Question 1

What is usually required for B cell activation by an antigen?

Accepted Answer

A) other B cells 
B) T cells 
C) platelets 
D) megakaryocytes 
E) erythrocytes 
A) other B cells 
B) T cells 
C) platelets 
D) megakaryocytes 
E) erythrocytes B

Question 2

When an antigen binds to the antibody in the membrane of a B cell,the B cell proliferates and forms a population of B lymphocytes that all make the same antibody.The population of B lymphocytes thus formed is called a(n)_________.

Accepted Answer

A) group 
B) clone 
C) identicon 
D) proliferate 
E) codon 
A) group 
B) clone 
C) identicon 
D) proliferate 
E) codon B

Question 3

How many species of T-cell receptors does each T cell have?

Accepted Answer

A) one 
B) two 
C) up to ten 
D) an infinite number 
E) four 
A) one 
B) two 
C) up to ten 
D) an infinite number 
E) four A

Question 4

What is the primary sorting compartment along the biosynthetic pathway?

Accepted Answer

A) the RER 
B) the trans-Golgi network (TGN) 
C) the cis-Golgi network (CGN) 
D) lysosomes 
E) the plasma membrane 
A) the RER 
B) the trans-Golgi network (TGN) 
C) the cis-Golgi network (CGN) 
D) lysosomes 
E) the plasma membrane

Question 5

You are studying a weasel and find that its genome contains 7 J$\kappa$and 55 V$\kappa$genes.Assuming that any V sequence can join with any J sequence,how many different $\kappa$ chains can this organism make?

Accepted Answer

A) 62 
B) 385 
C) 350 
D) 7 
E) 55 
A) 62 
B) 385 
C) 350 
D) 7 
E) 55

Question 6

What is found on the surface of T cells?

Accepted Answer

A) T cell receptors that allow a specific interaction with a particular antigen 
B) B cells receptors that allow a specific interaction with a particular antigen 
C) T cell antigens that allow a specific interaction with a particular antigen 
D) B cell antigens that allow a specific interaction with a particular antigen 
E) platelet receptors that allow a specific interaction with a particular antigen 
A) T cell receptors that allow a specific interaction with a particular antigen 
B) B cells receptors that allow a specific interaction with a particular antigen 
C) T cell antigens that allow a specific interaction with a particular antigen 
D) B cell antigens that allow a specific interaction with a particular antigen 
E) platelet receptors that allow a specific interaction with a particular antigen

Question 7

The ability of maternal antibodies to get into the fetal circulation can lead to a life-threatening condition in which the fetal red blood cells are killed;this condition is known as ___________.

Accepted Answer

A) lupus erythematosus 
B) erythroblastosis fetalis 
C) aplastic anemia 
D) sickle cell anemia 
E) erythemia 
A) lupus erythematosus 
B) erythroblastosis fetalis 
C) aplastic anemia 
D) sickle cell anemia 
E) erythemia

Question 8

Which class of T cells is composed of primarily inhibitory cells that suppress the proliferation and activities of other types of immune cells that are capable of mounting an autoimmune response?

Accepted Answer

A) helper T lymphocytes 
B) inhibitory T lymphocytes 
C) cytotoxic T lymphocytes 
D) regulatory T lymphocytes 
E) deactivating T lymphocytes 
A) helper T lymphocytes 
B) inhibitory T lymphocytes 
C) cytotoxic T lymphocytes 
D) regulatory T lymphocytes 
E) deactivating T lymphocytes

Question 9

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

Accepted Answer

A) protein rearrangements in the genome 
B) RNA rearrangements in the genome 
C) DNA rearrangements in the genome 
D) DNA rearrangements in the mitochondria 
E) spontaneous production of proteins in the Golgi complex 
A) protein rearrangements in the genome 
B) RNA rearrangements in the genome 
C) DNA rearrangements in the genome 
D) DNA rearrangements in the mitochondria 
E) spontaneous production of proteins in the Golgi complex

Question 10

The heavy chains of which class of antibody bind specifically to macrophage and neutrophil surface receptors,inducing these phagocytes to ingest the particle to which the antibodies are bound?

Accepted Answer

A) IgM 
B) IgG 
C) IgE 
D) IgD 
E) IgA 
A) IgM 
B) IgG 
C) IgE 
D) IgD 
E) IgA

Question 11

Which of the antigens below are typically able to activate B cells without the intercession of T cells?

