Question 1

Nucleic acid amplification testing (NAT) is performed for which of the following?

Accepted Answer

A)  HIV, WNV, HCV 
B)  HIV, HCV, HBV 
C)  HIV, HBV, WNV 
D)  HIV, HTLV I,II, HCV 
A)  HIV, WNV, HCV 
B)  HIV, HCV, HBV 
C)  HIV, HBV, WNV 
D)  HIV, HTLV I,II, HCV A

Question 2

A patient who recently stopped taking clopidogrel (Plavix) needs to donate platelets. How long must the patient defer donation after completing the medication?

Accepted Answer

A)  24 hours 
B)  48 hours 
C)  7 days 
D)  14 days 
A)  24 hours 
B)  48 hours 
C)  7 days 
D)  14 days D

Question 3

What is the deferral period for a donor who has received a live attenuated vaccine for rubella?

Accepted Answer

A)  2 weeks 
B)  4 weeks 
C)  no deferral period 
D)  8 weeks 
A)  2 weeks 
B)  4 weeks 
C)  no deferral period 
D)  8 weeks B

Question 4

Which of the following are approved preservative solutions for blood storage at 1°C to 6°C for 21 days?

Accepted Answer

A)  ACD 
B)  CPD 
C)  CP2D 
D)  All of the above 
A)  ACD 
B)  CPD 
C)  CP2D 
D)  All of the above

Question 5

Which of the following statements explains why bacterial contamination of blood is rarely a problem?

Accepted Answer

A)  Regulated procedures for arm preparation prevent most bacteria contamination from occurring during collection. 
B)  Citrate in the anticoagulant is not conducive to bacterial growth. 
C)  The cold storage of blood is not conducive to bacterial growth. 
D)  All of the above 
A)  Regulated procedures for arm preparation prevent most bacteria contamination from occurring during collection. 
B)  Citrate in the anticoagulant is not conducive to bacterial growth. 
C)  The cold storage of blood is not conducive to bacterial growth. 
D)  All of the above

Question 6

In acute normovolemic hemodilution:

Accepted Answer

A)  shed blood is normally reinfused to the patient within 24 hours of collection. 
B)  blood units are reinfused in the reverse order of collection. 
C)  blood units are reinfused in the order of collection. 
D)  the last blood collection should occur no sooner than 72 hours before scheduled surgery. 
A)  shed blood is normally reinfused to the patient within 24 hours of collection. 
B)  blood units are reinfused in the reverse order of collection. 
C)  blood units are reinfused in the order of collection. 
D)  the last blood collection should occur no sooner than 72 hours before scheduled surgery.

Question 7

Methods of preparation of platelet concentrates from single units of whole blood must produce a product that yields a minimum of:

Accepted Answer

A)  5.5 F1F1F1S1F1F1F10 1011 platelets per unit in 50% of units tested. 
B)  5.5 F1F1F1S1F1F1F10 1011 platelets per unit in 75% of units tested. 
C)  5.5 F1F1F1S1F1F1F10 1010 platelets per unit in 75% of units tested. 
D)  none of the above. 
A)  5.5 F1F1F1S1F1F1F10 1011 platelets per unit in 50% of units tested. 
B)  5.5 F1F1F1S1F1F1F10 1011 platelets per unit in 75% of units tested. 
C)  5.5 F1F1F1S1F1F1F10 1010 platelets per unit in 75% of units tested. 
D)  none of the above.

Question 8

Packed RBCs must have a final hematocrit of less than or equal to:

Accepted Answer

A)  85%. 
B)  38%. 
C)  80%. 
D)  70%. 
A)  85%. 
B)  38%. 
C)  80%. 
D)  70%.

Question 9

A patient has a baseline platelet count of 30,000/µL. Upon receiving a platelet pool of 4 random platelets, what would you expect the post-transfusion platelet count to be?

Accepted Answer

A)  35,000/µL 
B)  50,000/µL 
C)  80,000/µL 
D)  100,000/µL 
A)  35,000/µL 
B)  50,000/µL 
C)  80,000/µL 
D)  100,000/µL

Question 10

Which of the following products does not necessarily need to be ABO-compatible in order to be transfused?

Accepted Answer

A)  Cryoprecipitate 
B)  FFP 
C)  Granulocytes 
D)  Deglycerolized RBCs 
A)  Cryoprecipitate 
B)  FFP 
C)  Granulocytes 
D)  Deglycerolized RBCs

Question 11

What is the minimum hemoglobin level for a potential allogeneic donor?

Accepted Answer

A)  11 g/dL 
B)  12 g/dL 
C)  12.5 g/dL 
D)  14 g/dL 
A)  11 g/dL 
B)  12 g/dL 
C)  12.5 g/dL 
D)  14 g/dL

Question 12

The new international bar code system that most blood banks are converting to is:

Accepted Answer

A)  Codabar. 
B)  ISBT. 
C)  Codabar 128. 
D)  Eian 12. 
A)  Codabar. 
B)  ISBT. 
C)  Codabar 128. 
D)  Eian 12.

Question 13

The following blood donors regularly give blood. Which donor may donate on September 11th?

