverse grouping was present in patient serum 
B)  Anti-B is shown in an A person who has been massively transfused with group O blood 
C)  Anti-A is shown in an A person who has been massively transfused with group O blood 
D)  None of the above 
A)  Anti-M that interfered with reverse grouping was present in patient serum 
B)  Anti-B is shown in an A person who has been massively transfused with group O blood 
C)  Anti-A is shown in an A person who has been massively transfused with group O blood 
D)  None of the above C

Question 2

What does the minor crossmatch consist of?

Accepted Answer

A)  Mixing donor plasma with patient red blood cells 
B)  Mixing patient serum with donor red blood cells 
C)  An immediate spin major crossmatch 
D)  None of the above 
A)  Mixing donor plasma with patient red blood cells 
B)  Mixing patient serum with donor red blood cells 
C)  An immediate spin major crossmatch 
D)  None of the above A

Question 3

All of the following antibodies are clinically significant except:

Accepted Answer

A)  anti-C. 
B)  anti-K. 
C)  anti-Fya. 
D)  anti-Bga. 
A)  anti-C. 
B)  anti-K. 
C)  anti-Fya. 
D)  anti-Bga. D

Question 4

Why is the transfusion product tagged before it is issued and transfused?

Accepted Answer

A)  To identify the patient 
B)  To verify compatibility results 
C)  To verify the donor number 
D)  All of the above 
A)  To identify the patient 
B)  To verify compatibility results 
C)  To verify the donor number 
D)  All of the above

Question 5

Passive acquisition of anti-A, B, AB may occur through:

Accepted Answer

A)  RhIG injection. 
B)  bacterial injection. 
C)  bone marrow transplantation. 
D)  hepatitis vaccination. 
A)  RhIG injection. 
B)  bacterial injection. 
C)  bone marrow transplantation. 
D)  hepatitis vaccination.

Question 6

How long after a transfusion must donor and recipient samples be stored at 1°C to 6°C?

Accepted Answer

A)  7 days 
B)  5 days 
C)  10 days 
D)  14 days 
A)  7 days 
B)  5 days 
C)  10 days 
D)  14 days

Question 7

An immediate spin crossmatch was performed using recipient serum and donor cells from a group AB unit. At immediate spin, the reaction was 4+. What is the reason for this positive reaction?

Accepted Answer

A)  ABO incompatibility 
B)  An alloantibody 
C)  Positive DAT on donor cells 
D)  Positive DAT on recipient cells 
A)  ABO incompatibility 
B)  An alloantibody 
C)  Positive DAT on donor cells 
D)  Positive DAT on recipient cells

Question 8

Which tests must be performed on the donor sample?

Accepted Answer

A)  ABO, Rh, Du, antibody screen 
B)  ABO, Rh, antibody screen 
C)  ABO, Rh, DAT 
D)  All of the above 
A)  ABO, Rh, Du, antibody screen 
B)  ABO, Rh, antibody screen 
C)  ABO, Rh, DAT 
D)  All of the above

Question 9

What does compatibility testing include?

Accepted Answer

A)  ABO, Rh, antibody screen, major crossmatch 
B)  ABO, Rh, DAT, major crossmatch 
C)  ABO, antibody screen, major crossmatch, elution 
D)  ABO, Rh, antibody screen, minor crossmatch 
A)  ABO, Rh, antibody screen, major crossmatch 
B)  ABO, Rh, DAT, major crossmatch 
C)  ABO, antibody screen, major crossmatch, elution 
D)  ABO, Rh, antibody screen, minor crossmatch

Question 10

A 4-unit crossmatch is ordered on a patient for emergency surgery. The patient's blood type is group B-positive. The blood bank inventory only contains two B positive packed cells. What other type is ABO compatible with this patient?

Accepted Answer

A)  A-positive 
B)  A-negative 
C)  AB-positive 
D)  O-negative 
A)  A-positive 
B)  A-negative 
C)  AB-positive 
D)  O-negative

Question 11

During an antiglobulin crossmatch, the cells had a jagged edge appearance after the addition of AHG and centrifugation. This indicates a(n)_____  result.

Accepted Answer

A)  positive 
B)  negative 
C)  inconclusive 
D)  none of the above 
A)  positive 
B)  negative 
C)  inconclusive 
D)  none of the above

Question 12

An ABO antibody will cause a more severe hemolytic transfusion reaction in a patient who has received mismatched blood than an alloantibody will.

Accepted Answer

A) True 
 B)False

Question 13

What tests are not required on autologous units transfused within the collecting facility?

Accepted Answer

A)  ABO 
B)  Rh 
C)  Antibody screen 
D)  None of the above 
A)  ABO 
B)  Rh 
C)  Antibody screen 
D)  None of the above

Question 14

What is an "electronic" crossmatch?