Accepted Answer

A) very large bacterial lipids 
B) very large viral lipids 
C) bacterial cell wall polysaccharides 
D) bacterial cell wall polypeptides 
E) bacterial DNA 
A) very large bacterial lipids 
B) very large viral lipids 
C) bacterial cell wall polysaccharides 
D) bacterial cell wall polypeptides 
E) bacterial DNA

Question 12

B cells are activated by ________ and T cells are activated by ______.

Accepted Answer

A) soluble,intact antigens;antigen fragments displayed on the surfaces of other cells 
B) soluble,intact antigens;soluble,intact antigens 
C) antigen fragments displayed on the surfaces of other cells;soluble,intact antigens 
D) antigen fragments displayed on the surfaces of other cells;antigen fragments displayed on the surfaces of other cells 
E) insoluble,intact antigens;antigen fragments displayed on the surfaces of other cells 
A) soluble,intact antigens;antigen fragments displayed on the surfaces of other cells 
B) soluble,intact antigens;soluble,intact antigens 
C) antigen fragments displayed on the surfaces of other cells;soluble,intact antigens 
D) antigen fragments displayed on the surfaces of other cells;antigen fragments displayed on the surfaces of other cells 
E) insoluble,intact antigens;antigen fragments displayed on the surfaces of other cells

Question 13

Which cells are responsible for synthesizing and secreting antibodies?

Accepted Answer

A) T cells or lymphocytes 
B) antigen cells 
C) B cells or lymphocytes 
D) platelets 
E) erythrocytes 
A) T cells or lymphocytes 
B) antigen cells 
C) B cells or lymphocytes 
D) platelets 
E) erythrocytes

Question 14

From what do B cells arise?

Accepted Answer

A) T cells 
B) a population of undifferentiated and indistinguishable progenitor cells 
C) a population of differentiated and indistinguishable progenitor cells 
D) a population of undifferentiated and indistinguishable descendent cells 
E) platelets 
A) T cells 
B) a population of undifferentiated and indistinguishable progenitor cells 
C) a population of differentiated and indistinguishable progenitor cells 
D) a population of undifferentiated and indistinguishable descendent cells 
E) platelets

Question 15

How is class switching accomplished?

Accepted Answer

A) by mutation of the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
B) by moving a different CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
C) by inversion of the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
D) by duplicating the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
E) by moving a different CH gene next to the VDJ gene that was formed previously by DNA mutation 
A) by mutation of the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
B) by moving a different CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
C) by inversion of the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
D) by duplicating the CH gene next to the VDJ gene that was formed previously by DNA rearrangement 
E) by moving a different CH gene next to the VDJ gene that was formed previously by DNA mutation

Question 16

_________ immune responses are mounted by the body immediately without requiring previous contact with the microbe;they are the first line of defense and are characterized by a lack of specificity.

Accepted Answer

A) Innate 
B) Acquired 
C) Adaptive 
D) Intuitive 
E) Inductive 
A) Innate 
B) Acquired 
C) Adaptive 
D) Intuitive 
E) Inductive

Question 17

Nucleotide sequence analysis of the V genes indicated that they are ________ than required to encode the V region of the $\kappa$ light chain.

Accepted Answer

A) shorter 
B) longer 
C) the same length as 
D) more coiled 
E) less coiled 
A) shorter 
B) longer 
C) the same length as 
D) more coiled 
E) less coiled

Question 18

The heavy chains of which class of antibody bind and activate one of the complement system proteins,leading to the lysis of the bacterial cell to which the antibody molecules are bound?

Accepted Answer

A) IgM 
B) IgG 
C) IgE 
D) IgD 
E) IgA 
A) IgM 
B) IgG 
C) IgE 
D) IgD 
E) IgA

Question 19

Where do dendritic cells go once they have processed antigens and what do they do when they get there?

Accepted Answer

A) They go to the lymph nodes,where they undergo apoptosis. 
B) They go to the liver,where they undergo apoptosis. 
C) They go to the lymph nodes,where they differentiate into mature antigen-processing cells. 
D) They go to the liver,where they differentiate into mature antigen-processing cells. 
E) They go to the liver,where they proliferate. 
A) They go to the lymph nodes,where they undergo apoptosis. 
B) They go to the liver,where they undergo apoptosis. 
C) They go to the lymph nodes,where they differentiate into mature antigen-processing cells. 
D) They go to the liver,where they differentiate into mature antigen-processing cells. 
E) They go to the liver,where they proliferate.

Question 20

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

Accepted Answer

A) antigens 
B) albumins 
C) heparins 
D) antibodies 
E) thrombospondins 
A) antigens 
B) albumins 
C) heparins 
D) antibodies 
E) thrombospondins

What is usually required for B cell activation by an antigen?

When an antigen binds to the antibody in the membrane of a B cell,the B cell proliferates and forms a population of B lymphocytes that all make the same antibody.The population of B lymphocytes thus formed is called a(n)_________.

How many species of T-cell receptors does each T cell have?

What is the primary sorting compartment along the biosynthetic pathway?

You are studying a weasel and find that its genome contains 7 J $\kappa$ and 55 V $\kappa$ genes.Assuming that any V sequence can join with any J sequence,how many different $\kappa$ chains can this organism make?

What is found on the surface of T cells?

The ability of maternal antibodies to get into the fetal circulation can lead to a life-threatening condition in which the fetal red blood cells are killed;this condition is known as ___________.

Which class of T cells is composed of primarily inhibitory cells that suppress the proliferation and activities of other types of immune cells that are capable of mounting an autoimmune response?

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

The heavy chains of which class of antibody bind specifically to macrophage and neutrophil surface receptors,inducing these phagocytes to ingest the particle to which the antibodies are bound?

Which of the antigens below are typically able to activate B cells without the intercession of T cells?

B cells are activated by __ and T cells are activated by .

Which cells are responsible for synthesizing and secreting antibodies?

From what do B cells arise?

How is class switching accomplished?

_________ immune responses are mounted by the body immediately without requiring previous contact with the microbe;they are the first line of defense and are characterized by a lack of specificity.

Nucleotide sequence analysis of the V genes indicated that they are ________ than required to encode the V region of the $\kappa$ light chain.

The heavy chains of which class of antibody bind and activate one of the complement system proteins,leading to the lysis of the bacterial cell to which the antibody molecules are bound?

Where do dendritic cells go once they have processed antigens and what do they do when they get there?

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes, and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

Techniques in Cell and Molecular Biology

Filters

Exam 17: The Immune Response

What is usually required for B cell activation by an antigen?

When an antigen binds to the antibody in the membrane of a B cell,the B cell proliferates and forms a population of B lymphocytes that all make the same antibody.The population of B lymphocytes thus formed is called a(n)_________.

How many species of T-cell receptors does each T cell have?

What is the primary sorting compartment along the biosynthetic pathway?

You are studying a weasel and find that its genome contains 7 J κ\kappaκ and 55 V κ\kappaκ genes.Assuming that any V sequence can join with any J sequence,how many different κ\kappaκ chains can this organism make?

What is found on the surface of T cells?

The ability of maternal antibodies to get into the fetal circulation can lead to a life-threatening condition in which the fetal red blood cells are killed;this condition is known as ___________.

Which class of T cells is composed of primarily inhibitory cells that suppress the proliferation and activities of other types of immune cells that are capable of mounting an autoimmune response?

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

The heavy chains of which class of antibody bind specifically to macrophage and neutrophil surface receptors,inducing these phagocytes to ingest the particle to which the antibodies are bound?

Which of the antigens below are typically able to activate B cells without the intercession of T cells?

B cells are activated by ________ and T cells are activated by ______.

Which cells are responsible for synthesizing and secreting antibodies?

From what do B cells arise?

How is class switching accomplished?

_________ immune responses are mounted by the body immediately without requiring previous contact with the microbe;they are the first line of defense and are characterized by a lack of specificity.

Nucleotide sequence analysis of the V genes indicated that they are ________ than required to encode the V region of the κ\kappaκ light chain.

The heavy chains of which class of antibody bind and activate one of the complement system proteins,leading to the lysis of the bacterial cell to which the antibody molecules are bound?

Where do dendritic cells go once they have processed antigens and what do they do when they get there?

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes, and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

Techniques in Cell and Molecular Biology

Filters

You are studying a weasel and find that its genome contains 7 J $\kappa$ and 55 V $\kappa$ genes.Assuming that any V sequence can join with any J sequence,how many different $\kappa$ chains can this organism make?

B cells are activated by __ and T cells are activated by .

Nucleotide sequence analysis of the V genes indicated that they are ________ than required to encode the V region of the $\kappa$ light chain.