Accepted Answer

A)  A 40-year-old woman who last donated on July 25th 
B)  A 28-year-old man who had plateletpheresis on August 24th 
C)  A 52-year-old man who made an autologous donation on September 9th 
D)  A 23-year-old woman who made a direct donation for her aunt on August 14th 
A)  A 40-year-old woman who last donated on July 25th 
B)  A 28-year-old man who had plateletpheresis on August 24th 
C)  A 52-year-old man who made an autologous donation on September 9th 
D)  A 23-year-old woman who made a direct donation for her aunt on August 14th

Question 14

An autologous unit should be donated what time period prior to the patients surgery/need?

Accepted Answer

A)  72 hours 
B)  48 hours 
C)  1 week 
D)  24 hours 
A)  72 hours 
B)  48 hours 
C)  1 week 
D)  24 hours

Question 15

Cryoprecipitate is indicated for all of the following disorders except:

Accepted Answer

A)  hypofibrinogenemia. 
B)  hemophilia A. 
C)  Von Willebrand's disease. 
D)  hemophilia B. 
A)  hypofibrinogenemia. 
B)  hemophilia A. 
C)  Von Willebrand's disease. 
D)  hemophilia B.

Question 16

A woman received a transfusion of packed RBCs while delivering her baby. Six months later she wanted to donate a unit of blood back to the American Red Cross. If the woman meets all other criteria for donation, is she allowed to donate at this time?

Accepted Answer

A)  Yes, she can donate at this time. 
B)  No, she needs to wait 3 more months. 
C)  No, she needs to wait 6 more months. 
D)  No, she should be on permanent deferral. 
A)  Yes, she can donate at this time. 
B)  No, she needs to wait 3 more months. 
C)  No, she needs to wait 6 more months. 
D)  No, she should be on permanent deferral.

Question 17

A whole blood donor who has taken Tegison should be:

Accepted Answer

A)  accepted. 
B)  deferred for 3 months. 
C)  permanently deferred. 
D)  deferred for 6 months. 
A)  accepted. 
B)  deferred for 3 months. 
C)  permanently deferred. 
D)  deferred for 6 months.

Question 18

All of the following statements are characteristic of a penetrating cryoprotective agent except:

Accepted Answer

A)  it consists of generally small molecules. 
B)  osmotic force prevents migration of water outside of the cell, preventing dehydration. 
C)  large molecules form a shell around the cell, preventing loss of water and dehydration. 
D)  none of the above. 
A)  it consists of generally small molecules. 
B)  osmotic force prevents migration of water outside of the cell, preventing dehydration. 
C)  large molecules form a shell around the cell, preventing loss of water and dehydration. 
D)  none of the above.

Question 19

A unit of red blood cells has an expiration date of 11/15/12. A patient currently on a fludarabine regimen requires irradiated packed red blood cells. The unit is irradiated for this patient on 11/02/12. What is the correct expiration date post-irradiation?

Accepted Answer

A)  11/15/12 
B)  11/30/12 
C)  11/28/12 
D)  11/02/12 
A)  11/15/12 
B)  11/30/12 
C)  11/28/12 
D)  11/02/12

Question 20

What is the minimal pH required for platelets?

Accepted Answer

A)  6.0 
B)  6.2 
C)  7.0 
D)  7.2 
A)  6.0 
B)  6.2 
C)  7.0 
D)  7.2

Exam 13: Donor Screening and Component Preparation

Nucleic acid amplification testing (NAT) is performed for which of the following?

A patient who recently stopped taking clopidogrel (Plavix) needs to donate platelets. How long must the patient defer donation after completing the medication?

What is the deferral period for a donor who has received a live attenuated vaccine for rubella?

Which of the following are approved preservative solutions for blood storage at 1°C to 6°C for 21 days?

Which of the following statements explains why bacterial contamination of blood is rarely a problem?

In acute normovolemic hemodilution:

Methods of preparation of platelet concentrates from single units of whole blood must produce a product that yields a minimum of:

Packed RBCs must have a final hematocrit of less than or equal to:

A patient has a baseline platelet count of 30,000/µL. Upon receiving a platelet pool of 4 random platelets, what would you expect the post-transfusion platelet count to be?

Which of the following products does not necessarily need to be ABO-compatible in order to be transfused?

What is the minimum hemoglobin level for a potential allogeneic donor?

The new international bar code system that most blood banks are converting to is:

The following blood donors regularly give blood. Which donor may donate on September 11th?

An autologous unit should be donated what time period prior to the patients surgery/need?

Cryoprecipitate is indicated for all of the following disorders except:

A woman received a transfusion of packed RBCs while delivering her baby. Six months later she wanted to donate a unit of blood back to the American Red Cross. If the woman meets all other criteria for donation, is she allowed to donate at this time?

A whole blood donor who has taken Tegison should be:

All of the following statements are characteristic of a penetrating cryoprotective agent except:

A unit of red blood cells has an expiration date of 11/15/12. A patient currently on a fludarabine regimen requires irradiated packed red blood cells. The unit is irradiated for this patient on 11/02/12. What is the correct expiration date post-irradiation?

What is the minimal pH required for platelets?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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