Accepted Answer

A)  A database compiled by the American Red Cross for rare phenotype accessibility 
B)  Comparison of donor and patient ABO groups and serologic data from a computer file 
C)  A crossmatch performed in microtiter plates and read by a spectrophotometer 
D)  All of the above 
A)  A database compiled by the American Red Cross for rare phenotype accessibility 
B)  Comparison of donor and patient ABO groups and serologic data from a computer file 
C)  A crossmatch performed in microtiter plates and read by a spectrophotometer 
D)  All of the above

Question 15

Recipient serum that reacted with one out of five donor units in the AHG phase and where the antibody screen was negative is probably due to:

Accepted Answer

A)  an alloantibody directed against a high-frequency antigen. 
B)  an alloantibody directed against a low-frequency antigen. 
C)  an alloantibody coating the recipient cells. 
D)  an ABO mismatch. 
A)  an alloantibody directed against a high-frequency antigen. 
B)  an alloantibody directed against a low-frequency antigen. 
C)  an alloantibody coating the recipient cells. 
D)  an ABO mismatch.

Question 16

What alternative type can be given to an O-positive person when group O blood is not available?

Accepted Answer

A)  A packed cells 
B)  B packed cells 
C)  AB packed cells 
D)  None of the above 
A)  A packed cells 
B)  B packed cells 
C)  AB packed cells 
D)  None of the above

Question 17

A phlebotomist enters a patient room to draw blood for a 2-unit crossmatch. The patient is not wearing a wristband. How can the patient be identified?

Accepted Answer

A)  Call out the demographic information on the requisition form and ask the patient to verify it. 
B)  Ask patient to state their full name, address, and Social Security number and match responses to information on requisition form. 
C)  Look above the patient's bed for a nameplate. 
D)  Ask his roommate his name. 
A)  Call out the demographic information on the requisition form and ask the patient to verify it. 
B)  Ask patient to state their full name, address, and Social Security number and match responses to information on requisition form. 
C)  Look above the patient's bed for a nameplate. 
D)  Ask his roommate his name.

Question 18

Autoantibodies are generally directed against which antigens?

Accepted Answer

A)  High-frequency 
B)  Low-frequency 
C)  Nonspecific 
D)  ABO 
A)  High-frequency 
B)  Low-frequency 
C)  Nonspecific 
D)  ABO

Question 19

Why is it necessary to use single-donor screening cells instead of pooled screening cells for patient samples?

Accepted Answer

A)  Pooled screening cells are devoid of Duffy antigens 
B)  Single-donor screening cells are free from HIV infection 
C)  Single-donor screening cells are complementary among each other 
D)  None of the above 
A)  Pooled screening cells are devoid of Duffy antigens 
B)  Single-donor screening cells are free from HIV infection 
C)  Single-donor screening cells are complementary among each other 
D)  None of the above

Question 20

In what circumstance would it be feasible to transfuse Rh-positive blood to an Rh-negative individual?

Accepted Answer

A)  In a teenager with anti-D in his serum 
B)  During an emergency cesarean section 
C)  In an elderly woman 
D)  None of the above 
A)  In a teenager with anti-D in his serum 
B)  During an emergency cesarean section 
C)  In an elderly woman 
D)  None of the above

Exam 10: Pre-Transfusion Testing

When would transfusing non-group-specific blood be warranted?

What does the minor crossmatch consist of?

All of the following antibodies are clinically significant except:

Why is the transfusion product tagged before it is issued and transfused?

Passive acquisition of anti-A, B, AB may occur through:

How long after a transfusion must donor and recipient samples be stored at 1°C to 6°C?

An immediate spin crossmatch was performed using recipient serum and donor cells from a group AB unit. At immediate spin, the reaction was 4+. What is the reason for this positive reaction?

Which tests must be performed on the donor sample?

What does compatibility testing include?

A 4-unit crossmatch is ordered on a patient for emergency surgery. The patient's blood type is group B-positive. The blood bank inventory only contains two B positive packed cells. What other type is ABO compatible with this patient?

During an antiglobulin crossmatch, the cells had a jagged edge appearance after the addition of AHG and centrifugation. This indicates a(n)_____ result.

An ABO antibody will cause a more severe hemolytic transfusion reaction in a patient who has received mismatched blood than an alloantibody will.

What tests are not required on autologous units transfused within the collecting facility?

What is an "electronic" crossmatch?

Recipient serum that reacted with one out of five donor units in the AHG phase and where the antibody screen was negative is probably due to:

What alternative type can be given to an O-positive person when group O blood is not available?

A phlebotomist enters a patient room to draw blood for a 2-unit crossmatch. The patient is not wearing a wristband. How can the patient be identified?

Autoantibodies are generally directed against which antigens?

Why is it necessary to use single-donor screening cells instead of pooled screening cells for patient samples?

In what circumstance would it be feasible to transfuse Rh-positive blood to an Rh-negative individual?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters