Exam 9: The Cytoskeleton and Cell Motility

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The point at which the neuron axon terminus and the muscle fiber make contact is called the _________.

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D

An abnormally high level of _______ of the MAP protein tau is implicated in the development of strange,tangled filaments called _________ that have been seen in the brains of patients suffering from several fatal neurodegenerative diseases like Alzheimer's disease.

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A

In cell biology and with respect to microtubules and microfilaments,the word "dynamic" means ________.

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C

Which of the following does not describe the types of microfilament organization normally seen in cells?

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What links actin filament barbed ends to the Z line?

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To which end of microtubules are tubulin subunits primarily added in vitro?

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Which of the following treatments do not disassemble microtubules in living cells?

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What does treatment of a sperm axoneme with 0.6 M NaCl do to its structure?

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From what structure do cilia and flagella emerge?

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Where does the energy to run myosin motors come from?

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_________ proteins are able to alter the three-dimensional organization of an actin filament population.

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Which protein below is often a component of intermediate filaments?

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The myosin filament is characterized as a(n)_________ filament.

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Which region of the sarcomere represents the region of overlap between the two types of filaments in the sarcomere?

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Why does an actin thin filament manage to move continuously during a contraction cycle?

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Which of the following molecular motors is associated with microfilaments?

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Why are taxol,vinblastine and other drugs like them used as chemotherapy agents?

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The central,rod-shaped domain of an intermediate filament is flanked on each side by globular domains of variable size and sequence.What structure forms the core of the central,rod-shaped domain?

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A microscope is equipped with a laser that can be focused on a small region of the cell.The laser beam is used to bleach fluorescent tubulin in a small region of the cell.The specimen is then followed over time and the recovery of the fluorescent signal into the bleached zone is then measured.What is the name of this technique?

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What is the name of the largest protein yet discovered? It extends from the M line in the center of the sarcomere along the myosin filament and past the A band to terminate at the Z line.

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